Note 13 - Stock-Based Compensation (Detail) (USD $)	3 Months Ended
	Mar. 31, 2013	Mar. 31, 2012
Share-based Compensation	$ 266,387	$ 381,571
Employee Service Share-based Compensation, Nonvested Awards, Total Compensation Cost Not yet Recognized	494,000
Employee Service Share-based Compensation, Nonvested Awards, Total Compensation Cost Not yet Recognized, Period for Recognition	6 months
Employee and Office Grants (Member)
Employee Service share-based compensation, Forfeiture rate	15.00%
Employee Service share-based compensation, Forfeiture rate	15.00%
Director Grants (Member)
Employee Service share-based compensation, Forfeiture rate	0.00%
Employee Service share-based compensation, Forfeiture rate	0.00%
Employees and Directors [Member] | General and Administrative Expense [Member]
Share-based Compensation	160,000	245,000
Employees and Directors [Member]
Share-based Compensation	213,000	311,000
Research and Development Expense [Member]
Share-based Compensation	$ 53,000	$ 66,000