NPORT-P false 0000052848 XXXXXXXX S000004450 C000012223 C000012222 VANGUARD WORLD FUND 811-01027 0000052848 549300MP6BT0L4Q61L10 100 Vanguard Boulevard Malvern 19355 610-669-1000 VANGUARD HEALTH CARE INDEX FUND S000004450 4G9X037GNB6OUK17TK21 2025-08-31 2025-08-31 N 17571567687.38 1687456.79 17569880230.59 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 0.00000000 2578659.73000000 N Surgery Partners Inc 549300LC82HG33S19I03 86881A100 231634.00000000 NS USD 5255775.46000000 0.029913553143 Long EC CORP US N 1 N N N Varex Imaging Corp 549300CWYWPVCT8E9W67 92214X106 124337.00000000 NS USD 1436092.35000000 0.008173603525 Long EC CORP US N 1 N N N Prevail Therapeutics Inc N/A N/A 78.00000000 NS USD 39.00000000 0.000000221970 Long EC CORP US N 3 N N N Disc Medicine Inc N/A 254604101 68051.00000000 NS USD 4058901.90000000 0.023101477339 Long EC CORP US N 1 N N N N/A N/A N/A 300000.00000000 NC USD 3729000.00000000 0.021223821398 N/A DE N/A N 2 BANK OF AMERICA, N.A. B4TYDEB6GKMZO031MB27 N/A JOHNSON&JOHNSON Y Receive positive return on reference instrument 2025-08-31 0.00000000 USD 0.00000000 USD 49422000.00000000 USD 3729000.00000000 N N N Alumis Inc N/A 022307102 144857.00000000 NS USD 672136.48000000 0.003825504051 Long EC CORP US N 1 N N N Hologic Inc 549300DYP6F5ZJL0LB74 436440101 672709.00000000 NS USD 45152228.08000000 0.256986544514 Long EC CORP US N 1 N N N CG oncology Inc N/A 156944100 127070.00000000 NS USD 3408017.40000000 0.019396930174 Long EC CORP US N 1 N N N Chemed Corp 54930020031IDJT2IM79 16359R103 44265.00000000 NS USD 20271156.75000000 0.115374473154 Long EC CORP US N 1 N N N Embecta Corp 549300RPG8GXVDHNXZ62 29082K105 167314.00000000 NS USD 2422706.72000000 0.013788976863 Long EC CORP US N 1 N N N Terns Pharmaceuticals Inc 254900S1ZDQMF4MYP709 880881107 171768.00000000 NS USD 1195505.28000000 0.006804288158 Long EC CORP US N 1 N N N Thermo Fisher Scientific Inc HCHV7422L5HDJZCRFL38 883556102 1141199.00000000 NS USD 562291571.28000000 3.200315334540 Long EC CORP US N 1 N N N Olema Pharmaceuticals Inc N/A 68062P106 113828.00000000 NS USD 621500.88000000 0.003537308574 Long EC CORP US N 1 N N N Penumbra Inc 549300RGE06P3ECANU72 70975L107 111238.00000000 NS USD 30327928.32000000 0.172613176196 Long EC CORP US N 1 N N N Avantor Inc 5493003VM0XB4U8YD238 05352A100 1900201.00000000 NS USD 25595707.47000000 0.145679464709 Long EC CORP US N 1 N N N Anavex Life Sciences Corp 549300K1I5L8COCQ8W36 032797300 260815.00000000 NS USD 2514256.60000000 0.014310038355 Long EC CORP US N 1 N N Exelixis Inc 254900PJQB59O2O95R37 30161Q104 783494.00000000 NS USD 29318345.48000000 0.166867076469 Long EC CORP US N 1 N N N Mind Medicine MindMed Inc 549300QY8KN1O6RPFJ13 60255C885 182680.00000000 NS USD 1622198.40000000 0.009232836984 Long EC CORP US N 1 N N N Option Care Health Inc 549300DI3Q5ACSYJRI17 68404L201 495756.00000000 NS USD 14218282.08000000 0.080924183280 Long EC CORP US N 1 N N N GE HealthCare Technologies Inc 549300OI9J7XOWZMUN85 36266G107 1384380.00000000 NS USD 102070337.40000000 0.580939289627 Long EC CORP US N 1 N N N Zimmer Biomet Holdings Inc 2P2YLDVPES3BXQ1FRB91 98956P102 598204.00000000 NS USD 63469444.40000000 0.361240051537 Long EC CORP US N 1 N N N Kiniksa Pharmaceuticals International Plc N/A G52694109 102430.00000000 NS USD 3430380.70000000 0.019524212202 Long EC CORP US N 1 N N N Medtronic PLC 549300GX3ZBSQWUXY261 G5960L103 3872998.00000000 NS USD 359452944.38000000 2.045847436991 Long EC CORP US N 1 N N N Prime Medicine Inc N/A 74168J101 286684.00000000 NS USD 928856.16000000 0.005286639110 Long EC CORP US N 1 N N Amicus Therapeutics Inc 549300MRD1SMUTNBPQ53 03152W109 743754.00000000 NS USD 5645092.86000000 0.032129375874 Long EC CORP US N 1 N N N Health Catalyst Inc 549300223PL6GWKVJG92 42225T107 209977.00000000 NS USD 711822.03000000 0.004051376677 Long EC CORP US N 1 N N N Keros Therapeutics Inc N/A 492327101 85888.00000000 NS USD 1306356.48000000 0.007435204240 Long EC CORP US N 1 N N N Align Technology Inc 549300N5YSE0U3LCP840 016255101 207881.00000000 NS USD 29510786.76000000 0.167962367259 Long EC CORP US N 1 N N N Phibro Animal Health Corp 549300U24SP4AF2JUX52 71742Q106 61743.00000000 NS USD 2288813.01000000 0.013026912989 Long EC CORP US N 1 N N N Progyny Inc N/A 74340E103 245917.00000000 NS USD 5820855.39000000 0.033129738584 Long EC CORP US N 1 N N N Simulations Plus Inc N/A 829214105 52160.00000000 NS USD 739107.20000000 0.004206671817 Long EC CORP US N 1 N N N Haemonetics Corp 549300ZEL6TXZS6F5F95 405024100 145019.00000000 NS USD 7909336.26000000 0.045016449493 Long EC CORP US N 1 N N N American Well Corp N/A 03044L204 37869.00000000 NS USD 261296.10000000 0.001487182021 Long EC CORP US N 1 N N N Quest Diagnostics Inc 8MCWUBXQ0WE04KMXBX50 74834L100 337493.00000000 NS USD 61302228.52000000 0.348905215718 Long EC CORP US N 1 N N N Innoviva Inc 549300ACOX4QTBES6535 45781M101 180539.00000000 NS USD 3688411.77000000 0.020992811115 Long EC CORP US N 1 N N N Celldex Therapeutics Inc 529900F018DMYWH38923 15117B202 179555.00000000 NS USD 3964574.40000000 0.022564606861 Long EC CORP US N 1 N N N Pediatrix Medical Group Inc N/A 58502B106 261205.00000000 NS USD 4495338.05000000 0.025585479189 Long EC CORP US N 1 N N N BioCryst Pharmaceuticals Inc 549300Z0INP1Z5NP6J59 09058V103 598787.00000000 NS USD 4975919.97000000 0.028320739269 Long EC CORP US N 1 N N N Envista Holdings Corp 549300BX623VURJZ5269 29415F104 511787.00000000 NS USD 10839648.66000000 0.061694493745 Long EC CORP US N 1 N N N Prothena Corp PLC 5299009ZXQ8NIIJ8OL30 G72800108 130006.00000000 NS USD 1066049.20000000 0.006067481314 Long EC CORP US N 1 N N N United Therapeutics Corp 5299005C4HZL4UWROC14 91307C102 129569.00000000 NS USD 39487448.44000000 0.224745120181 Long EC CORP US N 1 N N N Savara Inc 5493002JO0WM3YMJXG33 805111101 208724.00000000 NS USD 684614.72000000 0.003896524683 Long EC CORP US N 1 N N N Amgen Inc 62QBXGPJ34PQ72Z12S66 031162100 1625374.00000000 NS USD 467636353.54000000 2.661579631748 Long EC CORP US N 1 N N N Halozyme Therapeutics Inc 529900242I3SV9AGM753 40637H109 372700.00000000 NS USD 27263005.00000000 0.155168986027 Long EC CORP US N 1 N N N Perrigo Co PLC 549300IFOQS6R1QLY196 G97822103 415052.00000000 NS USD 9853334.48000000 0.056080828956 Long EC CORP US N 1 N N N Axsome Therapeutics Inc 549300EXGR0XLRJEIB95 05464T104 104032.00000000 NS USD 12617000.96000000 0.071810398217 Long EC CORP US N 1 N N N Immunome Inc N/A 45257U108 210775.00000000 NS USD 2004470.25000000 0.011408559555 Long EC CORP US N 1 N N N AbbVie Inc FR5LCKFTG8054YNNRU85 00287Y109 4489320.00000000 NS USD 944552928.00000000 5.375978183138 Long EC CORP US N 1 N N N Arbutus Biopharma Corp 25490064CESONAUIAS23 03879J100 431454.00000000 NS USD 1600694.34000000 0.009110445370 Long EC CORP US N 1 N N N Pacific Biosciences of California Inc 529900F1BWRE1M0KZN89 69404D108 783564.00000000 NS USD 1026468.84000000 0.005842207382 Long EC CORP US N 1 N N N LENZ Therapeutics Inc N/A 52635N103 34727.00000000 NS USD 1341504.01000000 0.007635248461 Long EC CORP US N 1 N N N ATAI Life Sciences NV 391200Z8UWPJSNBNCA11 N0731H103 448427.00000000 NS USD 2053795.66000000 0.011689298009 Long EC CORP US N 1 N N Doximity Inc N/A 26622P107 372726.00000000 NS USD 25323004.44000000 0.144127359479 Long EC CORP US N 1 N N N BioLife Solutions Inc 549300G2IVCMC2TJDW72 09062W204 122812.00000000 NS USD 3076440.60000000 0.017509741441 Long EC CORP US N 1 N N N Entrada Therapeutics Inc N/A 29384C108 57493.00000000 NS USD 314486.71000000 0.001789919486 Long EC CORP US N 1 N N N Cullinan Therapeutics Inc N/A 230031106 79582.00000000 NS USD 600048.28000000 0.003415209848 Long EC CORP US N 1 N N N Harmony Biosciences Holdings Inc N/A 413197104 130265.00000000 NS USD 4805475.85000000 0.027350646600 Long EC CORP US N 1 N N N KalVista Pharmaceuticals Inc 529900Q7IDA3WUGRZA51 483497103 75377.00000000 NS USD 1014574.42000000 0.005774509596 Long EC CORP US N 1 N N N Stryker Corp 5493002F0SC4JTBU5137 863667101 1039673.00000000 NS USD 406938408.93000000 2.316113733214 Long EC CORP US N 1 N N N Xencor Inc 549300V5IF65437JKG30 98401F105 181259.00000000 NS USD 1473635.67000000 0.008387283525 Long EC CORP US N 1 N N N Soleno Therapeutics Inc 5493003LCY77N7FXK844 834203309 119455.00000000 NS USD 8083519.85000000 0.046007825573 Long EC CORP US N 1 N N N Orthofix Medical Inc N/A 68752M108 94646.00000000 NS USD 1417797.08000000 0.008069474927 Long EC CORP US N 1 N N N Cytek Biosciences Inc 549300K2J28BOC6FBO89 23285D109 329970.00000000 NS USD 1366075.80000000 0.007775100240 Long EC CORP US N 1 N N N MiMedx Group Inc N/A 602496101 356965.00000000 NS USD 2534451.50000000 0.014424978808 Long EC CORP US N 1 N N N ResMed Inc 529900T3QE5253CCXF22 761152107 443248.00000000 NS USD 121676008.48000000 0.692526112205 Long EC CORP US N 1 N N N Kymera Therapeutics Inc N/A 501575104 127145.00000000 NS USD 5238374.00000000 0.029814511716 Long EC CORP US N 1 N N N Premier Inc N/A 74051N102 248705.00000000 NS USD 6441459.50000000 0.036661943140 Long EC CORP US N 1 N N N Sarepta Therapeutics Inc 549300IKDPIED8J8IG21 803607100 267009.00000000 NS USD 4859563.80000000 0.027658491328 Long EC CORP US N 1 N N N Surmodics Inc 549300H76KXCAAGUS878 868873100 43171.00000000 NS USD 1469540.84000000 0.008363977561 Long EC CORP US N 1 N N N Waters Corp 5T547R1474YC9HOD8Q74 941848103 180091.00000000 NS USD 54351463.80000000 0.309344532157 Long EC CORP US N 1 N N N TG Therapeutics Inc 529900X21UKABN9NJ529 88322Q108 455346.00000000 NS USD 13355298.18000000 0.076012459986 Long EC CORP US N 1 N N N Tango Therapeutics Inc N/A 87583X109 130886.00000000 NS USD 878245.06000000 0.004998583077 Long EC CORP US N 1 N N N Ligand Pharmaceuticals Inc 5493008K7TB0IKP37H79 53220K504 58244.00000000 NS USD 9418637.24000000 0.053606724214 Long EC CORP US N 1 N N N Apogee Therapeutics Inc N/A 03770N101 67302.00000000 NS USD 2447773.74000000 0.013931647272 Long EC CORP US N 1 N N N Coherus Oncology Inc 5493007IL8W5MV932D26 19249H103 336090.00000000 NS USD 389864.40000000 0.002218936013 Long EC CORP US N 1 N N N Applied Therapeutics Inc 549300KL3IJPHZM2GR04 03828A101 323786.00000000 NS USD 159529.36000000 0.000907970674 Long EC CORP US N 1 N N N Twist Bioscience Corp 549300T23BL59LCOH584 90184D100 180370.00000000 NS USD 4864578.90000000 0.027687035063 Long EC CORP US N 1 N N N DaVita Inc M2XHYMU3TZNEZURC6H66 23918K108 125403.00000000 NS USD 17275517.28000000 0.098324616066 Long EC CORP US N 1 N N N Solventum Corp 254900I70403OSGY4M28 83444M101 471041.00000000 NS USD 34428386.69000000 0.195951174613 Long EC CORP US N 1 N N N GeneDx Holdings Corp N/A 81663L200 55997.00000000 NS USD 7251051.53000000 0.041269783486 Long EC CORP US N 1 N N N Alignment Healthcare Inc N/A 01625V104 418211.00000000 NS USD 6841931.96000000 0.038941255547 Long EC CORP US N 1 N N N AdaptHealth Corp N/A 00653Q102 285368.00000000 NS USD 2708142.32000000 0.015413550260 Long EC CORP US N 1 N N N Dyne Therapeutics Inc N/A 26818M108 277720.00000000 NS USD 3746442.80000000 0.021323098113 Long EC CORP US N 1 N N N Medpace Holdings Inc 549300H8TYEUVTW14A54 58506Q109 73887.00000000 NS USD 35134007.37000000 0.199967255945 Long EC CORP US N 1 N N N Avidity Biosciences Inc N/A 05370A108 273506.00000000 NS USD 12739909.48000000 0.072509939241 Long EC CORP US N 1 N N N Certara Inc N/A 15687V109 367363.00000000 NS USD 3982214.92000000 0.022665008911 Long EC CORP US N 1 N N N OPKO Health Inc 529900A4S2D4OGOJLL02 68375N103 1317750.00000000 NS USD 1818495.00000000 0.010350070553 Long EC CORP US N 1 N N N Phreesia Inc 5493000HHF8NU4QOCG53 71944F106 179648.00000000 NS USD 5687655.68000000 0.032371624651 Long EC CORP US N 1 N N N Korro Bio Inc N/A 500946108 13773.00000000 NS USD 317880.84000000 0.001809237375 Long EC CORP US N 1 N N N Hims & Hers Health Inc 549300ZQ4ZUYSAAX6P59 433000106 586567.00000000 NS USD 24841112.45000000 0.141384643059 Long EC CORP US N 1 N N N Bristol-Myers Squibb Co HLYYNH7UQUORYSJQCN42 110122108 6151869.00000000 NS USD 290245179.42000000 1.651947398677 Long EC CORP US N 1 N N N Cigna Group/The 549300VIWYMSIGT1U456 125523100 807553.00000000 NS USD 242968471.11000000 1.382869250793 Long EC CORP US N 1 N N N Nuvalent Inc N/A 670703107 120362.00000000 NS USD 9217321.96000000 0.052460926534 Long EC CORP US N 1 N N N IQVIA Holdings Inc 549300W3R20NM4KQPH86 46266C105 522258.00000000 NS USD 99652048.98000000 0.567175459776 Long EC CORP US N 1 N N N 89bio Inc N/A 282559103 330601.00000000 NS USD 2985327.03000000 0.016991163234 Long EC CORP US N 1 N N N WaVe Life Sciences Ltd 54930070006GPKFYZ813 Y95308105 330469.00000000 NS USD 3172502.40000000 0.018056482789 Long EC CORP US N 1 N N N Roivant Sciences Ltd 549300DL466NY5J6U724 G76279101 922784.00000000 NS USD 11008813.12000000 0.062657303154 Long EC CORP US N 1 N N N Rocket Pharmaceuticals Inc 549300R7VV82YUIN4Y93 77313F106 243880.00000000 NS USD 799926.40000000 0.004552827848 Long EC CORP US N 1 N N N Mural Oncology PLC N/A G63365103 45854.00000000 NS USD 94459.24000000 0.000537620284 Long EC CORP US N 1 N N N Arrowhead Pharmaceuticals Inc 549300O3CSB8T7OZ3D66 04280A100 334716.00000000 NS USD 7373793.48000000 0.041968376467 Long EC CORP US N 1 N N N Dianthus Therapeutics Inc 549300Z3N6ODPCOFC890 252828108 24614.00000000 NS USD 580151.98000000 0.003301968894 Long EC CORP US N 1 N N N Adaptive Biotechnologies Corp 549300ZTF7OT1FW66Q96 00650F109 321180.00000000 NS USD 4233152.40000000 0.024093234242 Long EC CORP US N 1 N N N Regeneron Pharmaceuticals Inc 549300RCBFWIRX3HYQ56 75886F107 320898.00000000 NS USD 186345468.60000000 1.060596123333 Long EC CORP US N 1 N N N Bioventus Inc N/A 09075A108 120295.00000000 NS USD 890183.00000000 0.005066528560 Long EC CORP US N 1 N N N Sana Biotechnology Inc N/A 799566104 409183.00000000 NS USD 1252099.98000000 0.007126400200 Long EC CORP US N 1 N N Arvinas Inc N/A 04335A105 176229.00000000 NS USD 1362250.17000000 0.007753326443 Long EC CORP US N 1 N N N STAAR Surgical Co 5299006LRHI7OJ8BY308 852312305 104389.00000000 NS USD 2856083.04000000 0.016255563512 Long EC CORP US N 1 N N N Recursion Pharmaceuticals Inc N/A 75629V104 966375.00000000 NS USD 4541962.50000000 0.025850844970 Long EC CORP US N 1 N N agilon health Inc N/A 00857U107 936003.00000000 NS USD 1198083.84000000 0.006818964183 Long EC CORP US N 1 N N N DENTSPLY SIRONA Inc 9NHEHR1SOZCYXDO8HO28 24906P109 604666.00000000 NS USD 8646723.80000000 0.049213333765 Long EC CORP US N 1 N N N Bridgebio Pharma Inc 54930028YG89VTY2J114 10806X102 430967.00000000 NS USD 22306851.92000000 0.126960751167 Long EC CORP US N 1 N N N Enovis Corp 635400OP2DYYYMOIYL17 194014502 172943.00000000 NS USD 5343938.70000000 0.030415339375 Long EC CORP US N 1 N N N Ocugen Inc 549300JVNUI9CXWJLR09 67577C105 876450.00000000 NS USD 893979.00000000 0.005088133716 Long EC CORP US N 1 N N Nurix Therapeutics Inc N/A 67080M103 207885.00000000 NS USD 1941645.90000000 0.011050991096 Long EC CORP US N 1 N N N HCA Healthcare Inc 529900PH4ZGUH2MNEU89 40412C101 545420.00000000 NS USD 220327863.20000000 1.254008907905 Long EC CORP US N 1 N N N Bruker Corp LEBZ6VLQ6I8XB1NHVY15 116794108 320575.00000000 NS USD 10893138.50000000 0.061998934295 Long EC CORP US N 1 N N N AngioDynamics Inc 549300W3VKC5ZKMO8C28 03475V101 122759.00000000 NS USD 1259507.34000000 0.007168559622 Long EC CORP US N 1 N N N PROCEPT BioRobotics Corp N/A 74276L105 167019.00000000 NS USD 6709153.23000000 0.038185537647 Long EC CORP US N 1 N N N BioMarin Pharmaceutical Inc NSLL8ITTRR0J5HEMR848 09061G101 580044.00000000 NS USD 33799163.88000000 0.192369916222 Long EC CORP US N 1 N N N Amylyx Pharmaceuticals Inc N/A 03237H101 175019.00000000 NS USD 1641678.22000000 0.009343707517 Long EC CORP US N 1 N N N Edgewise Therapeutics Inc N/A 28036F105 158820.00000000 NS USD 2279067.00000000 0.012971443004 Long EC CORP US N 1 N N N Vanguard Cmt Funds-Vanguard Market Liquidity Fund 1I6HV0TLSTR3A4XQ6L78 N/A 597727.93500000 NS USD 59766816.22000000 0.340166326893 Long STIV CORP US N 1 N N Illumina Inc SQ95QG8SR5Q56LSNF682 452327109 478827.00000000 NS USD 47863546.92000000 0.272418174124 Long EC CORP US N 1 N N N Aldeyra Therapeutics Inc 529900HGKY864E4Y9014 01438T106 145122.00000000 NS USD 847512.48000000 0.004823666802 Long EC CORP US N 1 N N N Xeris Biopharma Holdings Inc N/A 98422E103 483673.00000000 NS USD 3787159.59000000 0.021554840103 Long EC CORP US N 1 N N N Biogen Inc W8J5WZB5IY3K0NDQT671 09062X103 443174.00000000 NS USD 58596466.28000000 0.333505211822 Long EC CORP US N 1 N N N Merck & Co Inc 4YV9Y5M8S0BRK1RP0397 58933Y105 7590407.00000000 NS USD 638505036.84000000 3.634088727186 Long EC CORP US N 1 N N N Ventyx Biosciences Inc N/A 92332V107 162995.00000000 NS USD 391188.00000000 0.002226469360 Long EC CORP US N 1 N N N Ardelyx Inc 549300F542QR4SXHCY32 039697107 725403.00000000 NS USD 4613563.08000000 0.026258363855 Long EC CORP US N 1 N N N Organon & Co 549300AMCKY57OK2CO56 68622V106 785035.00000000 NS USD 7395029.70000000 0.042089243654 Long EC CORP US N 1 N N N National HealthCare Corp N/A 635906100 39992.00000000 NS USD 4538292.16000000 0.025829955016 Long EC CORP US N 1 N N N HealthEquity Inc 529900LRJU1RAFQHM467 42226A107 261642.00000000 NS USD 23372479.86000000 0.133025834856 Long EC CORP US N 1 N N N Azenta Inc 35ZN6X1ANPH25YN32Y17 114340102 125438.00000000 NS USD 3830876.52000000 0.021803657564 Long EC CORP US N 1 N N N Theravance Biopharma Inc 5493007VTSXP4Z6MIW52 G8807B106 114032.00000000 NS USD 1582764.16000000 0.009008394702 Long EC CORP US N 1 N N N Praxis Precision Medicines Inc N/A 74006W207 55341.00000000 NS USD 2520229.14000000 0.014344031415 Long EC CORP US N 1 N N N Aura Biosciences Inc N/A 05153U107 149870.00000000 NS USD 938186.20000000 0.005339741578 Long EC CORP US N 1 N N N Newamsterdam Pharma Co NV 984500B6549TF6E14D36 N/A 135616.00000000 NS USD 3261564.80000000 0.018563386643 Long EC CORP US N 1 N N N Harrow Inc N/A 415858109 93991.00000000 NS USD 3665649.00000000 0.020863255479 Long EC CORP US N 1 N N N Akero Therapeutics Inc 549300SI3KG74LBE2955 00973Y108 169067.00000000 NS USD 7900500.91000000 0.044966162582 Long EC CORP US N 1 N N N Emergent BioSolutions Inc 549300YW6TUOX8BE5103 29089Q105 164754.00000000 NS USD 1367458.20000000 0.007782968250 Long EC CORP US N 1 N N N Standard BioTools Inc 549300GX8Y96GSB6YP89 34385P108 745964.00000000 NS USD 939914.64000000 0.005349579095 Long EC CORP US N 1 N N N Baxter International Inc J5OIVXX3P24RJRW5CK77 071813109 1552329.00000000 NS USD 38327003.01000000 0.218140377207 Long EC CORP US N 1 N N N Summit Therapeutics Inc N/A 86627T108 448436.00000000 NS USD 10627933.20000000 0.060489502833 Long EC CORP US N 1 N N RadNet Inc 529900RECG94V2IZJ970 750491102 197564.00000000 NS USD 14177192.64000000 0.080690320331 Long EC CORP US N 1 N N N GoodRx Holdings Inc N/A 38246G108 259334.00000000 NS USD 1128102.90000000 0.006420663574 Long EC CORP US N 1 N N N Sotera Health Co N/A 83601L102 473701.00000000 NS USD 7754485.37000000 0.044135106604 Long EC CORP US N 1 N N N Agenus Inc 529900NDQQGU5H4UJK81 00847G804 87945.00000000 NS USD 367610.10000000 0.002092274364 Long EC CORP US N 1 N N N US Physical Therapy Inc 529900KL1UXQYFIOMY96 90337L108 45894.00000000 NS USD 3804153.66000000 0.021651562845 Long EC CORP US N 1 N N N MeiraGTx Holdings plc 54930007YV6NYIOGFZ57 G59665102 131251.00000000 NS USD 958132.30000000 0.005453265972 Long EC CORP US N 1 N N N SIGA Technologies Inc N/A 826917106 130094.00000000 NS USD 1091488.66000000 0.006212271487 Long EC CORP US N 1 N N N Encompass Health Corp 549300FVRPM9DRQZRG64 29261A100 304781.00000000 NS USD 37110134.56000000 0.211214499319 Long EC CORP US N 1 N N N OraSure Technologies Inc 529900GNNJPNM4XHXQ77 68554V108 208929.00000000 NS USD 691554.99000000 0.003936025635 Long EC CORP US N 1 N N N Protagonist Therapeutics Inc N/A 74366E102 149728.00000000 NS USD 8841438.40000000 0.050321563288 Long EC CORP US N 1 N N N N/A N/A N/A 162000.00000000 NC USD 4860.00000000 0.000027660973 N/A DE N/A N 2 BANK OF AMERICA, N.A. B4TYDEB6GKMZO031MB27 N/A AVANTOR INC Y Receive positive return on reference instrument 2025-08-31 0.00000000 USD 0.00000000 USD 2177280.00000000 USD 4860.00000000 N N N Astria Therapeutics Inc N/A 04635X102 85649.00000000 NS USD 529310.82000000 0.003012603461 Long EC CORP US N 1 N N N Charles River Laboratories International Inc 549300BSQ0R4UZ5KX287 159864107 148625.00000000 NS USD 24271948.75000000 0.138145214602 Long EC CORP US N 1 N N N Zimvie Inc 549300GFKURT1J6XR665 98888T107 84686.00000000 NS USD 1598871.68000000 0.009100071594 Long EC CORP US N 1 N N N NeoGenomics Inc N/A 64049M209 388961.00000000 NS USD 3415077.58000000 0.019437113601 Long EC CORP US N 1 N N N Inspire Medical Systems Inc 549300XQQCQ7HCJKTW25 457730109 84577.00000000 NS USD 7924019.13000000 0.045100017905 Long EC CORP US N 1 N N N Butterfly Network Inc N/A 124155102 567100.00000000 NS USD 913031.00000000 0.005196569287 Long EC CORP US N 1 N N N Zentalis Pharmaceuticals Inc N/A 98943L107 135940.00000000 NS USD 229738.60000000 0.001307570666 Long EC CORP US N 1 N N N Perspective Therapeutics Inc 5493005LRKM6BCABC605 46489V302 168245.00000000 NS USD 565303.20000000 0.003217456195 Long EC CORP US N 1 N N N Mirum Pharmaceuticals Inc 254900YZKR40F7F27K81 604749101 112178.00000000 NS USD 8286588.86000000 0.047163604710 Long EC CORP US N 1 N N N Teleflex Inc UUL85LWXB4NGSWWXIQ25 879369106 133402.00000000 NS USD 16863346.82000000 0.095978723808 Long EC CORP US N 1 N N N Immunovant Inc N/A 45258J102 205829.00000000 NS USD 3023628.01000000 0.017209155499 Long EC CORP US N 1 N N N Ultragenyx Pharmaceutical Inc 529900EV44GVDN1DCX77 90400D108 256821.00000000 NS USD 7694357.16000000 0.043792883383 Long EC CORP US N 1 N N N Day One Biopharmaceuticals Inc N/A 23954D109 199593.00000000 NS USD 1498943.43000000 0.008531324120 Long EC CORP US N 1 N N N Relay Therapeutics Inc N/A 75943R102 358361.00000000 NS USD 1286515.99000000 0.007322280932 Long EC CORP US N 1 N N N Maravai LifeSciences Holdings Inc N/A 56600D107 325718.00000000 NS USD 788237.56000000 0.004486300132 Long EC CORP US N 1 N N N Community Health Systems Inc N/A 203668108 382179.00000000 NS USD 1054814.04000000 0.006003535745 Long EC CORP US N 1 N N N Allogene Therapeutics Inc N/A 019770106 446815.00000000 NS USD 504900.95000000 0.002873673259 Long EC CORP US N 1 N N N 10X Genomics Inc 5493003Z6741WNLG7H43 88025U109 301916.00000000 NS USD 4229843.16000000 0.024074399509 Long EC CORP US N 1 N N N Erasca Inc N/A 29479A108 517730.00000000 NS USD 812836.10000000 0.004626304159 Long EC CORP US N 1 N N N Arcutis Biotherapeutics Inc N/A 03969K108 322884.00000000 NS USD 5011159.68000000 0.028521308137 Long EC CORP US N 1 N N N Pfizer Inc 765LHXWGK1KXCLTFYQ30 717081103 17186528.00000000 NS USD 425538433.28000000 2.421976858664 Long EC CORP US N 1 N N N Akebia Therapeutics Inc 549300CBQEHMKEEGNX42 00972D105 793549.00000000 NS USD 2491743.86000000 0.014181905780 Long EC CORP US N 1 N N N Enhabit Inc 549300RFQ78SLDFSHF49 29332G102 130463.00000000 NS USD 1028048.44000000 0.005851197768 Long EC CORP US N 1 N N N LivaNova PLC 2138001K2FX6SHK2B339 G5509L101 165208.00000000 NS USD 9312774.96000000 0.053004202861 Long EC CORP US N 1 N N N Artivion Inc 549300YTKV8DMSMG6K81 228903100 109834.00000000 NS USD 4825007.62000000 0.027461812810 Long EC CORP US N 1 N N N ACADIA Pharmaceuticals Inc 529900O3044NO0PEA039 004225108 353807.00000000 NS USD 9195443.93000000 0.052336406448 Long EC CORP US N 1 N N N ANI Pharmaceuticals Inc 5493000T6CXTND40YH31 00182C103 52202.00000000 NS USD 4880887.00000000 0.027779853567 Long EC CORP US N 1 N N N Ensign Group Inc/The 5493003K4HEEA8Q0BC72 29358P101 173866.00000000 NS USD 29866701.48000000 0.169988076685 Long EC CORP US N 1 N N N Mesa Laboratories Inc 549300ZCG738WLX8ZW79 59064R109 16542.00000000 NS USD 1120720.50000000 0.006378646213 Long EC CORP US N 1 N N N Editas Medicine Inc 5299000AON4Q9NT2JE42 28106W103 260607.00000000 NS USD 669759.99000000 0.003811978119 Long EC CORP US N 1 N N N Elevance Health Inc 8MYN82XMYQH89CTMTH67 036752103 683003.00000000 NS USD 217638905.95000000 1.238704550592 Long EC CORP US N 1 N N N Revvity Inc 549300IKL1SDPFI7N655 714046109 355868.00000000 NS USD 32067265.48000000 0.182512715278 Long EC CORP US N 1 N N N Vanda Pharmaceuticals Inc 529900AY8VOOQBKJ0O70 921659108 168222.00000000 NS USD 795690.06000000 0.004528716471 Long EC CORP US N 1 N N N 4D Molecular Therapeutics Inc N/A 35104E100 98988.00000000 NS USD 609766.08000000 0.003470519275 Long EC CORP US N 1 N N N LifeStance Health Group Inc N/A 53228F101 408753.00000000 NS USD 2239966.44000000 0.012748899882 Long EC CORP US N 1 N N N OmniAb Inc N/A 68218J202 22076.00000000 NS USD 0.22000000 0.000000001252 Long EC CORP US N 3 N N N AnaptysBio Inc 529900HH4WQT03IG1A12 032724106 44331.00000000 NS USD 901249.23000000 0.005129512655 Long EC CORP US N 1 N N N N/A N/A N/A 850000.00000000 NC USD 10565500.00000000 0.060134160627 N/A DE N/A N 2 BANK OF AMERICA, N.A. B4TYDEB6GKMZO031MB27 N/A JOHNSON&JOHNSON Y Receive positive return on reference instrument 2025-08-31 0.00000000 USD 0.00000000 USD 140029000.00000000 USD 10565500.00000000 N N N Scholar Rock Holding Corp 549300Z1FLPGL4OWJ459 80706P103 186355.00000000 NS USD 6084490.75000000 0.034630234641 Long EC CORP US N 1 N N N Tarsus Pharmaceuticals Inc N/A 87650L103 95118.00000000 NS USD 5572012.44000000 0.031713434393 Long EC CORP US N 1 N N N Evolent Health Inc 549300CZOCFHQ2BBTR11 30050B101 299826.00000000 NS USD 2893320.90000000 0.016467504968 Long EC CORP US N 1 N N N N/A N/A N/A 550000.00000000 NC USD 11758994.50000000 0.066927004314 N/A DE N/A N 2 BANK OF AMERICA, N.A. B4TYDEB6GKMZO031MB27 N/A ABBVIE INC Y Receive positive return on reference instrument 2025-08-31 0.00000000 USD 0.00000000 USD 103961000.00000000 USD 11758994.50000000 N N N Lantheus Holdings Inc 5299005HUB5IOJGO7S39 516544103 208858.00000000 NS USD 11466304.20000000 0.065261140369 Long EC CORP US N 1 N N N Amphastar Pharmaceuticals Inc 54930055TH0ZLSAQMJ38 03209R103 113456.00000000 NS USD 3474022.72000000 0.019772603309 Long EC CORP US N 1 N N N Catalyst Pharmaceuticals Inc 5299004O0R5XXLA5H544 14888U101 350459.00000000 NS USD 7215950.81000000 0.041070005687 Long EC CORP US N 1 N N N Globus Medical Inc 5299003M2P4CIK0RF205 379577208 240980.00000000 NS USD 14764844.60000000 0.084034975800 Long EC CORP US N 1 N N N Fate Therapeutics Inc 549300L14Q4UHOODLA90 31189P102 294485.00000000 NS USD 306264.40000000 0.001743121728 Long EC CORP US N 1 N N N Teladoc Health Inc 549300I2PVFBC9MFAC61 87918A105 530279.00000000 NS USD 4099056.67000000 0.023330020559 Long EC CORP US N 1 N N N Replimune Group Inc 549300AY704NEIRC4K64 76029N106 116626.00000000 NS USD 629780.40000000 0.003584431946 Long EC CORP US N 1 N N N Veracyte Inc 529900ESWZRHXOW27Z37 92337F107 237435.00000000 NS USD 7203777.90000000 0.041000722858 Long EC CORP US N 1 N N N Stoke Therapeutics Inc 549300RD25SS2DIJHJ67 86150R107 115442.00000000 NS USD 2281133.92000000 0.012983207000 Long EC CORP US N 1 N N N Henry Schein Inc VGO3WGL8H45T73F4RR92 806407102 340395.00000000 NS USD 23684684.10000000 0.134802763531 Long EC CORP US N 1 N N N Avanos Medical Inc 549300YCXWOM7NEWMQ58 05350V106 140647.00000000 NS USD 1679325.18000000 0.009557977390 Long EC CORP US N 1 N N N Taysha Gene Therapies Inc N/A 877619106 513393.00000000 NS USD 1499107.56000000 0.008532258275 Long EC CORP US N 1 N N N Crinetics Pharmaceuticals Inc 549300Q1CNFXK5P31D28 22663K107 268581.00000000 NS USD 8323325.19000000 0.047372691678 Long EC CORP US N 1 N N N Pliant Therapeutics Inc 5493002Q5LITR7VHZH02 729139105 146506.00000000 NS USD 240269.84000000 0.001367509834 Long EC CORP US N 1 N N N Incyte Corp 549300Z4WN6JVZ3T4680 45337C102 497430.00000000 NS USD 42087552.30000000 0.239543763233 Long EC CORP US N 1 N N N CryoPort Inc 9845004D8538BT8JF626 229050307 150821.00000000 NS USD 1336274.06000000 0.007605481895 Long EC CORP US N 1 N N N Ionis Pharmaceuticals Inc 549300SI4ZGLG0BLUZ92 462222100 456495.00000000 NS USD 19462664.33000000 0.110772891303 Long EC CORP US N 1 N N N Biohaven Ltd N/A G1110E107 262505.00000000 NS USD 4039951.95000000 0.022993622591 Long EC CORP US N 1 N N N Krystal Biotech Inc 549300YONUY68210OE41 501147102 65673.00000000 NS USD 9699902.10000000 0.055207559600 Long EC CORP US N 1 N N N Organogenesis Holdings Inc 549300RLC2O821TU6941 68621F102 177845.00000000 NS USD 915901.75000000 0.005212908329 Long EC CORP US N 1 N N N Ceribell Inc N/A 15678C102 49042.00000000 NS USD 580166.86000000 0.003302053584 Long EC CORP US N 1 N N N Nuvation Bio Inc N/A 67080N101 563062.00000000 NS USD 1672294.14000000 0.009517959815 Long EC CORP US N 1 N N Neurocrine Biosciences Inc 549300FECER0XBN49756 64125C109 299228.00000000 NS USD 41772228.80000000 0.237749081107 Long EC CORP US N 1 N N N Jazz Pharmaceuticals PLC 635400GAUMJCLEZRRV50 G50871105 173546.00000000 NS USD 22170501.50000000 0.126184704784 Long EC CORP US N 1 N N N ARS Pharmaceuticals Inc N/A 82835W108 133602.00000000 NS USD 1552455.24000000 0.008835889713 Long EC CORP US N 1 N N N Vanguard Cmt Funds-Vanguard Market Liquidity Fund 1I6HV0TLSTR3A4XQ6L78 N/A 562644023.60000000 NS USD 562587759.20000000 3.202001105394 Long STIV CORP US N 1 N N N Boston Scientific Corp Y6ZDD9FP4P8JSSJMW954 101137107 4471840.00000000 NS USD 471779120.00000000 2.685158429131 Long EC CORP US N 1 N N N Eli Lilly & Co FRDRIPF3EKNDJ2CQJL29 532457108 2435020.00000000 NS USD 1783846951.60000000 10.15286916124 Long EC CORP US N 1 N N N Elanco Animal Health Inc 549300SHPNDCE059M934 28414H103 1500154.00000000 NS USD 27527825.90000000 0.156676229653 Long EC CORP US N 1 N N N CRISPR Therapeutics AG 506700O6IRRIQLT3W370 H17182108 248419.00000000 NS USD 12875556.77000000 0.073281983718 Long EC CORP US N 1 N N Avadel Pharmaceuticals PLC 549300E27PTSG2RHC762 G29687103 263046.00000000 NS USD 3882558.96000000 0.022097811191 Long EC CORP US N 1 N N N MaxCyte Inc 54930053YHXULRFCU991 57777K106 303889.00000000 NS USD 422405.71000000 0.002404146781 Long EC CORP US N 1 N N N Tempus AI Inc N/A 88023B103 279792.00000000 NS USD 21225021.12000000 0.120803447954 Long EC CORP US N 1 N N Heron Therapeutics Inc 549300DR2I1DOPD2IX53 427746102 371134.00000000 NS USD 501030.90000000 0.002851646644 Long EC CORP US N 1 N N N Enliven Therapeutics Inc N/A 29337E102 98312.00000000 NS USD 1992784.24000000 0.011342047947 Long EC CORP US N 1 N N N Abbott Laboratories HQD377W2YR662HK5JX27 002824100 5258961.00000000 NS USD 697653766.26000000 3.970737176940 Long EC CORP US N 1 N N N Owens & Minor Inc 549300LMT5KQQXCEZ733 690732102 232342.00000000 NS USD 1138475.80000000 0.006479701540 Long EC CORP US N 1 N N N QuidelOrtho Corp 549300YU8CMO9HF53113 219798105 204952.00000000 NS USD 5880072.88000000 0.033466778389 Long EC CORP US N 1 N N N Myriad Genetics Inc 52990044IHUOUMETT163 62855J104 276692.00000000 NS USD 1762528.04000000 0.010031531330 Long EC CORP US N 1 N N N Addus HomeCare Corp 52990090ZT33AKPDBX62 006739106 55566.00000000 NS USD 6399536.22000000 0.036423334342 Long EC CORP US N 1 N N N ChromaDex Corp 529900OPI7B8JPXCVS70 171077407 169637.00000000 NS USD 1679406.30000000 0.009558439089 Long EC CORP US N 1 N N N HilleVax Inc N/A 43157M102 59032.00000000 NS USD 123376.88000000 0.000702206721 Long EC CORP US N 1 N N N Spyre Therapeutics Inc 52990017AIJPRH3HQH40 00773J202 109766.00000000 NS USD 1810041.34000000 0.010301956053 Long EC CORP US N 1 N N N CareDx Inc 549300NQOFKL9NON0U06 14167L103 159584.00000000 NS USD 2179917.44000000 0.012407127489 Long EC CORP US N 1 N N N Rhythm Pharmaceuticals Inc 529900JPNWXQ8DPLA551 76243J105 159395.00000000 NS USD 16441594.25000000 0.093578294411 Long EC CORP US N 1 N N N Arcus Biosciences Inc N/A 03969F109 207812.00000000 NS USD 2200729.08000000 0.012525578154 Long EC CORP US N 1 N N N Evolus Inc 549300VYQRYBQOT8V419 30052C107 144248.00000000 NS USD 1100612.24000000 0.006264198876 Long EC CORP US N 1 N N N Madrigal Pharmaceuticals Inc 549300CHIMT2EUSNJB60 558868105 43569.00000000 NS USD 19076686.65000000 0.108576076783 Long EC CORP US N 1 N N N CorVel Corp N/A 221006109 93398.00000000 NS USD 8317091.90000000 0.047337214544 Long EC CORP US N 1 N N N uniQure NV 724500RPCTZLFYJZ3S98 N90064101 107485.00000000 NS USD 1755230.05000000 0.009989994393 Long EC CORP US N 1 N N N OmniAb Inc N/A 68218J103 295297.00000000 NS USD 472475.20000000 0.002689120209 Long EC CORP US N 1 N N N N/A N/A N/A 165000.00000000 NC USD 227700.00000000 0.001295967855 N/A DE N/A N 2 BANK OF AMERICA, N.A. B4TYDEB6GKMZO031MB27 N/A UNITEDHEALTH GRP Y Receive positive return on reference instrument 2026-08-31 0.00000000 USD 0.00000000 USD 50900850.00000000 USD 227700.00000000 N N N Pulse Biosciences Inc 529900NJUBI06118FM73 74587B101 60930.00000000 NS USD 946852.20000000 0.005389064624 Long EC CORP US N 1 N N Collegium Pharmaceutical Inc 54930049FXZMTLW8D496 19459J104 97860.00000000 NS USD 3796968.00000000 0.021610665241 Long EC CORP US N 1 N N N Tandem Diabetes Care Inc 549300JEPFOD0K4D3I05 875372203 201334.00000000 NS USD 2518688.34000000 0.014335261862 Long EC CORP US N 1 N N N Tyra Biosciences Inc N/A 90240B106 40190.00000000 NS USD 509207.30000000 0.002898183102 Long EC CORP US N 1 N N N Intuitive Surgical Inc 54930052SRG011710797 46120E602 1083408.00000000 NS USD 512771589.36000000 2.918469463822 Long EC CORP US N 1 N N N Dexcom Inc 549300YSK3QDSFR5EU59 252131107 1185342.00000000 NS USD 89303666.28000000 0.508277034948 Long EC CORP US N 1 N N N iRadimed Corp 549300YVHWP0YJ1YW816 46266A109 24935.00000000 NS USD 1806291.40000000 0.010280613050 Long EC CORP US N 1 N N N Cytokinetics Inc 549300BE5DY1HW7IHA64 23282W605 342323.00000000 NS USD 12094271.59000000 0.068835253463 Long EC CORP US N 1 N N N Zoetis Inc 549300HD9Q1LOC9KLJ48 98978V103 1345969.00000000 NS USD 210509551.60000000 1.198127413717 Long EC CORP US N 1 N N N PACS Group Inc N/A 69380Q107 141119.00000000 NS USD 1642625.16000000 0.009349097082 Long EC CORP US N 1 N N N Iovance Biotherapeutics Inc 2549002L8WT2ACU5Q878 462260100 811812.00000000 NS USD 1810340.76000000 0.010303660219 Long EC CORP US N 1 N N N Pulmonx Corp 549300WZMFR0ZK7RJY40 745848101 110530.00000000 NS USD 189006.30000000 0.001075740400 Long EC CORP US N 1 N N N Prestige Consumer Healthcare Inc N/A 74112D101 148641.00000000 NS USD 10113533.64000000 0.057561767680 Long EC CORP US N 1 N N N Alector Inc 549300Z8RQOIY1JMHC25 014442107 199634.00000000 NS USD 469139.90000000 0.002670137154 Long EC CORP US N 1 N N N Tenet Healthcare Corp 0W9AIBT6U6ADJ2I8HK17 88033G407 280817.00000000 NS USD 51762997.61000000 0.294612125584 Long EC CORP US N 1 N N N Agilent Technologies Inc QUIX8Y7A2WP0XRMW7G29 00846U101 858110.00000000 NS USD 107830102.60000000 0.613721329825 Long EC CORP US N 1 N N N Pennant Group Inc/The 5493007H2OYR6BYLDA64 70805E109 104619.00000000 NS USD 2511902.19000000 0.014296638093 Long EC CORP US N 1 N N N TransMedics Group Inc 549300060GVOSMWARH50 89377M109 97035.00000000 NS USD 11155143.60000000 0.063490151632 Long EC CORP US N 1 N N N EyePoint Pharmaceuticals Inc 549300QE1RU34T50MR69 30233G209 176898.00000000 NS USD 2046709.86000000 0.011648968764 Long EC CORP US N 1 N N N Arcellx Inc N/A 03940C100 83079.00000000 NS USD 5764851.81000000 0.032810990936 Long EC CORP US N 1 N N N ORIC Pharmaceuticals Inc 54930033FJRNEYBW0L25 68622P109 102973.00000000 NS USD 1053413.79000000 0.005995566140 Long EC CORP US N 1 N N N West Pharmaceutical Services Inc 5493007NKRGM1RJQ1P16 955306105 216890.00000000 NS USD 53560985.50000000 0.304845478723 Long EC CORP US N 1 N N N Alkermes PLC N/A G01767105 474554.00000000 NS USD 13747829.38000000 0.078246574248 Long EC CORP US N 1 N N N BrightSpring Health Services Inc N/A 10950A106 293055.00000000 NS USD 6942472.95000000 0.039513490467 Long EC CORP US N 1 N N N McKesson Corp 549300WZWOM80UCFSF54 58155Q103 377914.00000000 NS USD 259490868.96000000 1.476907443616 Long EC CORP US N 1 N N N Edwards Lifesciences Corp YA13X31F3V31L8TMPR58 28176E108 1773176.00000000 NS USD 144230135.84000000 0.820894245988 Long EC CORP US N 1 N N N Astrana Health Inc 5493008O4R82Q4STJ936 03763A207 135027.00000000 NS USD 4315462.92000000 0.024561709376 Long EC CORP US N 1 N N N Vericel Corp 54930076YM3PLTDR4B91 92346J108 151637.00000000 NS USD 5513521.32000000 0.031380528766 Long EC CORP US N 1 N N N Treace Medical Concepts Inc N/A 89455T109 151563.00000000 NS USD 1112472.42000000 0.006331701783 Long EC CORP US N 1 N N N Clover Health Investments Corp 5493000HLYOYQU6LK133 18914F103 1257730.00000000 NS USD 3295252.60000000 0.018755122725 Long EC CORP US N 1 N N N ADMA Biologics Inc N/A 000899104 720810.00000000 NS USD 12441180.60000000 0.070809706365 Long EC CORP US N 1 N N N OmniAb Inc N/A 68218J301 22076.00000000 NS USD 0.22000000 0.000000001252 Long EC CORP US N 3 N N N Geron Corp 549300T282D7Z2YESL90 374163103 1441612.00000000 NS USD 2018256.80000000 0.011487026510 Long EC CORP US N 1 N N N Supernus Pharmaceuticals Inc 549300GRM36VBKISYJ58 868459108 169149.00000000 NS USD 7632002.88000000 0.043437990355 Long EC CORP US N 1 N N N N/A N/A N/A 100000.00000000 NC USD 53000.00000000 0.000301652596 N/A DE N/A N 2 GOLDMAN SACHS INTERNATIONAL W22LROWP2IHZNBB6K528 N/A JOHNSON&JOHNSON Y Receive positive return on reference instrument 2026-01-30 0.00000000 USD 0.00000000 USD 17664000.00000000 USD 53000.00000000 N N N N/A N/A N/A 850000.00000000 NC USD 10565500.00000000 0.060134160627 N/A DE N/A N 2 BANK OF AMERICA, N.A. B4TYDEB6GKMZO031MB27 N/A JOHNSON&JOHNSON Y Receive positive return on reference instrument 2025-08-31 0.00000000 USD 0.00000000 USD 140029000.00000000 USD 10565500.00000000 N N N Zymeworks Inc 894500AHOYAGYLYZJL67 98985Y108 112546.00000000 NS USD 1666806.26000000 0.009486725225 Long EC CORP US N 1 N N N SI-BONE Inc 549300J8JGYVJJHV9C31 825704109 115707.00000000 NS USD 1928835.69000000 0.010978081038 Long EC CORP US N 1 N N N Humacyte Inc N/A 44486Q103 373116.00000000 NS USD 578329.80000000 0.003291597850 Long EC CORP US N 1 N N Molina Healthcare Inc 549300NQQCEQ46YHZ591 60855R100 163623.00000000 NS USD 29587947.09000000 0.168401529786 Long EC CORP US N 1 N N N Y-mAbs Therapeutics Inc N/A 984241109 95805.00000000 NS USD 819132.75000000 0.004662141911 Long EC CORP US N 1 N N N iRhythm Technologies Inc 549300FJI72RJGDQS384 450056106 96386.00000000 NS USD 16383692.28000000 0.093248741966 Long EC CORP US N 1 N N N Kura Oncology Inc 5493005QORQTZCZYOP39 50127T109 209048.00000000 NS USD 1651479.20000000 0.009399490368 Long EC CORP US N 1 N N N CONMED Corp Z6C0YCECH9DCU5ZIQW84 207410101 93547.00000000 NS USD 5085214.92000000 0.028942797863 Long EC CORP US N 1 N N N Vertex Pharmaceuticals Inc 54930015RAQRRZ5ZGJ91 92532F100 776259.00000000 NS USD 303532794.18000000 1.727574634524 Long EC CORP US N 1 N N N Danaher Corp S4BKK9OTCEWQ3YHPFM11 235851102 1947298.00000000 NS USD 400792874.36000000 2.281136064104 Long EC CORP US N 1 N N N Glaukos Corp 5299004JA1LHE21M6T14 377322102 173021.00000000 NS USD 16578872.22000000 0.094359619999 Long EC CORP US N 1 N N N Castle Biosciences Inc 2549007M2Q4HLR1XD252 14843C105 87384.00000000 NS USD 2098089.84000000 0.011941400922 Long EC CORP US N 1 N N N Cerus Corp 254900BIEY9XIDA04Q21 157085101 567898.00000000 NS USD 743946.38000000 0.004234214293 Long EC CORP US N 1 N N N ImmunityBio Inc 529900J9XLBR4HFL4B83 45256X103 799463.00000000 NS USD 1870743.42000000 0.010647445488 Long EC CORP US N 1 N N Waystar Holding Corp N/A 946784105 287282.00000000 NS USD 10882242.16000000 0.061936917139 Long EC CORP US N 1 N N N Natera Inc N/A 632307104 392154.00000000 NS USD 65979910.50000000 0.375528516040 Long EC CORP US N 1 N N N AMN Healthcare Services Inc 529900W3ARRTCNFH2I39 001744101 115728.00000000 NS USD 2404827.84000000 0.013687218173 Long EC CORP US N 1 N N N Quanterix Corp N/A 74766Q101 111373.00000000 NS USD 506747.15000000 0.002884181015 Long EC CORP US N 1 N N N Cogent Biosciences Inc N/A 19240Q201 252535.00000000 NS USD 3050622.80000000 0.017362797924 Long EC CORP US N 1 N N N Royalty Pharma PLC 549300FGFN7VOK8BZR03 G7709Q104 1146513.00000000 NS USD 41251537.74000000 0.234785537514 Long EC CORP US N 1 N N N Liquidia Corp N/A 53635D202 193460.00000000 NS USD 5354972.80000000 0.030478140600 Long EC CORP US N 1 N N N Integer Holdings Corp 549300SUD2ED5XG6X569 45826H109 105347.00000000 NS USD 11363780.89000000 0.064677622959 Long EC CORP US N 1 N N N N/A N/A N/A 150000.00000000 NC USD 1864500.00000000 0.010611910699 N/A DE N/A N 2 BANK OF AMERICA, N.A. B4TYDEB6GKMZO031MB27 N/A JOHNSON&JOHNSON Y Receive positive return on reference instrument 2025-08-31 0.00000000 USD 0.00000000 USD 24711000.00000000 USD 1864500.00000000 N N N Exact Sciences Corp 549300VM3X1FYD4N9Z14 30063P105 570548.00000000 NS USD 27055386.16000000 0.153987311267 Long EC CORP US N 1 N N N Brookdale Senior Living Inc LH7MQB13NWY7CJ9VC445 112463104 636810.00000000 NS USD 4903437.00000000 0.027908198209 Long EC CORP US N 1 N N N PTC Therapeutics Inc 549300UJLWOIWFDGB318 69366J200 215382.00000000 NS USD 10624794.06000000 0.060471636235 Long EC CORP US N 1 N N N MacroGenics Inc 5493001KJQUA83L8MH79 556099109 154610.00000000 NS USD 273659.70000000 0.001557550173 Long EC CORP US N 1 N N N Atea Pharmaceuticals Inc N/A 04683R106 180833.00000000 NS USD 607598.88000000 0.003458184529 Long EC CORP US N 1 N N N AtriCure Inc N/A 04963C209 149723.00000000 NS USD 5538253.77000000 0.031521294950 Long EC CORP US N 1 N N N Acadia Healthcare Co Inc 5493005CW985Y9D0NC11 00404A109 278283.00000000 NS USD 6389377.68000000 0.036365516418 Long EC CORP US N 1 N N N Denali Therapeutics Inc 549300ZTQ2HO18L3Q830 24823R105 416761.00000000 NS USD 6363940.47000000 0.036220739051 Long EC CORP US N 1 N N N Neumora Therapeutics Inc N/A 640979100 170728.00000000 NS USD 295359.44000000 0.001681055511 Long EC CORP US N 1 N N N Apellis Pharmaceuticals Inc 254900HS0ZFRXXSB9D42 03753U106 227731.00000000 NS USD 6278543.67000000 0.035734698174 Long EC CORP US N 1 N N N Establishment Labs Holdings Inc 549300BCBQ714JNJ7V58 G31249108 52377.00000000 NS USD 2161598.79000000 0.012302865822 Long EC CORP US N 1 N N Agios Pharmaceuticals Inc 529900ONJHY8EOGYT555 00847X104 166145.00000000 NS USD 6265327.95000000 0.035659480131 Long EC CORP US N 1 N N N IDEXX Laboratories Inc OGMTXK0LUU1HKV2P0J84 45168D104 243107.00000000 NS USD 157312108.63000000 0.895351058546 Long EC CORP US N 1 N N N Bicara Therapeutics Inc N/A 055477103 57709.00000000 NS USD 689045.46000000 0.003921742498 Long EC CORP US N 1 N N N Cooper Cos Inc/The QJKMVPIGLH7530PCUE20 216648501 602291.00000000 NS USD 40591401.95000000 0.231028336091 Long EC CORP US N 1 N N N Vera Therapeutics Inc N/A 92337R101 125133.00000000 NS USD 2707878.12000000 0.015412046550 Long EC CORP US N 1 N N N Privia Health Group Inc N/A 74276R102 296116.00000000 NS USD 6822512.64000000 0.038830729353 Long EC CORP US N 1 N N N Becton Dickinson & Co ICE2EP6D98PQUILVRZ91 075887109 866463.00000000 NS USD 167210029.74000000 0.951685654913 Long EC CORP US N 1 N N N N/A N/A N/A 300000.00000000 NC USD 6413997.00000000 0.036505638717 N/A DE N/A N 2 BANK OF AMERICA, N.A. B4TYDEB6GKMZO031MB27 N/A ABBVIE INC Y Receive positive return on reference instrument 2025-08-31 0.00000000 USD 0.00000000 USD 56706000.00000000 USD 6413997.00000000 N N N Alnylam Pharmaceuticals Inc 529900S3ZI14OWRJII50 02043Q107 394138.00000000 NS USD 175986558.38000000 1.001637780510 Long EC CORP US N 1 N N N Intellia Therapeutics Inc 5493002T5BCPE5DZC723 45826J105 297663.00000000 NS USD 3379963.37000000 0.019237259023 Long EC CORP US N 1 N N N Multiplan Corp N/A 62548M209 12401.00000000 NS USD 854552.91000000 0.004863737821 Long EC CORP US N 1 N N N DocGo Inc N/A 256086109 260852.00000000 NS USD 406929.12000000 0.002316060864 Long EC CORP US N 1 N N N Vaxcyte Inc 254900M7NMHTGASX8D95 92243G108 351239.00000000 NS USD 10814648.81000000 0.061552205638 Long EC CORP US N 1 N N N Novocure Ltd 213800YPP55UMHWA4826 G6674U108 319829.00000000 NS USD 3943491.57000000 0.022444612702 Long EC CORP US N 1 N N N CVS Health Corp 549300EJG376EN5NQE29 126650100 3823871.00000000 NS USD 279716163.65000000 1.592020890176 Long EC CORP US N 1 N N N Ideaya Biosciences Inc 549300ULW08F62IJML11 45166A102 238763.00000000 NS USD 5861631.65000000 0.033361819050 Long EC CORP US N 1 N N N Cassava Sciences Inc 529900XA0UG5JXABYF08 14817C107 132935.00000000 NS USD 303091.80000000 0.001725064690 Long EC CORP US N 1 N N N Lexicon Pharmaceuticals Inc N/A 528872302 547608.00000000 NS USD 602368.80000000 0.003428417223 Long EC CORP US N 1 N N N Axogen Inc N/A 05463X106 130617.00000000 NS USD 2108158.38000000 0.011998706606 Long EC CORP US N 1 N N N Corcept Therapeutics Inc 529900EO9LUTFMZ7FF90 218352102 288870.00000000 NS USD 20140016.40000000 0.114628080189 Long EC CORP US N 1 N N N Mineralys Therapeutics Inc N/A 603170101 108272.00000000 NS USD 1676050.56000000 0.009539339699 Long EC CORP US N 1 N N N Beam Therapeutics Inc N/A 07373V105 274107.00000000 NS USD 4484390.52000000 0.025523170682 Long EC CORP US N 1 N N N Universal Health Services Inc 549300YGMGQDO0NMJD09 913903100 172961.00000000 NS USD 31406258.38000000 0.178750554743 Long EC CORP US N 1 N N N Janux Therapeutics Inc N/A 47103J105 116148.00000000 NS USD 2638882.56000000 0.015019354289 Long EC CORP US N 1 N N N Pacira BioSciences Inc N/A 695127100 140010.00000000 NS USD 3734066.70000000 0.021252658817 Long EC CORP US N 1 N N N GRAIL Inc 2549009XSNESW3VE8024 384747101 92337.00000000 NS USD 3027730.23000000 0.017232503524 Long EC CORP US N 1 N N HealthStream Inc 529900OJ88H8635JNH64 42222N103 74253.00000000 NS USD 2085024.24000000 0.011867037296 Long EC CORP US N 1 N N N Veeva Systems Inc 549300YZEXPDB92M2F02 922475108 469320.00000000 NS USD 126340944.00000000 0.719076865305 Long EC CORP US N 1 N N N Xenon Pharmaceuticals Inc 549300XV44Q9Z1MIPQ03 98420N105 197288.00000000 NS USD 7637018.48000000 0.043466536935 Long EC CORP US N 1 N N N Centene Corp 549300Z7JJ4TQSQGT333 15135B101 1504906.00000000 NS USD 43702470.24000000 0.248735163054 Long EC CORP US N 1 N N N Altimmune Inc 549300EOYCQ8SW3NVE64 02155H200 247490.00000000 NS USD 947886.70000000 0.005394952541 Long EC CORP US N 1 N N Guardant Health Inc 254900M8C3E5VC8BR186 40131M109 337411.00000000 NS USD 22748249.62000000 0.129472991969 Long EC CORP US N 1 N N N Viridian Therapeutics Inc 549300C775BNYF550E70 92790C104 172854.00000000 NS USD 3177056.52000000 0.018082402829 Long EC CORP US N 1 N N N Moderna Inc 549300EI6OKH5K5Q2G38 60770K107 1052814.00000000 NS USD 25362289.26000000 0.144350951327 Long EC CORP US N 1 N N N Cardinal Health Inc CCU46N3GJMF4OK4N7U60 14149Y108 721010.00000000 NS USD 107271867.80000000 0.610544103842 Long EC CORP US N 1 N N N Viatris Inc 254900ZZTSW7NL773X71 92556V106 3543047.00000000 NS USD 37379145.85000000 0.212745592795 Long EC CORP US N 1 N N N STERIS PLC N/A G8473T100 297457.00000000 NS USD 72894812.42000000 0.414885084379 Long EC CORP US N 1 N N N Select Medical Holdings Corp N/A 81619Q105 347942.00000000 NS USD 4526725.42000000 0.025764122239 Long EC CORP US N 1 N N N RxSight Inc N/A 78349D107 104447.00000000 NS USD 944200.88000000 0.005373974481 Long EC CORP US N 1 N N N Mettler-Toledo International Inc 5493000BD5GJNUDIUG10 592688105 62742.00000000 NS USD 81629851.68000000 0.464601070745 Long EC CORP US N 1 N N N Bio-Techne Corp 54930073RLKQ51TILZ35 09073M104 473296.00000000 NS USD 25856160.48000000 0.147161848234 Long EC CORP US N 1 N N N Definitive Healthcare Corp N/A 24477E103 113189.00000000 NS USD 456151.67000000 0.002596213884 Long EC CORP US N 1 N N N Ginkgo Bioworks Holdings Inc N/A 37611X209 90009.00000000 NS USD 1140414.03000000 0.006490733089 Long EC CORP US N 1 N N N Ocular Therapeutix Inc 529900ABAWFXOHSIHG03 67576A100 312814.00000000 NS USD 3819458.94000000 0.021738673740 Long EC CORP US N 1 N N N Insmed Inc 529900Q55QAG41CCAC11 457669307 574204.00000000 NS USD 78149164.40000000 0.444790535702 Long EC CORP US N 1 N N N Humana Inc 529900YLDW34GJAO4J06 444859102 364858.00000000 NS USD 110792780.28000000 0.630583582960 Long EC CORP US N 1 N N N Syndax Pharmaceuticals Inc 529900OF94TRHKZVBS87 87164F105 246738.00000000 NS USD 4029231.54000000 0.022932606751 Long EC CORP US N 1 N N N ALX Oncology Holdings Inc N/A 00166B105 76537.00000000 NS USD 89548.29000000 0.000509669325 Long EC CORP US N 1 N N N MannKind Corp 213800GFBCNY1ZFST722 56400P706 873319.00000000 NS USD 4008534.21000000 0.022814806688 Long EC CORP US N 1 N N N Fortrea Holdings Inc 5493000FIVFABOVCDU97 34965K107 273184.00000000 NS USD 2690862.40000000 0.015315200585 Long EC CORP US N 1 N N N Gilead Sciences Inc 549300WTZWR07K8MNV44 375558103 3760027.00000000 NS USD 424770250.19000000 2.417604699720 Long EC CORP US N 1 N N N Travere Therapeutics Inc N/A 89422G107 255120.00000000 NS USD 4464600.00000000 0.025410531781 Long EC CORP US N 1 N N N ICU Medical Inc 5493003NRW7LS2QZRH60 44930G107 70843.00000000 NS USD 9043817.38000000 0.051473415079 Long EC CORP US N 1 N N N UFP Technologies Inc 549300RJ8LY41HS70C91 902673102 22105.00000000 NS USD 4645586.80000000 0.026440628729 Long EC CORP US N 1 N N N Merus NV 549300W8GPUWU8QNU293 N5749R100 157407.00000000 NS USD 10363676.88000000 0.058985472547 Long EC CORP US N 1 N N N UnitedHealth Group Inc 549300GHBMY8T5GXDE41 91324P102 2577053.00000000 NS USD 798551413.11000000 4.545002029778 Long EC CORP US N 1 N N N Annexon Inc N/A 03589W102 211678.00000000 NS USD 436056.68000000 0.002481842074 Long EC CORP US N 1 N N N Concentra Group Holdings Parent Inc N/A 20603L102 348032.00000000 NS USD 8283161.60000000 0.047144098259 Long EC CORP US N 1 N N N Talkspace Inc N/A 87427V103 433914.00000000 NS USD 1154211.24000000 0.006569260716 Long EC CORP US N 1 N N N Novavax Inc 529900J4GJHPEPQ23205 670002401 437530.00000000 NS USD 3268349.10000000 0.018601999883 Long EC CORP US N 1 N N Rapport Therapeutics Inc N/A 75383L102 49793.00000000 NS USD 877850.59000000 0.004996337928 Long EC CORP US N 1 N N N Viking Therapeutics Inc 529900IVC72YPFA25M37 92686J106 322428.00000000 NS USD 8721677.40000000 0.049639936559 Long EC CORP US N 1 N N Ironwood Pharmaceuticals Inc 549300PC8MR6QHH6P296 46333X108 438816.00000000 NS USD 579237.12000000 0.003296761915 Long EC CORP US N 1 N N N Cross Country Healthcare Inc 54930037L0NBIPZ5S663 227483104 88549.00000000 NS USD 1184785.62000000 0.006743276587 Long EC CORP US N 1 N N N N/A N/A N/A 100000.00000000 NC USD 864000.00000000 0.004917506486 N/A DE N/A N 2 BANK OF AMERICA, N.A. B4TYDEB6GKMZO031MB27 N/A GLOBUS MEDICAL I Y Receive positive return on reference instrument 2025-08-31 0.00000000 USD 0.00000000 USD 5263000.00000000 USD 864000.00000000 N N N Repligen Corp 54930006QJ0T5AUO1E71 759916109 161547.00000000 NS USD 19760429.04000000 0.112467636549 Long EC CORP US N 1 N N N Lyell Immunopharma Inc N/A 55083R203 15946.00000000 NS USD 176681.68000000 0.001005594105 Long EC CORP US N 1 N N N Aurinia Pharmaceuticals Inc 5299008YP2BW4570ML28 05156V102 346870.00000000 NS USD 4158971.30000000 0.023671028176 Long EC CORP US N 1 N N N LeMaitre Vascular Inc 549300FZUBUB7MHY8R17 525558201 64811.00000000 NS USD 6180701.02000000 0.035177821014 Long EC CORP US N 1 N N N Neogen Corp 549300HJT9FC36N4UW43 640491106 623789.00000000 NS USD 3586786.75000000 0.020414406375 Long EC CORP US N 1 N N N Alphatec Holdings Inc 549300EZE8CQ8K65FS24 02081G201 353055.00000000 NS USD 5613574.50000000 0.031949987286 Long EC CORP US N 1 N N N Cencora Inc AI8GXW8LG5WK7E9UD086 03073E105 556580.00000000 NS USD 162304293.80000000 0.923764372152 Long EC CORP US N 1 N N N Insulet Corp 549300TZTYD2PYN92D43 45784P101 212751.00000000 NS USD 72309809.88000000 0.411555508239 Long EC CORP US N 1 N N N Vir Biotechnology Inc N/A 92764N102 270335.00000000 NS USD 1335454.90000000 0.007600819598 Long EC CORP US N 1 N N N Johnson & Johnson 549300G0CFPGEF6X2043 478160104 5022852.00000000 NS USD 889898688.84000000 5.064910387326 Long EC CORP US N 1 N N N Merit Medical Systems Inc 549300OYTY138SP2CE83 589889104 178632.00000000 NS USD 16173341.28000000 0.092051516958 Long EC CORP US N 1 N N N Bio-Rad Laboratories Inc 549300ZC1GPV35XYDK53 090572207 56819.00000000 NS USD 16925243.72000000 0.096331013631 Long EC CORP US N 1 N N N Integra LifeSciences Holdings Corp WB7IJCYY8YFTENS4O147 457985208 199378.00000000 NS USD 3016589.14000000 0.017169093359 Long EC CORP US N 1 N N N OrthoPediatrics Corp 5493000KUTPFGOPAT717 68752L100 47875.00000000 NS USD 1022610.00000000 0.005820244569 Long EC CORP US N 1 N N N Schrodinger Inc/United States 984500044BAE4791E559 80810D103 194539.00000000 NS USD 3795455.89000000 0.021602058979 Long EC CORP US N 1 N N N Monte Rosa Therapeutics Inc N/A 61225M102 111401.00000000 NS USD 534724.80000000 0.003043417444 Long EC CORP US N 1 N N N MoonLake Immunotherapeutics N/A 61559X104 67588.00000000 NS USD 3768031.00000000 0.021445968615 Long EC CORP US N 1 N N N Arcturus Therapeutics Holdings Inc N/A 03969T109 73713.00000000 NS USD 1253858.13000000 0.007136406814 Long EC CORP US N 1 N N N Amneal Pharmaceuticals Inc N/A 03168L105 474603.00000000 NS USD 4537204.68000000 0.025823765560 Long EC CORP US N 1 N N N REGENXBIO Inc 549300EOES47LATSET33 75901B107 127615.00000000 NS USD 1139601.95000000 0.006486111089 Long EC CORP US N 1 N N N Phathom Pharmaceuticals Inc N/A 71722W107 126563.00000000 NS USD 1541537.34000000 0.008773749847 Long EC CORP US N 1 N N Chinook Therapeutics Inc 549300X0O3003W5QYQ48 N/A 784.00000000 NS USD 0.00000000 0.000000 Long EC CORP US N 3 N N N ArriVent Biopharma Inc N/A 04272N102 55417.00000000 NS USD 1059573.04000000 0.006030621871 Long EC CORP US N 1 N N N Fulgent Genetics Inc 549300CL6P01M68QJ404 359664109 59681.00000000 NS USD 1323127.77000000 0.007530659017 Long EC CORP US N 1 N N N Masimo Corp 549300Q4A8JK0PIYCU29 574795100 139485.00000000 NS USD 19487449.35000000 0.110913956693 Long EC CORP US N 1 N N N Dynavax Technologies Corp 549300T5URIXWDILX594 268158201 290298.00000000 NS USD 2937815.76000000 0.016720750064 Long EC CORP US N 1 N N N Labcorp Holdings Inc N/A 504922105 253060.00000000 NS USD 70348149.40000000 0.400390602990 Long EC CORP US N 1 N N N REVOLUTION Medicines Inc 549300JU3X0LBCQ65892 76155X100 422259.00000000 NS USD 16033174.23000000 0.091253748002 Long EC CORP US N 1 N N N Tilray Brands Inc 549300Y4V60733TO1478 88688T100 3133675.00000000 NS USD 4324471.50000000 0.024612982235 Long EC CORP US N 1 N N Omnicell Inc 5493008RH0GTKHHPZI77 68213N109 141783.00000000 NS USD 4620707.97000000 0.026299029414 Long EC CORP US N 1 N N N 2025-10-28 VANGUARD WORLD FUND Ashley Grim Ashley Grim Treasurer