ex23-1.htm

We consent to the incorporation by reference in Registration Statements Nos. 333-72201, 333-94071, 333-68846, 333-73894, 333-76756, 333-102284, 333-105066, 333-115283, 333-124868, 333-140785, 333-148692, 333-157388, 333-159241, 333-164010, 333-172308, 333-174328, 333-178795, and 333-182235, all on Form S-8 of ISC8, Inc.(the “Company”), of our report dated December 28, 2012, relating to our audit of the consolidated financial statements, which appears in this Annual Report on Form 10-K of ISC8, Inc. for the year ended September 30, 2012. Our report dated December 28, 2012 relating to the consolidated financial statements includes an emphasis paragraph relating to uncertainty as to the company’s ability to continue as a going concern.