September 18, 2013

VIA EDGAR

U.S. Securities and Exchange Commission

100 F Street, N.E.

Washington, D.C. 20549

RE: Great-West Funds, Inc.

Submission Pursuant to Rule 497 under the Securities Act of 1933

File Nos. 2-75503, 811-03364

Commissioners:

Electronically submitted herewith is a filing made pursuant to Rule 497 under the Securities Act of 1933 for Great-West Funds, Inc.

This submission, filed pursuant to Rule 497 under the Securities Act of 1933, is for the purpose of submitting exhibits containing interactive data format risk/return summary information for the Great-West Multi-Manager Large Cap Growth Fund that mirrors the risk/return summary information contained in the submission filed pursuant to Rule 497 on September 3, 2013.

Please direct any question or comment regarding the foregoing to me at (303) 737-4675 or to Renee Hardt at Vedder Price P.C. at (312) 609-7616.

Very truly yours,

/s/ Ryan L. Logsdon

Ryan L. Logsdon

Assistant Vice President, Counsel & Secretary

Enclosures

GREAT-WEST FUNDS, INC.

The principal underwriter of Great-West Funds, Inc. is GWFS Equities, Inc., an affiliate of Great-West Funds, Inc.

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