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Revenue from Contracts with Customers (Details)
3 Months Ended 6 Months Ended
Apr. 12, 2019
USD ($)
day
Jun. 30, 2019
USD ($)
Jun. 30, 2018
USD ($)
Jun. 30, 2019
USD ($)
Jun. 30, 2018
USD ($)
Dec. 31, 2018
USD ($)
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]            
Revenues   $ 21,792,000 $ 0 $ 21,792,000 $ 0  
Contract with customer, asset   12,718,000   12,718,000   $ 0
Contract asset - long term   4,279,000   4,279,000    
Allowance for credit loss   0   0    
Revenue recognized, previously included in contract liability   0   0    
Castle Creek Pharmaceuticals, LLC Co-Development And License Agreement            
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]            
Contract with customer, asset   13,500,000   13,500,000    
Remaining performance obligation $ 10,700,000 9,900,000   9,900,000    
Castle Creek Pharmaceuticals, LLC Co-Development And License Agreement | Castle Creek Pharmaceuticals, LLC            
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]            
Maximum development costs payable by other party $ 20,000,000          
Excess costs payable by other party (percent) 70.00%          
Excess costs payable (percent) 30.00%          
Upfront payment received $ 7,500,000          
Value of development services 21,700,000          
First milestone payment receivable 2,500,000          
Total transaction price at inception 31,700,000          
Second milestone payment receivable 30,000,000          
Maximum sales milestone payments receivable 75,000,000          
First sales milestone payment receivable 25,000,000          
First product sales threshold for sales milestone payments 250,000,000          
Second sales milestone receivable 50,000,000          
Second product sales threshold for sales milestone payments $ 750,000,000          
Gross profit receivable from other party (percent of product sales) 30.00%          
Payments due to third party 50.00%          
Term of arrangement (years) 40 years          
Days written notice required to terminate (days) | day 180          
Gross profit owed in event of termination (percentage) 5.00%          
Initial transaction price $ 29,200,000          
Maximum payable period (days) 60          
Intellectual Property | Castle Creek Pharmaceuticals, LLC Co-Development And License Agreement | Castle Creek Pharmaceuticals, LLC            
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]            
Intangible asset $ 21,000,000          
Revenues   21,000,000   21,000,000    
License Services | Castle Creek Pharmaceuticals, LLC Co-Development And License Agreement | Castle Creek Pharmaceuticals, LLC            
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]            
Fair value (as a percent of overall value) 72.00%          
Research and development services            
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]            
Revenues   $ 813,000 $ 0 $ 813,000 $ 0  
Research and development services | Castle Creek Pharmaceuticals, LLC Co-Development And License Agreement | Castle Creek Pharmaceuticals, LLC            
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]            
Fair value (as a percent of overall value) 28.00%          
Intangible asset $ 8,200,000