X0101 EFFECT 33 LIVE 2017-06-12 0000891092-17-004385 485APOS 0000355916 BlackRock Variable Series Funds, Inc. 002-74452 S000002876 BlackRock Large Cap Core V.I. Fund C000007905 Class I S000002876 BlackRock Large Cap Core V.I. Fund C000007906 Class II S000002876 BlackRock Large Cap Core V.I. Fund C000007907 Class III S000002877 BlackRock Large Cap Growth V.I. Fund C000007908 Class I S000002877 BlackRock Large Cap Growth V.I. Fund C000007910 Class III S000002878 BlackRock Large Cap Value V.I. Fund C000007911 Class I S000002878 BlackRock Large Cap Value V.I. Fund C000007912 Class II S000002878 BlackRock Large Cap Value V.I. Fund C000007913 Class III S000002879 BlackRock Value Opportunities V.I. Fund C000007914 Class I S000002879 BlackRock Value Opportunities V.I. Fund C000007915 Class II S000002879 BlackRock Value Opportunities V.I. Fund C000007916 Class III