Note 5 - Novartis Agreement (Detail) (USD $)	3 Months Ended		6 Months Ended		99 Months Ended		6 Months Ended
	Jun. 30, 2012	Jun. 30, 2011	Jun. 30, 2012	Jun. 30, 2011	Jun. 30, 2012 Novartis [Member] Maximum [Member] License Agreement Terms [Member]	Jun. 30, 2012 Novartis [Member] License Agreement Terms [Member]	Jun. 30, 2012 Novartis [Member]
Research and Development Arrangement, Contract to Perform for Others, Compensation Earned					$ 18,700,000	$ 13,700,000
Licensing Agreement Milestone Payments Remaining						5,000,000
Licenses Revenue	$ 262,689	$ 705,162	$ 525,378	$ 1,267,851			$ 446,000