Inventory (Details) - USD ($)	12 Months Ended
	Dec. 31, 2016	Dec. 31, 2015
Inventory [Line Items]
Loss on write-down of inventory	$ 356,000	$ 0
Raw materials (LAVIV and product candidates)	0	338,000
Work-in-process (LAVIV)	0	144,000
Total inventory, net	0	$ 482,000
Cost of Sales
Inventory [Line Items]
Loss on write-down of inventory	$ 400,000