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No definition available.

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- Definition

Milestone payments made under agreement.

+ References

No definition available.

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- Definition

Royalty and license expense.

+ References

No definition available.

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- Definition

Amount of increase (decrease) in the value of a contingent consideration liability, including, but not limited to, differences arising upon settlement.

+ References

Reference 1: http://www.xbrl.org/2003/role/presentationRef
-Publisher FASB
-Name Accounting Standards Codification
-Topic 805
-SubTopic 30
-Section 50
-Paragraph 4
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-URI http://asc.fasb.org/extlink&oid=35744584&loc=d3e7008-128479

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- Definition

Amount of liability recognized arising from contingent consideration in a business combination.

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- Definition

Amount of liability recognized arising from contingent consideration in a business combination, expected to be settled within one year or the normal operating cycle, if longer.

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- Definition

Amount of liability recognized arising from contingent consideration in a business combination, expected to be settled beyond one year or the normal operating cycle, if longer.

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- Definition

Amount of contractual obligation, including but not limited to, long-term debt, capital lease obligations, operating lease obligations, purchase obligations, and other commitments.

+ References

No definition available.

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Amount of liabilities classified as other, due within one year or the normal operating cycle, if longer.

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Reference 1: http://www.xbrl.org/2003/role/presentationRef
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- Definition

The amount of cash paid for royalties during the current period.

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- Definition

Line items represent financial concepts included in a table. These concepts are used to disclose reportable information associated with domain members defined in one or many axes to the table.

+ References

No definition available.

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Commitments and Contingencies - Additional Information (Detail) € in Millions	3 Months Ended		9 Months Ended
	Sep. 30, 2016 USD ($)	Sep. 30, 2015 USD ($)	Sep. 30, 2016 USD ($)	Sep. 30, 2015 USD ($)	Sep. 30, 2016 EUR (€)	Dec. 31, 2015 USD ($)	Aug. 31, 2013 USD ($)	Aug. 31, 2013 EUR (€)	May 31, 2013 USD ($)
Sale Leaseback Transaction [Line Items]
Accrued in other current liabilities	$ 4,891,000		$ 4,891,000			$ 6,999,000
Company had royalty and license expenses relating to those agreements	100,000		600,000	$ 500,000
Current portion of contingent consideration	630,000		630,000			1,286,000
Contingent consideration non-current portion	4,445,000		4,445,000			4,230,000
Change in fair value of acquisition contingencies			353,000
Change in fair value of acquisition contingencies	600,000	$ 0	600,000.0	0
Research and development milestones [Member]
Sale Leaseback Transaction [Line Items]
Milestone payments paid	0	300,000	900,000	1,200,000
BioHelix [Member]
Sale Leaseback Transaction [Line Items]
Payments for royalties	0	$ 0	200,000	$ 100,000
Current portion of contingent consideration	600,000		600,000
Contingent consideration non-current portion	4,100,000		4,100,000
BioHelix [Member] \| Minimum [Member]
Sale Leaseback Transaction [Line Items]
Contingent consideration									$ 5,000,000
BioHelix [Member] \| Maximum [Member]
Sale Leaseback Transaction [Line Items]
Contingent consideration									$ 10,000,000
Andiatec Acquisition [Member]
Sale Leaseback Transaction [Line Items]
Contingent consideration non-current portion	100,000		100,000
Andiatec Acquisition [Member] \| Research and development milestones [Member]
Sale Leaseback Transaction [Line Items]
Contingent consideration	3,400,000		3,400,000		€ 3.0
Andiatec Acquisition [Member] \| Maximum [Member]
Sale Leaseback Transaction [Line Items]
Contingent consideration							$ 600,000	€ 0.5
Claims and litigation [Member]
Sale Leaseback Transaction [Line Items]
Accrued in other current liabilities	0		0			200,000
Research and Development Agreements [Member]
Sale Leaseback Transaction [Line Items]
Current commitments	$ 2,800,000		$ 2,800,000			$ 4,200,000