Property and Equipment (Details) - USD ($) $ in Thousands	Dec. 31, 2016	Dec. 31, 2015
Total property and equipment, gross	$ 3,050	$ 2,824
Less: Accumulated depreciation	(1,561)	(1,242)
Total property and equipment, net	1,489	1,582
Laboratory equipment
Total property and equipment, gross	1,429	1,416
Computer equipment and software
Total property and equipment, gross	313	296
Furniture and fixtures
Total property and equipment, gross	44	53
Leasehold improvements
Total property and equipment, gross	1,228	903
Construction-in-process
Total property and equipment, gross	$ 36	$ 156