<?xml version="1.0" encoding="utf-8"?>
<ownershipDocument>
    <schemaVersion>X0201</schemaVersion>

    <documentType>4</documentType>
  <periodOfReport>2003-11-04</periodOfReport>
  <notSubjectToSection16>0</notSubjectToSection16>
    <issuer>
        <issuerCik>0000353569</issuerCik>
        <issuerName>QUIDEL CORP /DE/</issuerName>
        <issuerTradingSymbol>QDEL</issuerTradingSymbol>
  </issuer>
  <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001187716</rptOwnerCik>
            <rptOwnerName>POLAN MARY LAKE PH D</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>4251 MANUELA AVENUE</rptOwnerStreet1>
            <rptOwnerStreet2></rptOwnerStreet2>
            <rptOwnerCity>PALO ALTO</rptOwnerCity>
            <rptOwnerState>CA</rptOwnerState>
            <rptOwnerZipCode>94306</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
            <reportingOwnerRelationship>
      <isDirector>1</isDirector>
      <isOfficer>0</isOfficer>
      <isTenPercentOwner>0</isTenPercentOwner>
      <isOther>0</isOther>
    </reportingOwnerRelationship>
  </reportingOwner>
  <nonDerivativeTable>
    <nonDerivativeTransaction>
      <securityTitle>
        <value>Common Stock</value>
      </securityTitle>
      <transactionDate>
        <value>2003-11-04</value>
      </transactionDate>
      <transactionCoding>
        <transactionFormType>4</transactionFormType>
        <transactionCode>M</transactionCode>
        <equitySwapInvolved>0</equitySwapInvolved>
      </transactionCoding>
      <transactionTimeliness>
        <value></value>
      </transactionTimeliness>
      <transactionAmounts>
        <transactionShares>
          <value>12500</value>
        </transactionShares>
        <transactionPricePerShare>
          <value>3.625</value>
        </transactionPricePerShare>
        <transactionAcquiredDisposedCode>
          <value>A</value>
        </transactionAcquiredDisposedCode>
      </transactionAmounts>
      <postTransactionAmounts>
        <sharesOwnedFollowingTransaction>
          <value>30500</value>
          <footnoteId id="F1"/>
        </sharesOwnedFollowingTransaction>
      </postTransactionAmounts>
      <ownershipNature>
        <directOrIndirectOwnership>
          <value>D</value>
        </directOrIndirectOwnership>
      </ownershipNature>
    </nonDerivativeTransaction>
    <nonDerivativeTransaction>
      <securityTitle>
        <value>Common Stock</value>
      </securityTitle>
      <transactionDate>
        <value>2003-11-04</value>
      </transactionDate>
      <transactionCoding>
        <transactionFormType>4</transactionFormType>
        <transactionCode>S</transactionCode>
        <equitySwapInvolved>0</equitySwapInvolved>
      </transactionCoding>
      <transactionTimeliness>
        <value></value>
      </transactionTimeliness>
      <transactionAmounts>
        <transactionShares>
          <value>12500</value>
        </transactionShares>
        <transactionPricePerShare>
          <value>8.00</value>
        </transactionPricePerShare>
        <transactionAcquiredDisposedCode>
          <value>D</value>
        </transactionAcquiredDisposedCode>
      </transactionAmounts>
      <postTransactionAmounts>
        <sharesOwnedFollowingTransaction>
          <value>18000</value>
          <footnoteId id="F1"/>
        </sharesOwnedFollowingTransaction>
      </postTransactionAmounts>
      <ownershipNature>
        <directOrIndirectOwnership>
          <value>D</value>
        </directOrIndirectOwnership>
      </ownershipNature>
    </nonDerivativeTransaction>
  </nonDerivativeTable>
  <derivativeTable>
    <derivativeTransaction>
      <securityTitle>
        <value>Non-Qualified Stock Option</value>
      </securityTitle>
      <conversionOrExercisePrice>
        <value>3.625</value>
      </conversionOrExercisePrice>
      <transactionDate>
        <value>2003-11-04</value>
      </transactionDate>
      <transactionCoding>
        <transactionFormType>4</transactionFormType>
        <transactionCode>M</transactionCode>
        <equitySwapInvolved>0</equitySwapInvolved>
      </transactionCoding>
      <transactionTimeliness>
        <value></value>
      </transactionTimeliness>
      <transactionAmounts>
        <transactionShares>
          <value>12500</value>
        </transactionShares>
        <transactionPricePerShare>
          <value>0.00</value>
        </transactionPricePerShare>
        <transactionAcquiredDisposedCode>
          <value>D</value>
        </transactionAcquiredDisposedCode>
      </transactionAmounts>
      <exerciseDate>
        <value>1998-07-30</value>
      </exerciseDate>
      <expirationDate>
        <value>2006-07-30</value>
      </expirationDate>
      <underlyingSecurity>
        <underlyingSecurityTitle>
          <value>Common Stock</value>
        </underlyingSecurityTitle>
        <underlyingSecurityShares>
          <value>12500</value>
        </underlyingSecurityShares>
      </underlyingSecurity>
      <postTransactionAmounts>
        <sharesOwnedFollowingTransaction>
          <value>27500</value>
        </sharesOwnedFollowingTransaction>
      </postTransactionAmounts>
      <ownershipNature>
        <directOrIndirectOwnership>
          <value>D</value>
        </directOrIndirectOwnership>
      </ownershipNature>
    </derivativeTransaction>
  </derivativeTable>
  <footnotes>
    <footnote id="F1">The Reporting Person also indirectly holds 3,000 shares of common stock held in trusts to benefit her children.  The Reporting Person has no authority to vote or dispose of these 3,000 shares and disclaims beneficial ownership of these 3,000 shares, except to the extent of her pecuniary interest, if any.</footnote>
  </footnotes>
  <ownerSignature>
    <signatureName>/s/ Paul E. Landers, Attorney-in-Fact for Mary Lake Polan</signatureName>
    <signatureDate>2003-11-05</signatureDate>
  </ownerSignature>
</ownershipDocument>

