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Income Taxes - Reconciliation of Income Taxes/(Benefit) (Details) - USD ($)
$ in Thousands
12 Months Ended
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Effective Income Tax Rate Reconciliation, Amount [Abstract]      
Tax benefit at U.S. federal statutory rate $ (12,183) $ (8,977) $ (11,044)
Increase in domestic valuation allowance 14,236 11,109 11,626
State income taxes/(benefit) before valuation allowance, net of federal benefit (1,122) (846) (1,026)
Warrant revaluation and other finance (income)/expense (1,026) (1,375) 369
Other 95 89 75
Income tax expense (benefit) $ 0 $ 0 $ 0