Accrued Expenses (Details) - USD ($) $ in Thousands	Dec. 31, 2017	Dec. 31, 2016
Payables and Accruals [Abstract]
Wholesaler fees	$ 7,044	$ 3,505
Capital expenditures	1,947	2,475
Payroll	1,580	1,706
Royalties	856	843
Studies	596	153
Professional fees	546	715
Interest expense	240	240
Income Tax	58	192
Other	635	520
Accrued Liabilities	$ 13,502	$ 10,349