Commitments and Contingencies - Additional Information (Detail) € in Millions	3 Months Ended		6 Months Ended
	Jun. 30, 2015 USD ($)	Jun. 30, 2014 USD ($)	Jun. 30, 2015 USD ($)	Jun. 30, 2014 USD ($)	Jun. 30, 2015 EUR (€)	Dec. 31, 2014 USD ($)	Aug. 31, 2013 USD ($)	Aug. 31, 2013 EUR (€)	May. 31, 2013 USD ($)
Sale Leaseback Transaction [Line Items]
Accrued in other current liabilities	$ 10,070,000		$ 10,070,000			$ 8,043,000
Company had royalty and license expenses relating to those agreements	200,000	$ 0	400,000	$ 500,000
Payment of contingent consideration			129,000	1,109,000
Current portion of contingent consideration	599,000		599,000			733,000
Contingent consideration non-current portion	5,009,000		5,009,000			5,023,000
Research and development milestones [Member]
Sale Leaseback Transaction [Line Items]
Milestone payments paid	500,000	$ 0	900,000	300,000
BioHelix [Member]
Sale Leaseback Transaction [Line Items]
Payments for Royalties	0		100,000	$ 49,000
Current portion of contingent consideration	600,000		600,000
Contingent consideration non-current portion	4,900,000		4,900,000
BioHelix [Member] | Minimum [Member]
Sale Leaseback Transaction [Line Items]
Contingent consideration									$ 5,000,000
BioHelix [Member] | Maximum [Member]
Sale Leaseback Transaction [Line Items]
Contingent consideration									$ 13,000,000
Andiatec Acquisition [Member]
Sale Leaseback Transaction [Line Items]
Current portion of contingent consideration	25,000		25,000
Contingent consideration non-current portion	100,000		100,000
Andiatec Acquisition [Member] | Research and development milestones [Member]
Sale Leaseback Transaction [Line Items]
Contingent consideration	3,400,000		3,400,000		€ 3.0
Andiatec Acquisition [Member] | Maximum [Member]
Sale Leaseback Transaction [Line Items]
Contingent consideration							$ 600,000	€ 0.5
Claims and litigation [Member]
Sale Leaseback Transaction [Line Items]
Accrued in other current liabilities	300,000		300,000			300,000
Research and Development Agreements [Member]
Sale Leaseback Transaction [Line Items]
Current commitments	$ 2,400,000		$ 2,400,000			$ 4,300,000