CONSOLIDATED STATEMENTS OF STOCKHOLDERS' EQUITY - USD ($)	Preferred Stock	Common Stock	Additional paid-in capital	Accumulated other comprehensive gain (loss)	Accumulated deficit	Total
Beginning Balance, Shares at Dec. 31, 2016	0	1,406,002
Compensation on options and restricted stocks issued, Share		5,838
Compensation on options and restricted stocks issued, Amount		$ 12	$ 578,068			$ 578,080
Deemed dividend on preferred stock						0
Unrealized gain on marketable securities				$ 2,525		2,525
Par value adjustment due to reverse stock split		$ (2,683)	2,683			0
Net loss					$ (8,839,682)	(8,839,682)
Ending Balance, Shares at Dec. 31, 2017	0	1,411,840
Ending Balance, Amount at Dec. 31, 2017	$ 0	$ 141	222,397,198	(16,193)	(213,499,285)	8,881,861
Preferred stock sold, net of offering costs, Shares	5,181,346
Preferred stock sold, net of offering costs, Amount	$ 518		8,906,656			8,907,174
Common stock issued for convertible preferred stock, Shares	(2,326,753)	2,326,753
Common stock issued for convertible preferred stock, Amount	$ (233)	$ 233				0
Compensation on options and restricted stocks issued, Share		37,420
Compensation on options and restricted stocks issued, Amount		$ 4	645,193			645,197
Common stock issued for services rendered, Shares		10,241
Common stock issued for services rendered, Amount		$ 1	100,361			100,362
Deemed dividend on preferred stock			7,330,604			7,330,604
Unrealized gain on marketable securities				16,709		16,709
Fractional shares of common stock due to reverse stock split		5,995
Adoption of ASU 2017-11: Reclassification of equity related financial instruments			192,082		(158,409)	33,673
Net loss					(14,144,049)	(14,144,049)
Ending Balance, Shares at Dec. 31, 2018	2,854,593	3,792,249
Ending Balance, Amount at Dec. 31, 2018	$ 285	$ 379	$ 239,572,094	$ 516	$ (227,801,743)	$ 11,771,531