Consolidated Statements of Operations - USD ($) shares in Thousands, $ in Millions	12 Months Ended
	Dec. 31, 2015	Dec. 31, 2014	Dec. 31, 2013
Revenue	$ 19,958.7	$ 19,615.6	$ 23,113.1
Cost of sales	5,037.2	4,932.5	4,908.1
Research and development	4,796.4	4,733.6	5,531.3
Marketing, selling, and administrative	6,533.0	6,620.8	7,125.6
Acquired in-process research and development	535.0	200.2	57.1
Asset impairment, restructuring, and other special charges	367.7	468.7	120.6
Other-net, (income) expense	(100.6)	(340.5)	(518.9)
Cost of sales, operating expenses, and other-net	17,168.7	16,615.3	17,223.8
Income before income taxes	2,790.0	3,000.3	5,889.3
Income taxes	381.6	609.8	1,204.5
Net income	$ 2,408.4	$ 2,390.5	$ 4,684.8
Earnings Per Share:
Basic	$ 2.27	$ 2.23	$ 4.33
Diluted	$ 2.26	$ 2.23	$ 4.32
Shares used in calculation of earnings per share:
Basic	1,061,913	1,069,932	1,080,874
Diluted	1,065,720	1,074,286	1,084,766