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Stock-Based Compensation (Tables)
 12 Months Ended
Dec. 31, 2015
Disclosure of Compensation Related Costs, Share-based Payments [Abstract]  
Details of Fair Value Option Award
The fair market value of the stock options at the date of grant was estimated using the Black-Scholes option-pricing model with the following weighted average assumptions for the years ended December 31:
 
2015
 
2014
 
2013
Expected life (1)
6 years, 1 month

 
5 years, 11 months

 
5 years, 7 months

Interest rate
1.6
%
 
1.9
%
 
1.6
%
Dividend yield
—

 
—

 
—

Volatility (2)
103.2
%
 
70.0
%
 
71.0
%
(1)
The Company uses the simplified method for estimating the stock option term.
(2)
The Company uses historical volatility of a peer group for estimating expected volatility of the Company's shares.
Summary of Stock-Based Compensation Expense
Total stock-based compensation expense, net of estimated forfeitures, recognized using the straight-line attribution method in the Consolidated Statements of Operations for the years ended December 31, 2015, 2014 and 2013 was as follows:
($ in thousands)
2015
 
2014
 
2013
Research and development:
 
 
 
 
 
Stock-based compensation expense for employees
$
158

 
$
38

 
$
32

Equity awards for non-employees issued for services
—

 
3

 
4

Selling, general and administrative:
 
 
 
 
 
Stock-based compensation expense for employees and directors
1,880

 
1,198

 
1,013

Equity awards for non-employees issued for services
—

 
—

 
101

Total stock-based compensation expense
$
2,038

 
$
1,239

 
$
1,150
Summary of Stock Option Activity
($ in thousands, except share and per share data)
Number of shares
 
Weighted-
average 
exercise 
price
 
Weighted-
average
 remaining 
contractual term
 (in years)
 
Aggregate 
intrinsic 
value
Outstanding at December 31, 2012
562,025

 
$
18.56

 
7 years
 
$
—

Granted
1,532,000

 
4.15

 
 
 
 

Forfeited
(25,305
)
 
14.71

 
 
 
 

Outstanding at December 31, 2013
2,068,720

 
$
7.93

 
8 years, 5 months
 
$
544

Granted
348,000

 
4.19

 
 
 
 

Expired
(51,637
)
 
21.61

 
 
 
 
Forfeited
(278,633
)
 
4.45

 
 
 
 

Outstanding at December 31, 2014
2,086,450

 
$
7.43

 
7 years, 2 months
 
$
—

Granted
1,352,114

 
4.48

 
 
 
 

Exercised
(56,250
)
 
4.53

 
 
 
 
Expired
(65,250
)
 
10.54

 
 
 
 
Forfeited
(182,970
)
 
5.91

 
 
 
 

Outstanding at December 31, 2015
3,134,094

 
$
6.23

 
8 years
 
$
1,630

Vested and expected to vest at December 31, 2015
3,015,584

 
$
6.32

 
7 years, 11 months
 
$
1,556

Exercisable at December 31, 2015
1,479,939

 
$
8.47

 
7 years, 1 month
 
$
624