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Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
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MIC-Info: RSA-MD5,RSA,
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<SEC-DOCUMENT>0001437749-10-001898.txt : 20100621
<SEC-HEADER>0001437749-10-001898.hdr.sgml : 20100621
<ACCEPTANCE-DATETIME>20100621072111
ACCESSION NUMBER:		0001437749-10-001898
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20100618
FILED AS OF DATE:		20100621
DATE AS OF CHANGE:		20100621

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			Palmer Ashleigh
		CENTRAL INDEX KEY:			0001493714

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-16005
		FILM NUMBER:		10907080

	MAIL ADDRESS:	
		STREET 1:		81 FULTON ST.
		CITY:			BOONTON
		STATE:			NJ
		ZIP:			07005

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			UNIGENE LABORATORIES INC
		CENTRAL INDEX KEY:			0000352747
		STANDARD INDUSTRIAL CLASSIFICATION:	MEDICINAL CHEMICALS & BOTANICAL PRODUCTS [2833]
		IRS NUMBER:				222328609
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		81 FULTON STREET
		CITY:			BOONTON
		STATE:			NJ
		ZIP:			07005
		BUSINESS PHONE:		973-265-1100

	MAIL ADDRESS:	
		STREET 1:		81 FULTON STREET
		CITY:			BOONTON
		STATE:			NJ
		ZIP:			07005
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>rdgdoc.xml
<DESCRIPTION>PRIMARY DOCUMENT
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0303</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2010-06-18</periodOfReport>

    <issuer>
        <issuerCik>0000352747</issuerCik>
        <issuerName>UNIGENE LABORATORIES INC</issuerName>
        <issuerTradingSymbol>UGNE</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001493714</rptOwnerCik>
            <rptOwnerName>Palmer Ashleigh</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O UNIGENE LABORATORIES, INC</rptOwnerStreet1>
            <rptOwnerStreet2>81 FULTON STREET</rptOwnerStreet2>
            <rptOwnerCity>BOONTON</rptOwnerCity>
            <rptOwnerState>NJ</rptOwnerState>
            <rptOwnerZipCode>07005</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>1</isOfficer>
            <officerTitle>President &amp; CEO</officerTitle>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2010-06-18</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>P</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>2500.0000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0.7700</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>2500.0000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2010-06-18</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>4</transactionFormType>
                <transactionCode>P</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>18700.0000</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0.8000</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>21200.0000</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <ownerSignature>
        <signatureName>/s/ Ashleigh Palmer</signatureName>
        <signatureDate>2010-06-18</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----