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Equity (Details) - USD ($)
$ / shares in Units, $ in Thousands
3 Months Ended 12 Months Ended
Jul. 27, 2015
Oct. 01, 2013
Mar. 31, 2014
Sep. 30, 2013
Dec. 31, 2015
Dec. 31, 2014
Dec. 31, 2013
Oct. 31, 2012
Class of Stock [Line Items]                
Common stock, fair value       $ 6,400        
Common stock, fair value (shares)       1,243,781        
Common stock, closing price (usd per share)       $ 5.15        
Proceeds from public offering, gross $ 17,300              
Proceeds from public offering, net $ 15,900       $ 15,872 $ 0 $ 47,118  
Preferred stock authorized for issuance (shares)         5,000,000      
Preferred shares issued (in shares)         0 0    
Preferred shares outstanding (in shares)         0 0    
Common Stock                
Class of Stock [Line Items]                
Underwritten public offering (shares) 2,586,206              
Common stock issued (usd per share) $ 5.80              
Common Stock | Over-Allotment Option                
Class of Stock [Line Items]                
Underwritten public offering (shares) 387,930              
Offering                
Class of Stock [Line Items]                
Underwritten public offering (shares)   11,000,000            
Public offering (usd per share)   $ 4.10            
Additional common stock (shares)   1,311,698            
Affiliated Entity                
Class of Stock [Line Items]                
Common stock, fair value (shares)     1,024,590          
Common stock, closing price (usd per share)     $ 5.03          
Affiliated Entity | Research and Development Expense                
Class of Stock [Line Items]                
Common stock, fair value     $ 5,200          
Common Stock                
Class of Stock [Line Items]                
Subscription receivable               $ 2,000
Underwritten public offering (shares)         2,974,136   12,311,698  
Proceeds from public offering   $ 42,100            
Increase in proceeds from public offering   $ 47,100