Commitments and Contingencies - Additional Information (Detail) € in Millions	1 Months Ended	3 Months Ended		9 Months Ended
	Oct. 30, 2015 USD ($)	Sep. 30, 2015 USD ($)	Sep. 30, 2014 USD ($)	Sep. 30, 2015 USD ($)	Sep. 30, 2014 USD ($)	Sep. 30, 2015 EUR (€)	Dec. 31, 2014 USD ($)	Aug. 31, 2013 USD ($)	Aug. 31, 2013 EUR (€)	May. 31, 2013 USD ($)
Sale Leaseback Transaction [Line Items]
Accrued in other current liabilities		$ 9,238,000		$ 9,238,000			$ 8,043,000
Company had royalty and license expenses relating to those agreements		100,000	$ 0	500,000	$ 600,000
Current portion of contingent consideration		598,000		598,000			733,000
Contingent consideration non-current portion		5,009,000		5,009,000			5,023,000
Research and development milestones [Member]
Sale Leaseback Transaction [Line Items]
Milestone payments paid		300,000	600,000	1,200,000	900,000
BioHelix [Member]
Sale Leaseback Transaction [Line Items]
Payments for Royalties		0	$ 0	100,000	$ 49,000
Current portion of contingent consideration		600,000		600,000
Contingent consideration non-current portion		4,900,000		4,900,000
BioHelix [Member] | Minimum [Member]
Sale Leaseback Transaction [Line Items]
Contingent consideration										$ 5,000,000
BioHelix [Member] | Maximum [Member]
Sale Leaseback Transaction [Line Items]
Contingent consideration										$ 13,000,000
Andiatec Acquisition [Member]
Sale Leaseback Transaction [Line Items]
Current portion of contingent consideration		25,000		25,000
Contingent consideration non-current portion		100,000		100,000
Andiatec Acquisition [Member] | Research and development milestones [Member]
Sale Leaseback Transaction [Line Items]
Contingent consideration		3,400,000		3,400,000		€ 3.0
Andiatec Acquisition [Member] | Maximum [Member]
Sale Leaseback Transaction [Line Items]
Contingent consideration								$ 600,000	€ 0.5
Claims and litigation [Member]
Sale Leaseback Transaction [Line Items]
Accrued in other current liabilities		300,000		300,000			300,000
Research and Development Agreements [Member]
Sale Leaseback Transaction [Line Items]
Current commitments		$ 3,800,000		$ 3,800,000			$ 4,300,000
Subsequent Event [Member] | Research and development milestones [Member]
Sale Leaseback Transaction [Line Items]
Milestone payments paid	$ 500,000