<?xml version="1.0" encoding="UTF-8"?><edgarSubmission xmlns="http://www.sec.gov/edgar/nport" xmlns:com="http://www.sec.gov/edgar/common" xmlns:ncom="http://www.sec.gov/edgar/nportcommon" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xsi:schemaLocation="http://www.sec.gov/edgar/nport eis_NPORT_Filer.xsd">
  <headerData>
    <submissionType>NPORT-P</submissionType>
    <isConfidential>false</isConfidential>
    <filerInfo>

      <filer>
        <issuerCredentials>
          <cik>0000052136</cik>
          <ccc>XXXXXXXX</ccc>
        </issuerCredentials>
      </filer>


      <seriesClassInfo>
        <seriesId>S000042166</seriesId>
        <classId>C000130929</classId>
        <classId>C000130927</classId>
        <classId>C000130928</classId>
      </seriesClassInfo>


    </filerInfo>
  </headerData>
  <formData>
    <genInfo>
      <regName>Natixis Funds Trust II</regName>
      <regFileNumber>811-00242</regFileNumber>
      <regCik>0000052136</regCik>
      <regLei>R4B5ZXLI2IMIOWT67V76</regLei>
      <regStreet1>888 BOYLSTON STREET</regStreet1>
      <regStreet2>Suite 800</regStreet2>
      <regCity>BOSTON</regCity>
      <regStateConditional regCountry="US" regState="US-MA"/>
      <regZipOrPostalCode>02199-8197</regZipOrPostalCode>
      <regPhone>617-449-2822</regPhone>
      <seriesName>AlphaSimplex Tactical U.S. Market Fund</seriesName>
      <seriesId>S000042166</seriesId>
      <seriesLei>549300GVIL1EOIRQEV34</seriesLei>
      <repPdEnd>2020-12-31</repPdEnd>
      <repPdDate>2020-09-30</repPdDate>
      <isFinalFiling>Y</isFinalFiling>
    </genInfo>
    <fundInfo>
      <totAssets>22467331.84</totAssets>
      <totLiabs>175069.28</totLiabs>
      <netAssets>22292262.56</netAssets>
      <assetsAttrMiscSec>0.00000000</assetsAttrMiscSec>
      <assetsInvested>0.00000000</assetsInvested>
      <amtPayOneYrBanksBorr>0.00000000</amtPayOneYrBanksBorr>
      <amtPayOneYrCtrldComp>0.00000000</amtPayOneYrCtrldComp>
      <amtPayOneYrOthAffil>0.00000000</amtPayOneYrOthAffil>
      <amtPayOneYrOther>0.00000000</amtPayOneYrOther>
      <amtPayAftOneYrBanksBorr>0.00000000</amtPayAftOneYrBanksBorr>
      <amtPayAftOneYrCtrldComp>0.00000000</amtPayAftOneYrCtrldComp>
      <amtPayAftOneYrOthAffil>0.00000000</amtPayAftOneYrOthAffil>
      <amtPayAftOneYrOther>0.00000000</amtPayAftOneYrOther>
      <delayDeliv>0.00000000</delayDeliv>
      <standByCommit>0.00000000</standByCommit>
      <liquidPref>0.00000000</liquidPref>
      <cshNotRptdInCorD>1970713.77000000</cshNotRptdInCorD>
      <isNonCashCollateral>N</isNonCashCollateral>
      <returnInfo>
        <monthlyTotReturns>
          <monthlyTotReturn classId="C000130928" rtn1="4.19000000" rtn2="6.92000000" rtn3="-8.45000000"/>
          <monthlyTotReturn classId="C000130927" rtn1="4.19000000" rtn2="6.96000000" rtn3="-8.36000000"/>
          <monthlyTotReturn classId="C000130929" rtn1="4.25000000" rtn2="7.01000000" rtn3="-8.32000000"/>
        </monthlyTotReturns>
        <monthlyReturnCats>
          <equityContracts>
            <mon1 netRealizedGain="196437.50000000" netUnrealizedAppr="-407440.00000000"/>
            <mon2 netRealizedGain="401612.50000000" netUnrealizedAppr="1905170.00000000"/>
            <mon3 netRealizedGain="-763257.50000000" netUnrealizedAppr="-2079482.50000000"/>
            <futureCategory>
              <instrMon1 netRealizedGain="196437.50000000" netUnrealizedAppr="-407440.00000000"/>
              <instrMon2 netRealizedGain="401612.50000000" netUnrealizedAppr="1905170.00000000"/>
              <instrMon3 netRealizedGain="-763257.50000000" netUnrealizedAppr="-2079482.50000000"/>
            </futureCategory>
          </equityContracts>
        </monthlyReturnCats>
        <othMon1 netRealizedGain="-30178.18000000" netUnrealizedAppr="5593836.46000000"/>
        <othMon2 netRealizedGain="13008001.32000000" netUnrealizedAppr="-6989781.56000000"/>
        <othMon3 netRealizedGain="28834451.36000000" netUnrealizedAppr="-32285339.39000000"/>
      </returnInfo>
      <mon1Flow redemption="7730582.50000000" reinvestment="0.00000000" sales="1833065.72000000"/>
      <mon2Flow redemption="15041015.37000000" reinvestment="0.00000000" sales="1415775.14000000"/>
      <mon3Flow redemption="94592002.12000000" reinvestment="14579070.27000000" sales="510660.14000000"/>


    </fundInfo>
    <invstOrSecs>
      <invstOrSec>
        <name>SUMITOMO MITSUI TRUST NY</name>
        <lei>N/A</lei>
        <title>SUMITOMO MITSUI TRUST NY</title>
        <cusip>86564GJT9</cusip>
        <identifiers>
          <other otherDesc="CUSIP" value="86564GJT9"/>
        </identifiers>
        <balance>1000000.00000000</balance>
        <units>PA</units>
        <curCd>USD</curCd>
        <valUSD>999996.83000000</valUSD>
        <pctVal>4.485847173693</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>STIV</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>JP</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <debtSec>
          <maturityDt>2020-10-06</maturityDt>
          <couponKind>Fixed</couponKind>
          <annualizedRt>0.09000000</annualizedRt>
          <isDefault>N</isDefault>
          <areIntrstPmntsInArrs>N</areIntrstPmntsInArrs>
          <isPaidKind>N</isPaidKind>
        </debtSec>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>DNB NOR BK ASA</name>
        <lei>549300GKFG0RYRRQ1414</lei>
        <title>DNB NOR BK ASA</title>
        <cusip>23341VW31</cusip>
        <identifiers>
          <other otherDesc="CUSIP" value="23341VW31"/>
        </identifiers>
        <balance>1000000.00000000</balance>
        <units>PA</units>
        <curCd>USD</curCd>
        <valUSD>999995.56000000</valUSD>
        <pctVal>4.485841476649</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>STIV</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>NO</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <debtSec>
          <maturityDt>2020-10-08</maturityDt>
          <couponKind>Fixed</couponKind>
          <annualizedRt>0.08000000</annualizedRt>
          <isDefault>N</isDefault>
          <areIntrstPmntsInArrs>N</areIntrstPmntsInArrs>
          <isPaidKind>N</isPaidKind>
        </debtSec>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>FIXED INC CLEARING CORP.REPO</name>
        <lei>549300H47WTHXPU08X20</lei>
        <title>FIXED INC CLEARING CORP.REPO</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal Identifier" value="85748R009"/>
        </identifiers>
        <balance>17551501.58000000</balance>
        <units>PA</units>
        <curCd>USD</curCd>
        <valUSD>17551501.58000000</valUSD>
        <pctVal>78.73360334223</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>RA</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <repurchaseAgrmt>
          <transCat>Repurchase</transCat>
          <clearedCentCparty centralCounterparty="FIXED INC CLEARING CORP.REPO" isCleared="Y"/>
          <isTriParty>N</isTriParty>
          <repurchaseRt>0.00000000</repurchaseRt>
          <maturityDt>2020-10-01</maturityDt>
          <repurchaseCollaterals>
            <repurchaseCollateral>
              <principalAmt>17922500.00000000</principalAmt>
              <principalCd>USD</principalCd>
              <collateralVal>17902588.10250000</collateralVal>
              <collateralCd>USD</collateralCd>
              <invstCat>UST</invstCat>
            </repurchaseCollateral>
          </repurchaseCollaterals>
        </repurchaseAgrmt>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Chicago Mercantile Exchange</name>
        <lei>SNZ2OJLFK8MNNCLQOF39</lei>
        <title>S+P500 EMINI FUT  DEC20 XCME 20201218</title>
        <cusip>000000000</cusip>
        <identifiers>
          <other otherDesc="Internal Identifier" value="ADI1FRJ70"/>
        </identifiers>
        <balance>134.00000000</balance>
        <units>NC</units>
        <curCd>USD</curCd>
        <valUSD>-55312.50000000</valUSD>
        <pctVal>-0.24812420834</pctVal>
        <payoffProfile>N/A</payoffProfile>
        <assetCat>DE</assetCat>
        <issuerConditional desc="derivative" issuerCat="OTHER"/>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <derivativeInfo>
          <futrDeriv derivCat="FUT">
            <counterparties>
              <counterpartyName>Chicago Mercantile Exchange</counterpartyName>
              <counterpartyLei>SNZ2OJLFK8MNNCLQOF39</counterpartyLei>
            </counterparties>
            <payOffProf>Long</payOffProf>
            <descRefInstrmnt>
              <indexBasketInfo>
                <indexName>E-mini S&amp;P 500 Index</indexName>
                <indexIdentifier>ESZ0 Index</indexIdentifier>
              </indexBasketInfo>
            </descRefInstrmnt>
            <expDate>2020-12-18</expDate>
            <notionalAmt>22513712.50000000</notionalAmt>
            <curCd>USD</curCd>
            <unrealizedAppr>-55312.50000000</unrealizedAppr>
          </futrDeriv>
        </derivativeInfo>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Cooperatieve Rabobank UA/NY</name>
        <lei>DG3RU1DBUFHT4ZF9WN62</lei>
        <title>Cooperatieve Rabobank UA/NY</title>
        <cusip>21687AK69</cusip>
        <identifiers>
          <other otherDesc="CUSIP" value="21687AK69"/>
        </identifiers>
        <balance>1000000.00000000</balance>
        <units>PA</units>
        <curCd>USD</curCd>
        <valUSD>999983.83000000</valUSD>
        <pctVal>4.485788857494</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>STIV</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <debtSec>
          <maturityDt>2020-10-06</maturityDt>
          <couponKind>None</couponKind>
          <annualizedRt>0.00000000</annualizedRt>
          <isDefault>N</isDefault>
          <areIntrstPmntsInArrs>N</areIntrstPmntsInArrs>
          <isPaidKind>N</isPaidKind>
        </debtSec>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
    </invstOrSecs>
    <explntrNotes>
      <explntrNote note="Futures contracts value is represented by unrealized appreciation/depreciation." noteItem="C.2.c"/>
      <explntrNote note="Monthly returns presented in Item B.5(a) have been calculated without deducting any applicable sales loads or redemption fees." noteItem="B.5.a"/>
    </explntrNotes>
    <signature>
      <ncom:dateSigned>2020-10-28</ncom:dateSigned>
      <ncom:nameOfApplicant>Natixis Funds Trust II</ncom:nameOfApplicant>
      <ncom:signature>John Sgroi</ncom:signature>
      <ncom:signerName>John Sgroi</ncom:signerName>
      <ncom:title>Assistant Treasurer</ncom:title>
    </signature>
  </formData>
  <documents>XXXX</documents>
</edgarSubmission>
