February 25, 2010

Securities and Exchange Commission
100 F Street, N.E.
Washington, D.C. 20549

                    Re: Van Kampen Exchange Fund
                        Amendment No. 35
                        to the Registration Statement on Form
                        N-1A (File No. 811-2611)

Ladies and Gentlemen:

        Van Kampen Exchange Fund (the "Registrant") hereby files via EDGAR one
electronically signed copy of Amendment No. 35 to the Registration Statement on
Form N-1A (the "Registration Statement"), complete with exhibits filed therewith
(the "Exhibits"). The Registration Statement and Exhibits thereto are filed
pursuant to Rule 8b-16 of the General Rules and Regulations (the "1940 Act
Rules") of the Securities and Exchange Commission (the "Commission") promulgated
under the Investment Company Act of 1940, as amended. The purpose of this filing
is to amend the Registrant's Prospectus to conform to the new requirements of
Form N-1A.

        Should the staff have any questions regarding the foregoing, please call
Kim Lombardo at (312) 407-0768 or Elisa Mitchell at (630) 684-6724.

                                                Very truly yours,

                                            /s/ Charles B. Taylor
                                            ----------------------
                                                Charles B. Taylor