Consolidated Balance Sheets - USD ($) $ in Thousands	Dec. 31, 2015	Dec. 31, 2014
Current assets:
Cash and cash equivalents	$ 191,471	$ 200,895
Accounts receivable, net	18,398	34,466
Inventories	26,388	24,763
Deferred tax asset—current	0	8,316
Restricted cash	63	3,127
Prepaid expenses and other current assets	4,344	2,914
Total current assets	240,664	274,481
Property, plant and equipment, net	52,547	49,226
Goodwill	80,730	80,748
Intangible assets, net	31,833	41,890
Other non-current assets	731	1,066
Total assets	406,505	447,411
Current liabilities:
Accounts payable	8,675	12,421
Accrued payroll and related expenses	9,627	8,349
Current portion of lease obligation	585	509
Current portion of contingent consideration	1,286	733
Deferred grant revenue	3,658	6,330
Other current liabilities	6,999	8,043
Total current liabilities	30,830	36,385
Long-term debt	143,297	137,958
Lease obligation, net of current portion	4,032	4,617
Contingent consideration—non-current	4,230	5,023
Deferred tax liability—non-current	1,970	14,890
Income taxes payable	910	806
Deferred rent	2,296	2,228
Other non-current liabilities	$ 264	$ 493
Commitments and contingencies (Note 6)
Stockholders’ equity:
Preferred stock, $.001 par value per share; 5,000 shares authorized; none issued or outstanding at December 31, 2015 and 2014	$ 0	$ 0
Common stock, $.001 par value per share; 97,500 shares authorized; 33,323 and 34,433 shares issued and outstanding at December 31, 2015 and 2014, respectively	33	34
Additional paid-in capital	209,121	229,374
Accumulated other comprehensive loss	(31)	(29)
Retained earnings	9,553	15,632
Total stockholders’ equity	218,676	245,011
Total liabilities and stockholders’ equity	$ 406,505	$ 447,411