UNITED STATES
SECURITIES AND EXCHANGE COMMISSION
Washington, D.C. 20549
FORM N-Q
QUARTERLY SCHEDULE OF PORTFOLIO HOLDINGS OF REGISTERED
MANAGEMENT INVESTMENT COMPANIES
Investment Company Act file number 811- 3392
John Hancock Series Trust
(Exact name of registrant as specified in charter)
601 Congress Street, Boston, Massachusetts 02210
(Address of principal executive offices) (Zip code)
Michael J. Leary
Treasurer
601 Congress Street
Boston, Massachusetts 02210
(Name and address of agent for service)
	Registrant's telephone number, including area code: 617-663-4490
	Date of fiscal year end:	October 31
	Date of reporting period:	July 31, 2009

ITEM 1. SCHEDULE OF INVESTMENTS

John Hancock Mid Cap Equity Fund
Securities owned by the Fund on
July 31, 2009 (Unaudited)

	Shares	Value
Common stocks 97.42%		$21,437,197
(Cost $20,670,178)
Air Freight & Logistics 0.95%		208,500
Expeditors International Washington, Inc.	6,145	208,500
Airlines 2.70%		593,664
Copa Holdings SA (Class A)	10,418	422,346
JetBlue Airways Corp. (I)(L)	33,526	171,318
Apparel Retail 0.98%		214,806
Ross Stores, Inc.	4,872	214,806
Application Software 4.27%		939,379
Concur Technologies, Inc. (I)	16,373	564,705
Salesforce.com, Inc. (I)(L)	8,645	374,674
Asset Management & Custody Banks 2.12%		467,470
Eaton Vance Corp.	3,947	112,963
SEI Investments Co.	18,757	354,507
Automotive Retail 1.82%		400,927
Carmax, Inc. (I)(L)	18,791	303,099
O'Reilly Automotive, Inc. (I)	2,406	97,828
Biotechnology 3.77%		829,468
BioMarin Pharmaceutical, Inc. (I)	16,464	270,174
Onyx Pharmaceuticals, Inc. (I)	6,055	217,496
United Therapeutics Corp.	2,300	213,026
Vertex Pharmaceuticals, Inc. (I)	3,576	128,772
Casinos & Gaming 5.20%		1,143,727
Bally Technologies, Inc. (I)	14,160	512,734
Penn National Gaming, Inc. (I)	15,130	479,772
WMS Industries, Inc. (I)	4,182	151,221
Coal & Consumable Fuels 1.26%		277,406
Alpha Natural Resources, Inc. (I)(L)	8,328	277,406
Commodity Chemicals 1.01%		222,048
Celanese Corp. Series A	8,640	222,048
Communications Equipment 0.97%		214,426
CommScope, Inc.	8,376	214,426
Computer & Electronics Retail 1.74%		383,119
GameStop Corp. (Class A) (I)	17,502	383,119
Computer Storage & Peripherals 1.34%		294,246
Seagate Technology	24,439	294,246
Data Processing & Outsourced Services 1.61%		355,197
Euronet Worldwide, Inc. (I)	16,882	355,197
Diversified Chemicals 1.01%		221,458
FMC Corp.	4,553	221,458
Education Services 1.55%		341,167
Devry, Inc.	6,859	341,167

Page 1 

John Hancock Mid Cap Equity Fund
Securities owned by the Fund on
July 31, 2009 (Unaudited)

	Shares	Value
Electronic Components 1.94%		427,180
Amphenol Corp. (Class A)	12,809	427,180
Electronic Equipment & Instruments 0.90%		197,776
Itron, Inc. (I)	3,791	197,776
Fertilizers & Agricultural Chemicals 0.47%		102,306
CF Industries Holdings, Inc.	1,296	102,306
Health Care Equipment 5.63%		1,237,788
Hologic, Inc. (I)	12,585	184,874
ResMed, Inc. (I)	6,260	256,660
St. Jude Medical, Inc. (I)	5,228	197,148
Thoratec Corp. (I)	11,736	295,043
Varian Medical Systems, Inc. (I)	8,621	304,063
Health Care Facilities 1.05%		230,670
Psychiatric Solutions, Inc. (I)	8,537	230,670
Health Care Supplies 1.95%		429,811
Inverness Medical Innovations, Inc. (I)	12,773	429,811
Home Entertainment Software 0.85%		187,948
Electronic Arts, Inc. (I)	8,754	187,948
Household Products 0.88%		194,398
Church & Dwight Co., Inc.	3,296	194,398
Independent Power Producers & Energy Traders 0.87%		191,776
NRG Energy, Inc. (I)	7,048	191,776
Industrial Conglomerates 1.06%		232,975
McDermott International, Inc.	11,923	232,975
Industrial Gases 0.82%		180,371
Airgas, Inc.	4,046	180,371
Industrial Machinery 1.59%		349,653
Flowserve Corp.	4,329	349,653
Integrated Oil & Gas 0.84%		183,978
InterOil Corp. (I)	6,501	183,978
Internet Retail 1.38%		304,126
Expedia, Inc.	14,685	304,126
Internet Software & Services 3.65%		804,079
Baidu, Inc., SADR (I)	792	275,727
NetEase.com, Inc., ADR (L)	3,854	169,807
VistaPrint Ltd. (I)(L)	8,692	358,545
Investment Banking & Brokerage 3.21%		707,412
Greenhill & Co., Inc.	4,870	366,808
Lazard Ltd. (Class A)	9,208	340,604
Life & Health Insurance 1.46%		321,312
Prudential Financial, Inc.	7,258	321,312

Page 2 

John Hancock Mid Cap Equity Fund
Securities owned by the Fund on
July 31, 2009 (Unaudited)

	Shares	Value
Life Sciences Tools & Services 1.43%		313,636
QIAGEN NV (I)(L)	16,542	313,636
Metal & Glass Containers 1.12%		246,710
Owens-Illinois, Inc. (I)	7,269	246,710
Oil & Gas Equipment & Services 2.25%		495,991
Core Laboratories NV	1,775	152,579
Dresser-Rand Group, Inc.	6,719	195,590
IHS, Inc. (Class A) (I)	2,960	147,822
Oil & Gas Exploration & Production 3.27%		719,042
Cabot Oil & Gas Corp.	8,624	302,961
Denbury Resources, Inc. (I)	11,373	188,792
SandRidge Energy, Inc. (L)	24,309	227,289
Packaged Foods & Meats 1.65%		363,861
Dean Foods Co.	8,010	169,732
Hormel Foods Corp.	5,406	194,129
Personal Products 1.01%		221,434
Alberto-Culver Co.	8,643	221,434
Pharmaceuticals 2.28%		502,740
Mylan, Inc. (I)(L)	21,523	283,888
Shire PLC, ADR	4,884	218,852
Regional Banks 0.88%		192,744
Cullen/Frost Bankers, Inc.	4,013	192,744
Research & Consulting Services 3.74%		823,387
FTI Consulting, Inc. (I)	7,082	385,473
Stantec, Inc. (I)	17,302	437,914
Restaurants 1.27%		279,051
Chipotle Mexican Grill, Inc. (Class A) (I)(L)	2,974	279,051
Security & Alarm Services 1.42%		311,940
Corrections Corp. of America (I)	18,073	311,940
Semiconductor Equipment 0.82%		180,475
Novellus Systems, Inc.	9,222	180,475
Semiconductors 6.59%		1,450,007
Broadcom Corp. (Class A) (I)	16,177	456,677
Marvell Technology Group, Ltd.	13,416	178,969
ON Semiconductor Corp.	39,772	290,336
Silicon Laboratories, Inc. (I)	12,235	524,025
Soft Drinks 1.26%		276,485
Hansen Natural Corp. (I)	8,916	276,485
Specialty Chemicals 0.64%		140,306
Lubrizol Corp.	2,422	140,306
Specialty Stores 0.70%		155,091
PetSmart, Inc.	6,933	155,091

Page 3 

John Hancock Mid Cap Equity Fund
Securities owned by the Fund on
July 31, 2009 (Unaudited)

				Shares	Value
Steel 3.17%					698,491
Ak Steel Holding Corp.				10,523	206,987
Cliffs Natural Resources, Inc.				7,722	211,506
Schnitzer Steel Industries, Inc. (Class A)				2,019	108,562
Steel Dynamics, Inc.				10,479	171,436
Trucking 1.71%					375,281
J.B. Hunt Transport Services, Inc.				5,268	147,241
Landstar System, Inc.				6,217	228,040
Wireless Telecommunication Services 1.36%					299,958
American Tower Corp. (Class A) (I)				8,799	299,958
Short-term investments 14.66%					$3,226,638
(Cost $3,225,361)
			Rate	Shares	Value
Cash Equivalents 0.00%					2,426,642
John Hancock Collateral Investment Trust(T)(W)			0.4185% (Y)	242,400	2,426,642
		Maturity
	Rate	date		Par value	Value
U.S. Government Agency 3.63%					799,996
Federal Home Loan Bank,
Discount Note	0.090%	08/03/09		800,000	799,996
Total investments (Cost $23,895,539)† 112.08%					$24,663,835
Other assets and liabilities, net (12.08%)					($2,658,651)
Total net assets 100.00%					$22,005,184

The percentage shown for each investment category is the total value of the category as a percentage of the net assets of the Fund.

ADR American Depositary Receipts

SADR Sponsored American Depositary Receipts

(I) Non-income producing security.

(L) All or a portion of this security is on loan as of July 31, 2009.

(T) Represents investment of securities lending collateral.

(W) Issuer is an affiliate of John Hancock Advisers, LLC (the Adviser).

(Y) The rate shown is annualized seven-day yield as of July 31, 2009.

† At July 31, 2009, the aggregate cost of investment securities for federal income tax purposes was $24,029,283. Net unrealized appreciation aggregated $634,552, of which $2,346,056 related to appreciated investment securities and $1,711,504 related to depreciated investment securities.

Page 4 

Notes to the Schedule of Investments (Unaudited)

Security valuation
Security Valuation Investments are stated at value as of the close of the regular trading on the New York Stock Exchange (NYSE), normally at 4:00 P.M., Eastern Time. Equity securities held by the Fund are valued at the last sale price or official closing price (closing bid price or last evaluated price if no sale has occurred) as of the close of business on the principal securities exchange (domestic or foreign) on which they trade. Debt obligations are valued based on the evaluated prices provided by an independent pricing service, which utilizes both dealer-supplied and electronic data processing techniques, which take into account factors such as institutional-size trading in similar groups of securities, yield, quality, coupon rate, maturity, type of issue, trading characteristics and other market data. Foreign securities and currencies are valued in U.S. dollars, based on foreign currency exchange rates supplied by an independent quotation service. Securities traded only in the over-the-counter market are valued at the last bid price quoted by brokers making markets in the securities at the close of trading. Equity and debt obligations, for which there are no prices available from an independent pricing service, are value based on broker quotes or fair valued as described below. Certain short-term debt instruments are valued at amortized cost. John Hancock Collateral Investment Trust (JHCIT), an affiliated registered investment company managed by MFC Global Investment Management (U.S.), LLC, a subsidiary of Manulife Financial Corporation (MFC), is valued at its net asset value each business day. JHCIT is a floating rate fund investing in money market instruments.

Other portfolio securities and assets for which no such quotations are readily available are valued at fair value as determined in good faith by the Fund’s Pricing Committee in accordance with procedures adopted by the Board of Trustees. Generally, trading in non-U.S. securities is substantially completed each day at various times prior to the close of trading on the NYSE. The values of such securities used in computing the net asset value of the Fund’s shares are generally determined as of such times. Occasionally, significant events that affect the values of such securities may occur between the times at which such values are generally determined and the close of the NYSE. Upon such an occurrence, these securities will be valued at fair value as determined in good faith under consistently applied procedures established by and under the general supervision of the Board of Trustees.

Valuations change in response to many factors including the historical and prospective earnings of the issuer, the value of the issuer’s assets, general economic conditions and market conditions, interest rates, investor perceptions and market liquidity.

Fair Value Measurements

The Fund uses a three-tier hierarchy to prioritize the assumptions, referred to as inputs, used in valuation techniques to measure fair value. The three-tier hierarchy of inputs and the valuation techniques used are summarized below:

• Level 1 — Exchange traded prices in active markets for identical securities. This technique is used for exchange-traded domestic common and preferred equities, certain foreign equities, warrants, rights, options and futures. In addition, investment companies, including mutual funds, are valued using this technique.

• Level 2 — Prices determined using significant observable inputs. Observable inputs may include quoted prices for similar securities, interest rates, prepayment speeds and credit risk. Prices for securities valued using these techniques are received from independent pricing vendors and are based on an evaluation of the inputs described. These techniques are used for certain domestic preferred equities, certain foreign equities, unlisted rights and warrants, and fixed income securities. Also, over-the-counter derivative contracts, including swaps, foreign forward currency contracts, and certain options use these techniques.

5 

• Level 3 — Prices determined using significant unobservable inputs. In situations where quoted prices or observable inputs are unavailable, such as when there is little or no market activity for an investment, unobservable inputs may be used. Unobservable inputs reflect the Trust’s Pricing Committee’s own assumptions about the factors that market participants would use in pricing an investment and would be based on the best information available. Securities using this technique are generally thinly traded or privately placed, and may be valued using broker quotes, which may not only use observable or unobservable inputs but may also include the use of the brokers’ own judgments about the assumptions that market participants would use.

The inputs or methodology used for valuing securities are not necessarily an indication of the risk associated with investing in those securities.

The following is a summary of the inputs used to value the Funds’ investments as of July 31, 2009, by major security category or security type.

Investments in Securities		Level 1		Level 2	Level 3		Total
Consumer Discretionary	$	3,222,014		-	-	$	3,222,014
Consumer Staples		1,056,178		-	-		1,056,178
Energy		1,676,417		-	-		1,676,417
Financials		1,688,938		-	-		1,688,938
Health Care		3,544,113		-	-		3,544,113
Industrials		2,895,400		-	-		2,895,400
Information Technology		5,050,713		-	-		5,050,713
Materials		1,811,690		-	-		1,811,690
Telecommunication Services		299,958		-	-		299,958
Utilities		191,776		-	-		191,776
Short-term Investments		2,426,642	$	799,996	-		3,226,638
Total Investments in Securities	$	21,437,197	$	799,996	-	$	24,663,835

Securities lending
The Fund may lend portfolio securities from time to time in order to earn additional income. The Fund retains beneficial ownership of the securities it has loaned and continues to receive interest and dividends associated with securities and to participate in any changes in their value. On the settlement date of the loan, the Fund receives cash collateral against the loaned securities and maintains the cash collateral in an amount no less than the market value of the loaned securities.

The market value of the loaned securities is determined at the close of business of the Fund. Any additional required cash collateral is delivered to the Fund or excess collateral is returned to the borrower on the next business day. Cash collateral received is invested in JHCIT. JHCIT is not a stable value fund and thus the Fund receives the benefit of any gains and bears any losses generated by JHCIT.

The Fund may receive compensation for lending their securities either in the form of fees, and/or by retaining a portion of interest on the investment of any cash received as collateral. If the borrower defaults on its obligation to return the securities loaned because of insolvency or other reasons, the Fund could experience delays and costs in recovering the securities loaned or in gaining access to the collateral. The Fund bears the risk in the event that invested collateral is not sufficient to meet obligations due on loans.

6 

Risk and uncertainties

Sector risk
The Fund may focus its investments in a particular industry, sector of the economy or invest in a limited number of companies. The focus is closely tied to a single sector of the economy which may cause the Fund to underperform other sectors. Specifically, technology companies can be hurt by economic declines, regulatory, market and other factors. Accordingly, this may make the Fund’s value more volatile and investment values may rise and fall more rapidly than a fund that is less focused.

7 

ITEM 2. CONTROLS AND PROCEDURES.

(a) Based upon their evaluation of the registrant's disclosure controls and procedures as conducted within 90 days of the filing date of this Form N-Q, the registrant's principal executive officer and principal accounting officer have concluded that those disclosure controls and procedures provide reasonable assurance that the material information required to be disclosed by the registrant on this report is recorded, processed, summarized and reported within the time periods specified in the Securities and Exchange Commission's rules and forms.

(b) There were no changes in the registrant's internal control over financial reporting that occurred during the registrant's last fiscal quarter that has materially affected, or is reasonably likely to materially affect, the registrant's internal control over financial reporting.

ITEM 3. EXHIBITS.

Separate certifications for the registrant's principal executive officer and principal accounting officer, as required by Rule 30a-2(a) under the Investment Company Act of 1940, are attached.

SIGNATURES 

Pursuant to the requirements of the Securities Exchange Act of 1934 and the Investment Company Act of 1940, the registrant has duly caused this report to be signed on its behalf by the undersigned, thereunto duly authorized.

John Hancock Series Trust

By: /s/ Keith F. Hartstein
-------------------------------------
Keith F. Hartstein
President and Chief Executive Officer

Date: September 15, 2009

Pursuant to the requirements of the Securities Exchange Act of 1934 and the Investment Company Act of 1940, this report has been signed below by the following persons on behalf of the registrant and in the capacities and on the dates indicated.

By: /s/ Keith F. Hartstein
-------------------------------------
Keith F. Hartstein
President and Chief Executive Officer

Date: September 15, 2009

By: /s/ Charles A. Rizzo
-------------------------------------
Charles A. Rizzo
Chief Financial Officer

Date: September 15, 2009