<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0201</schemaVersion>

    <documentType>3</documentType>

    <periodOfReport>2004-02-10</periodOfReport>

    <noSecuritiesOwned>0</noSecuritiesOwned>

    <issuer>
        <issuerCik>0000356591</issuerCik>
        <issuerName>NEUROLOGIX INC/DE</issuerName>
        <issuerTradingSymbol>NLGX</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001279231</rptOwnerCik>
            <rptOwnerName>PALISADE PRIVATE PARTNERSHIP L P</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>ONE BRIDGE PLAZA</rptOwnerStreet1>
            <rptOwnerStreet2>SUITE 695</rptOwnerStreet2>
            <rptOwnerCity>FORT LEE</rptOwnerCity>
            <rptOwnerState>NJ</rptOwnerState>
            <rptOwnerZipCode>07024</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>0</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>1</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeHolding>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>170047256</value>
                    <footnoteId id="F1"/>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeHolding>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">Mark Hoffman, a director and officer of Neurologix, Inc. is a  managing member of Palisade Private Holdings, LLC, the general partner of Palisade Private Partnership L.P. Mr. Hoffman and the other managing members of Palisade Private Holdings, LLC disclaim beneficial ownership of the shares held by Palisade Private Partnership, L.P., except to the extent of their percuniary interest in the shares and this report shall not be deemed an admission that the
managing members are the beneficial owners of the shares for purposes of Section 16 or for any other purpose.</footnote>
    </footnotes>

    <remarks>See Attached Exhibit 99 - Joint Filer Information</remarks>

    <ownerSignature>
        <signatureName>/s/ Mark Hoffman</signatureName>
        <signatureDate>2004-02-19</signatureDate>
    </ownerSignature>
</ownershipDocument>

