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Income Taxes (Details) - USD ($)
$ in Millions
3 Months Ended 9 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Sep. 30, 2018
Sep. 30, 2017
Operating Loss Carryforwards [Line Items]        
Effective income tax rate, percentage 18.50% 6.10% 26.20% 24.10%
Acquired in-process research and development $ 30.0 $ 205.0 $ 1,654.5 $ 1,062.6
ARMO and AurKa        
Operating Loss Carryforwards [Line Items]        
Acquired in-process research and development     $ 1,560.0  
Tax Year 2013        
Operating Loss Carryforwards [Line Items]        
Tax year under examination     2013  
Tax Year 2014        
Operating Loss Carryforwards [Line Items]        
Tax year under examination     2014  
Tax Year 2015        
Operating Loss Carryforwards [Line Items]        
Tax year under examination     2015