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Stock-Based Compensation - Schedule of Stock Option Activity (Details) - $ / shares
12 Months Ended
Dec. 31, 2019
Dec. 31, 2018
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding [Roll Forward]    
Number of options outstanding (in shares), ending 2,334,731  
Employee Stock Option    
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding [Roll Forward]    
Number of options outstanding (in shares), beginning 4,352,391 4,299,810
Number of options granted (in shares) 2,468,129 839,785
Number of options exercised (in shares) 0 (239,000)
Number of options expired (in shares) (761,780) 0
Number of options forfeited (in shares) (891,001) (548,204)
Number of options outstanding (in shares), ending 5,167,739 4,352,391
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract]    
Shares issuable under options exercise price per share (in dollars per share) $ 4.61 $ 5.09
Granted, exercise price per share (in dollars per share) 0.61 3.34
Exercised, exercise price per share (in dollars per share) 0 1.05
Expired, exercise price per share (in dollars per share) 2,420 0
Forfeited, exercise price per share (in dollars per share) 1.04 8.04
Shares issuable under options exercise price per share (in dollars per share) 3.34 4.61
Employee Stock Option | Minimum    
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract]    
Shares issuable under options exercise price per share (in dollars per share) 0.79 0.79
Granted, exercise price per share (in dollars per share) 0.55 1.73
Exercised, exercise price per share (in dollars per share)   1.02
Expired, exercise price per share (in dollars per share) 1.02  
Forfeited, exercise price per share (in dollars per share) 0.66 2.02
Shares issuable under options exercise price per share (in dollars per share) 0.55 0.79
Employee Stock Option | Maximum    
Share-based Compensation Arrangement by Share-based Payment Award, Options, Outstanding, Weighted Average Exercise Price [Abstract]    
Shares issuable under options exercise price per share (in dollars per share) 10.67 10.67
Granted, exercise price per share (in dollars per share) 1.80 4.25
Exercised, exercise price per share (in dollars per share)   1.83
Expired, exercise price per share (in dollars per share) 10.67  
Forfeited, exercise price per share (in dollars per share) 8.67 10.67
Shares issuable under options exercise price per share (in dollars per share) $ 10.67 $ 10.67