INCOME TAXES - Reconciliation of U.S. Federal Statutory Income Tax Rate to Actual Income Tax Rate (Details) - USD ($) $ in Millions	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Amount
U.S. federal statutory income tax rate	$ 297	$ (773)	$ 1,254
Tax on global activities including exports	342	155	(47)
U.S. business credits	(246)	(189)	(169)
Debt tender and related valuation allowances	30	940	0
Deductible stock and restructuring losses	0	(583)	(203)
Sale of Biopharma business	(13)	(5)	(1,447)
Goodwill impairments	0	0	184
All other – net	66	169	(59)
Total income tax reconciliation items	179	487	(1,741)
Total	$ 476	$ (286)	$ (487)
Rate
U.S. federal statutory income tax rate	21.00%	21.00%	21.00%
Tax on global activities including exports	24.20%	(4.20%)	(0.80%)
U.S. business credits	(17.40%)	5.10%	(2.80%)
Debt tender and related valuation allowances	2.10%	(25.50%)	0.00%
Deductible stock and restructuring losses	0.00%	15.80%	(3.40%)
Sale of Biopharma business	(0.90%)	0.10%	(24.20%)
Goodwill impairments	0.00%	0.00%	3.10%
All other – net	4.70%	(4.50%)	(1.10%)
Total income tax reconciliation items	12.70%	(13.20%)	(29.20%)
Actual income tax rate	33.70%	7.80%	(8.20%)
Tax reconciliation related to separation income tax costs	$ 134
Tax reconciliation related to repatriation of earnings		$ 66
Tax reconciliation related to resolution of IRS audit			$ (140)