<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0306</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2014-04-30</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0001500096</issuerCik>
        <issuerName>KAYNE ANDERSON MIDSTREAM/ENERGY FUND, INC.</issuerName>
        <issuerTradingSymbol>KMF</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0000005272</rptOwnerCik>
            <rptOwnerName>AMERICAN INTERNATIONAL GROUP INC</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>175 WATER STREET</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>NEW YORK</rptOwnerCity>
            <rptOwnerState>NY</rptOwnerState>
            <rptOwnerZipCode>10038</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>1</isOther>
            <otherText>See General Remarks</otherText>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>3.46% Series E Senior Unsecured Notes due July 30, 2021</value>
            </securityTitle>
            <transactionDate>
                <value>2014-04-30</value>
            </transactionDate>
            <deemedExecutionDate></deemedExecutionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>P</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionTimeliness>
                <value></value>
            </transactionTimeliness>
            <transactionAmounts>
                <transactionShares>
                    <value>15000000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>15000000.00</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <valueOwnedFollowingTransaction>
                    <value>44000000.00</value>
                </valueOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>Held through subsidiaries</value>
                    <footnoteId id="F1"/>
                    <footnoteId id="F2"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Series C Mandatory Redeemable Preferred Shares</value>
            </securityTitle>
            <transactionDate>
                <value>2014-04-30</value>
            </transactionDate>
            <deemedExecutionDate></deemedExecutionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>P</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionTimeliness>
                <value></value>
            </transactionTimeliness>
            <transactionAmounts>
                <transactionShares>
                    <value>1200000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>25.00</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>1200000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>I</value>
                </directOrIndirectOwnership>
                <natureOfOwnership>
                    <value>Held through subsidiaries</value>
                    <footnoteId id="F3"/>
                </natureOfOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">The United States Life Insurance Company in the City of New York, American Home Assurance Company and  United Guaranty Mortgage Insurance Company, each an indirectly wholly owned subsidiary of American International Group, Inc. (&quot;AIG&quot;), directly hold $9,875,000 principal amount, $4,875,000 principal amount and $250,000 principal amount, respectively, of the 3.46% Series E Senior Unsecured Notes due July 30, 2021.  As previously reported, The Variable Annuity Life Insurance Company and AIG Specialty Insurance Company, each an indirectly wholly owned subsidiary of AIG, directly hold $6,000,000 principal amount and $4,000,000 principal amount, respectively, of the Issuer's 4.00% Series C Senior Unsecured Notes due March 22, 2022.</footnote>
        <footnote id="F2">Also, as previously reported, The United States Life Insurance Company in the City of New York (as successor by merger to First SunAmerica Life Insurance Company), an indirectly wholly owned subsidiary of AIG, directly holds $10,000,000 principal amount of the Issuer's 3.93% Series A Senior Unsecured Notes due March 3, 2016, and American General Life Insurance Company (as successor by merger to SunAmerica Annuity and Life Assurance Company), an indirectly wholly owned subsidiary of AIG, directly holds $9,000,000 principal amount of the Issuer's 4.62% Series B Senior Unsecured Notes due March 3, 2018.  AIG is an indirect beneficial owner of such senior debt securities.</footnote>
        <footnote id="F3">The Series C Mandatory Redeemable Preferred Shares are held directly by American General Life Insurance Company, American Home Assurance Company and United Guaranty Mortgage Insurance Company, each an indirectly wholly owned subsidiary of AIG. As previously reported, the Issuer's Series B Mandatory Redeemable Preferred Shares are held directly by The Variable Annuity Life Insurance Company, an indirectly wholly owned subsidiary of AIG.  AIG is an indirect beneficial owner of the Series C Mandatory Redeemable Preferred Shares and the Series B Mandatory Redeemable Preferred Shares.</footnote>
    </footnotes>

    <remarks>Filed pursuant to Section 30(h) of the Investment Company Act of 1940.  The referenced securities are senior debt securities and preferred equity securities which the Reporting Person is informed, represent, in the aggregate, in excess of 10% of the senior debt securities and preferred equity securities of the Issuer, respectively.</remarks>

    <ownerSignature>
        <signatureName>/s/ Brian T. Schreiber, Authorized Person</signatureName>
        <signatureDate>2014-05-02</signatureDate>
    </ownerSignature>
</ownershipDocument>
