Exhibit 23.1

CONSENT OF INDEPENDENT REGISTERED PUBLIC ACCOUNTING FIRM

We consent to the incorporation by reference in the following Registration Statements:

(1) Registration Statements (Form S-3 Nos. 333-59390, 333-44218 and 333-00667) of Quidel Corporation,

(2) Registration Statements (Form S-8 Nos. 333-224987, 333-212731, 333-197701, 333-182028, 333-166845, 333-166450, 333-144383, 333-127519, 333-116971, 333-67444, 333-10503 and 033-62577) pertaining to the 2018 Equity Incentive Plan, 2016 Equity Incentive Plan, Amended and Restated 1983 Employee Stock Purchase Plan, 1983 Employee Stock Purchase Plan, 2001 Equity Incentive Plan, 2010 Equity Incentive Plan and Amended and Restated 2010 Equity Incentive Plan, and

(3) Registration Statement (Form S-4 No. 333-262434) of Coronado Topco, Inc.;

of our reports dated February 17, 2022, with respect to the consolidated financial statements and schedule of Quidel Corporation and the effectiveness of internal control over financial reporting of Quidel Corporation included in this Annual Report (Form 10-K) of Quidel Corporation for the year ended December 31, 2021.

/s/ Ernst & Young LLP

San Diego, California

February 17, 2022