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Related Party Transactions (Details)
1 Months Ended 3 Months Ended 9 Months Ended
Jan. 06, 2018
shares
Jul. 31, 2019
USD ($)
Dec. 31, 2017
USD ($)
shares
Sep. 30, 2019
USD ($)
agreement
Sep. 30, 2018
USD ($)
Jun. 30, 2017
USD ($)
Sep. 30, 2019
USD ($)
director
agreement
Sep. 30, 2018
USD ($)
Mar. 31, 2018
USD ($)
Dec. 31, 2018
USD ($)
Mar. 07, 2017
shares
Sep. 30, 2016
USD ($)
shares
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                        
Number of exclusive channel collaboration agreements (agreement) | agreement       2     2          
Related party payable       $ 72,000     $ 72,000     $ 100,000    
Research and development expense       763,000 $ 1,541,000   3,306,000 $ 4,601,000        
Common stock issued (shares) | shares 409,091                      
Warrants Issued With September 2016 Convertible Notes                        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                        
Warrants issued to purchase common stock (in shares) | shares                       1,205,840
Affiliated Entity                        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                        
Expenses for work performed             100,000 400,000        
Related party payable       100,000     100,000     $ 100,000    
Research and development expense       $ 4,000 63,000   $ 44,000 (134,000)        
Shareholder ownership percentage of related party in affiliate, more than       50.00%     50.00%          
Shareholder ownership percentage       17.00%     17.00%          
Affiliated Entity | 2017 Private Placement                        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                        
Warrants issued to purchase common stock (in shares) | shares     545,456               259,176  
Preferred stock, shares issued (shares) | shares                     3,016  
Common stock issued (shares) | shares     545,456                  
Affiliated Entity | Warrants Issued With September 2016 Convertible Notes                        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                        
Warrants issued to purchase common stock (in shares) | shares                       450,835
Affiliated Entity | Convertible Debt                        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                        
Convertible debt principal                       $ 6,762,500
Affiliated Entity | CCP Milestone Payment                        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                        
Royalty and milestone payments incurred   $ 3,800,000                    
Expenses for work performed             $ 3,800,000          
Related party payable       $ 3,800,000     3,800,000          
Affiliated Entity | Direct Expenses for Work Performed                        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                        
Expenses for work performed             10,000 100,000        
Affiliated Entity | Pass-through Costs                        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                        
Expenses for work performed             $ 90,000 300,000        
Affiliated Entity | 2012 ECC Dispute                        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                        
Related party payable     $ 700,000   $ 200,000     $ 200,000 $ 200,000      
Research and development expense           $ 1,100,000     1,400,000      
Due to related parties, reduction from prior period                 $ 500,000      
Director                        
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]                        
Number of directors (director) | director             2