-----BEGIN PRIVACY-ENHANCED MESSAGE-----
Proc-Type: 2001,MIC-CLEAR
Originator-Name: webmaster@www.sec.gov
Originator-Key-Asymmetric:
 MFgwCgYEVQgBAQICAf8DSgAwRwJAW2sNKK9AVtBzYZmr6aGjlWyK3XmZv3dTINen
 TWSM7vrzLADbmYQaionwg5sDW3P6oaM5D3tdezXMm7z1T+B+twIDAQAB
MIC-Info: RSA-MD5,RSA,
 VKRk9Iw6IPDz9Pd3nE1Zj4Tk5RmLX8vuVenRWYveCciApK4kv9KAg/fUB+ZxFGvt
 clI+Uacy3HF6RAHKczsNcw==

<SEC-DOCUMENT>0001181431-09-002023.txt : 20090108
<SEC-HEADER>0001181431-09-002023.hdr.sgml : 20090108
<ACCEPTANCE-DATETIME>20090108155931
ACCESSION NUMBER:		0001181431-09-002023
CONFORMED SUBMISSION TYPE:	4
PUBLIC DOCUMENT COUNT:		1
CONFORMED PERIOD OF REPORT:	20090106
FILED AS OF DATE:		20090108
DATE AS OF CHANGE:		20090108

ISSUER:		

	COMPANY DATA:	
		COMPANY CONFORMED NAME:			UNIGENE LABORATORIES INC
		CENTRAL INDEX KEY:			0000352747
		STANDARD INDUSTRIAL CLASSIFICATION:	MEDICINAL CHEMICALS & BOTANICAL PRODUCTS [2833]
		IRS NUMBER:				222328609
		STATE OF INCORPORATION:			DE
		FISCAL YEAR END:			1231

	BUSINESS ADDRESS:	
		STREET 1:		110 LITTLE FALLS RD
		CITY:			FAIRFIELD
		STATE:			NJ
		ZIP:			07004-2193
		BUSINESS PHONE:		9738820860

	MAIL ADDRESS:	
		STREET 1:		110 LITTLE FALLS RD
		CITY:			FAIRFIELD
		STATE:			NJ
		ZIP:			07004-2193

REPORTING-OWNER:	

	OWNER DATA:	
		COMPANY CONFORMED NAME:			MILLER MARVIN
		CENTRAL INDEX KEY:			0001239737

	FILING VALUES:
		FORM TYPE:		4
		SEC ACT:		1934 Act
		SEC FILE NUMBER:	000-16005
		FILM NUMBER:		09515845

	BUSINESS ADDRESS:	
		STREET 1:		C/O GTC BIOTHERAPEUTICS, INC.
		STREET 2:		175 CROSSING BOULEVARD
		CITY:			FRAMINGHAM
		STATE:			MA
		ZIP:			01702
		BUSINESS PHONE:		5086209700

	MAIL ADDRESS:	
		STREET 1:		GTC BIOTHERAPEUTICS, INC.
		STREET 2:		175 CROSSING BOULEVARD
		CITY:			FRAMINGHAM
		STATE:			MA
		ZIP:			01702
</SEC-HEADER>
<DOCUMENT>
<TYPE>4
<SEQUENCE>1
<FILENAME>rrd228336.xml
<TEXT>
<XML>
<?xml version="1.0"?>
<ownershipDocument>

    <schemaVersion>X0303</schemaVersion>

    <documentType>4</documentType>

    <periodOfReport>2009-01-06</periodOfReport>

    <notSubjectToSection16>0</notSubjectToSection16>

    <issuer>
        <issuerCik>0000352747</issuerCik>
        <issuerName>UNIGENE LABORATORIES INC</issuerName>
        <issuerTradingSymbol>UGNE</issuerTradingSymbol>
    </issuer>

    <reportingOwner>
        <reportingOwnerId>
            <rptOwnerCik>0001239737</rptOwnerCik>
            <rptOwnerName>MILLER MARVIN</rptOwnerName>
        </reportingOwnerId>
        <reportingOwnerAddress>
            <rptOwnerStreet1>C/O UNIGENE LABORATORIES, INC.</rptOwnerStreet1>
            <rptOwnerStreet2>81 FULTON STREET</rptOwnerStreet2>
            <rptOwnerCity>BOONTON</rptOwnerCity>
            <rptOwnerState>NJ</rptOwnerState>
            <rptOwnerZipCode>07005</rptOwnerZipCode>
            <rptOwnerStateDescription></rptOwnerStateDescription>
        </reportingOwnerAddress>
        <reportingOwnerRelationship>
            <isDirector>1</isDirector>
            <isOfficer>0</isOfficer>
            <isTenPercentOwner>0</isTenPercentOwner>
            <isOther>0</isOther>
        </reportingOwnerRelationship>
    </reportingOwner>

    <nonDerivativeTable>
        <nonDerivativeTransaction>
            <securityTitle>
                <value>Common Stock</value>
            </securityTitle>
            <transactionDate>
                <value>2009-01-06</value>
            </transactionDate>
            <transactionCoding>
                <transactionFormType>5</transactionFormType>
                <transactionCode>A</transactionCode>
                <equitySwapInvolved>0</equitySwapInvolved>
                <footnoteId id="F1"/>
            </transactionCoding>
            <transactionAmounts>
                <transactionShares>
                    <value>10345</value>
                </transactionShares>
                <transactionPricePerShare>
                    <value>0.58</value>
                </transactionPricePerShare>
                <transactionAcquiredDisposedCode>
                    <value>A</value>
                </transactionAcquiredDisposedCode>
            </transactionAmounts>
            <postTransactionAmounts>
                <sharesOwnedFollowingTransaction>
                    <value>10345</value>
                </sharesOwnedFollowingTransaction>
            </postTransactionAmounts>
            <ownershipNature>
                <directOrIndirectOwnership>
                    <value>D</value>
                </directOrIndirectOwnership>
            </ownershipNature>
        </nonDerivativeTransaction>
    </nonDerivativeTable>

    <footnotes>
        <footnote id="F1">Grant of restricted shares of common stock on Jan. 6, 2009 as payment of director fees in the amount of $6,000.  Shares vest immediately.</footnote>
    </footnotes>

    <ownerSignature>
        <signatureName>/s/ Marvin Miller</signatureName>
        <signatureDate>2009-01-06</signatureDate>
    </ownerSignature>
</ownershipDocument>
</XML>
</TEXT>
</DOCUMENT>
</SEC-DOCUMENT>
-----END PRIVACY-ENHANCED MESSAGE-----