-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
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 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 ND9KAMGFYRdJgrJwLw/DaYAz1zuGwUr+1PkDW3ocnTahDs4dS70QKXmyN9sKPOdc
 mXNn7QxyfqENHEWVjWbzdw==

<SEC-DOCUMENT>0001181431-10-059386.txt : 20101206
<SEC-HEADER>0001181431-10-059386.hdr.sgml : 20101206
<ACCEPTANCE-DATETIME>20101203185246
ACCESSION NUMBER:		0001181431-10-059386
CONFORMED SUBMISSION TYPE:	D
PUBLIC DOCUMENT COUNT:		1
ITEM INFORMATION:		Rule 506
FILED AS OF DATE:		20101206
DATE AS OF CHANGE:		20101203
EFFECTIVENESS DATE:		20101206

FILER:

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			KV PHARMACEUTICAL CO /DE/
		CENTRAL INDEX KEY:			0000057055
		STANDARD INDUSTRIAL CLASSIFICATION:	PHARMACEUTICAL PREPARATIONS [2834]
		IRS NUMBER:				430618919
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			0331

	FILING VALUES:
		FORM TYPE:		D
		SEC ACT:		1933 Act
		SEC FILE NUMBER:	021-151410
		FILM NUMBER:		101232707

	BUSINESS ADDRESS:	
		STREET 1:		ONE CORPORATE WOODS DRIVE
		CITY:			BRIDGETON
		STATE:			MO
		ZIP:			63044
		BUSINESS PHONE:		3146456600

	MAIL ADDRESS:	
		STREET 1:		ONE CORPORATE WOODS DRIVE
		CITY:			BRIDGETON
		STATE:			MO
		ZIP:			63044
</SEC-HEADER>
<DOCUMENT>
<TYPE>D
<SEQUENCE>1
<FILENAME>primary_doc.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<edgarSubmission>

    <schemaVersion>X0704</schemaVersion>

    <submissionType>D</submissionType>

    <testOrLive>LIVE</testOrLive>

    <primaryIssuer>
        <cik>0000057055</cik>
        <entityName>KV PHARMACEUTICAL CO /DE/</entityName>
        <issuerAddress>
            <street1>One Corporate Woods Drive</street1>
            <city>Bridgeton</city>
            <stateOrCountry>MO</stateOrCountry>
            <stateOrCountryDescription>MISSOURI</stateOrCountryDescription>
            <zipCode>63044</zipCode>
        </issuerAddress>
        <issuerPhoneNumber>314-645-6600</issuerPhoneNumber>
        <jurisdictionOfInc>DELAWARE</jurisdictionOfInc>
        <issuerPreviousNameList>
            <value>None</value>
        </issuerPreviousNameList>
        <edgarPreviousNameList>
            <value>None</value>
        </edgarPreviousNameList>
        <entityType>Corporation</entityType>
        <yearOfInc>
            <overFiveYears>true</overFiveYears>
        </yearOfInc>
    </primaryIssuer>

    <relatedPersonsList>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Gregory</firstName>
                <middleName>J.</middleName>
                <lastName>Divis, Jr.</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>One Corporate Woods Drive</street1>
                <city>Bridgeton</city>
                <stateOrCountry>MO</stateOrCountry>
                <stateOrCountryDescription>MISSOURI</stateOrCountryDescription>
                <zipCode>63044</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Gregory</firstName>
                <middleName>S.</middleName>
                <lastName>Bentley</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>One Corporate Woods Drive</street1>
                <city>Bridgeton</city>
                <stateOrCountry>MO</stateOrCountry>
                <stateOrCountryDescription>MISSOURI</stateOrCountryDescription>
                <zipCode>63044</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Thomas</firstName>
                <middleName>S.</middleName>
                <lastName>McHugh</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>One Corporate Woods Drive</street1>
                <city>Bridgeton</city>
                <stateOrCountry>MO</stateOrCountry>
                <stateOrCountryDescription>MISSOURI</stateOrCountryDescription>
                <zipCode>63044</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Executive Officer</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Robert</firstName>
                <middleName>E.</middleName>
                <lastName>Baldini</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>One Corporate Woods Drive</street1>
                <city>Bridgeton</city>
                <stateOrCountry>MO</stateOrCountry>
                <stateOrCountryDescription>MISSOURI</stateOrCountryDescription>
                <zipCode>63044</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Mark</firstName>
                <middleName>A.</middleName>
                <lastName>Dow</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>One Corporate Woods Drive</street1>
                <city>Bridgeton</city>
                <stateOrCountry>MO</stateOrCountry>
                <stateOrCountryDescription>MISSOURI</stateOrCountryDescription>
                <zipCode>63044</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>David</firstName>
                <middleName>S.</middleName>
                <lastName>Hermelin</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>One Corporate Woods Drive</street1>
                <city>Bridgeton</city>
                <stateOrCountry>MO</stateOrCountry>
                <stateOrCountryDescription>MISSOURI</stateOrCountryDescription>
                <zipCode>63044</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Joseph</firstName>
                <middleName>D.</middleName>
                <lastName>Lehrer</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>One Corporate Woods Drive</street1>
                <city>Bridgeton</city>
                <stateOrCountry>MO</stateOrCountry>
                <stateOrCountryDescription>MISSOURI</stateOrCountryDescription>
                <zipCode>63044</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>David</firstName>
                <lastName>Sidransky</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>One Corporate Woods Drive</street1>
                <city>Bridgeton</city>
                <stateOrCountry>MO</stateOrCountry>
                <stateOrCountryDescription>MISSOURI</stateOrCountryDescription>
                <zipCode>63044</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
        <relatedPersonInfo>
            <relatedPersonName>
                <firstName>Ana</firstName>
                <middleName>I.</middleName>
                <lastName>Stancic</lastName>
            </relatedPersonName>
            <relatedPersonAddress>
                <street1>One Corporate Woods Drive</street1>
                <city>Bridgeton</city>
                <stateOrCountry>MO</stateOrCountry>
                <stateOrCountryDescription>MISSOURI</stateOrCountryDescription>
                <zipCode>63044</zipCode>
            </relatedPersonAddress>
            <relatedPersonRelationshipList>
                <relationship>Director</relationship>
            </relatedPersonRelationshipList>
            <relationshipClarification></relationshipClarification>
        </relatedPersonInfo>
    </relatedPersonsList>

    <offeringData>
        <industryGroup>
            <industryGroupType>Pharmaceuticals</industryGroupType>
        </industryGroup>
        <issuerSize>
            <revenueRange>Decline to Disclose</revenueRange>
        </issuerSize>
        <federalExemptionsExclusions>
            <item>06</item>
        </federalExemptionsExclusions>
        <typeOfFiling>
            <newOrAmendment>
                <isAmendment>false</isAmendment>
            </newOrAmendment>
            <dateOfFirstSale>
                <value>2010-11-17</value>
            </dateOfFirstSale>
        </typeOfFiling>
        <durationOfOffering>
            <moreThanOneYear>false</moreThanOneYear>
        </durationOfOffering>
        <typesOfSecuritiesOffered>
            <isOptionToAcquireType>true</isOptionToAcquireType>
        </typesOfSecuritiesOffered>
        <businessCombinationTransaction>
            <isBusinessCombinationTransaction>false</isBusinessCombinationTransaction>
            <clarificationOfResponse></clarificationOfResponse>
        </businessCombinationTransaction>
        <minimumInvestmentAccepted>2492327</minimumInvestmentAccepted>
        <salesCompensationList>
            <recipient>
                <recipientName>Jefferies and Company, Inc.</recipientName>
                <recipientCRDNumber>3247</recipientCRDNumber>
                <associatedBDName>None</associatedBDName>
                <associatedBDCRDNumber>None</associatedBDCRDNumber>
                <recipientAddress>
                    <street1>520 Madison Avenue</street1>
                    <street2>10th Floor</street2>
                    <city>New York</city>
                    <stateOrCountry>NY</stateOrCountry>
                    <stateOrCountryDescription>NEW YORK</stateOrCountryDescription>
                    <zipCode>10022</zipCode>
                </recipientAddress>
                <statesOfSolicitationList>
                    <state>NY</state>
                    <description>NEW YORK</description>
                </statesOfSolicitationList>
                <foreignSolicitation>false</foreignSolicitation>
            </recipient>
        </salesCompensationList>
        <offeringSalesAmounts>
            <totalOfferingAmount>7552506</totalOfferingAmount>
            <totalAmountSold>7552506</totalAmountSold>
            <totalRemaining>0</totalRemaining>
            <clarificationOfResponse></clarificationOfResponse>
        </offeringSalesAmounts>
        <investors>
            <hasNonAccreditedInvestors>false</hasNonAccreditedInvestors>
            <totalNumberAlreadyInvested>2</totalNumberAlreadyInvested>
        </investors>
        <salesCommissionsFindersFees>
            <salesCommissions>
                <dollarAmount>0</dollarAmount>
            </salesCommissions>
            <findersFees>
                <dollarAmount>207694</dollarAmount>
            </findersFees>
            <clarificationOfResponse></clarificationOfResponse>
        </salesCommissionsFindersFees>
        <useOfProceeds>
            <grossProceedsUsed>
                <dollarAmount>0</dollarAmount>
            </grossProceedsUsed>
            <clarificationOfResponse></clarificationOfResponse>
        </useOfProceeds>
        <signatureBlock>
            <authorizedRepresentative>true</authorizedRepresentative>
            <signature>
                <issuerName>KV PHARMACEUTICAL CO /DE/</issuerName>
                <signatureName>/s/ Gregory J. Divis, Jr.</signatureName>
                <nameOfSigner>Gregory J. Divis, Jr.</nameOfSigner>
                <signatureTitle>President and Chief Executive Officer</signatureTitle>
                <signatureDate>2010-12-02</signatureDate>
            </signature>
        </signatureBlock>
    </offeringData>
</edgarSubmission>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----