X0202 SCHEDULE 13G/A 0000935836-26-000148 0001792126 XXXXXXXX LIVE 1 Common Stock 03/31/2026 0000034956 Tenax Therapeutics, Inc. 88032L605 101 GLEN LENNOX DRIVE SUITE 300 CHAPEL HILL NC 27517 Rule 13d-1(b) Rule 13d-1(c) Logos Global Management LP b DE 0.00 800000.00 0.00 800000.00 800000.00 N 3.0 IA PN Percentage calculated based on 26,525,159 shares of Common Stock outstanding on May 8, 2026, as reported in the Form 10-Q filed by the Issuer for the quarter ended March 31, 2026. Logos Global Management GP LLC b DE 0.00 800000.00 0.00 800000.00 800000.00 N 3.0 HC OO Percentage calculated based on 26,525,159 shares of Common Stock outstanding on May 8, 2026, as reported in the Form 10-Q filed by the Issuer for the quarter ended March 31, 2026. Logos Global Master Fund LP b E9 0.00 800000.00 0.00 800000.00 800000.00 N 3.0 PN Percentage calculated based on 26,525,159 shares of Common Stock outstanding on May 8, 2026, as reported in the Form 10-Q filed by the Issuer for the quarter ended March 31, 2026. Logos GP LLC b DE 0.00 800000.00 0.00 800000.00 800000.00 N 3.0 HC OO Percentage calculated based on 26,525,159 shares of Common Stock outstanding on May 8, 2026, as reported in the Form 10-Q filed by the Issuer for the quarter ended March 31, 2026. Arsani William b X1 0.00 800000.00 0.00 800000.00 800000.00 N 3.0 HC IN Percentage calculated based on 26,525,159 shares of Common Stock outstanding on May 8, 2026, as reported in the Form 10-Q filed by the Issuer for the quarter ended March 31, 2026. Tenax Therapeutics, Inc. 101 Glen Lennox Drive, Suite 300, Chapel Hill, NC 27517 Logos Global Management LP ("Logos Global") Logos Global Management GP LLC ("Logos Global GP") Logos Global Master Fund LP ("Global Fund") Logos GP LLC ("Logos GP") Arsani William Logos Global is the investment adviser to investment funds, including Global Fund. Logos Global GP is the general partner of Logos Global. Logos GP is the general partner of Global Fund. Dr. William is a control person of Logos Global, Logos Global GP and Logos GP. The reporting persons are filing this statement jointly but not as members of a group, and they expressly disclaim membership in a group. Each reporting person disclaims beneficial ownership of Common Stock except to the extent of that person's pecuniary interest therein. In addition, the filing of this Schedule 13G on behalf of the Global Fund should not be construed as an admission that it is, and it disclaims that it is, a beneficial owner, as defined in Rule 13d-3 under the Act, of any Common Stock covered by this Schedule 13G. One Letterman Drive, Building C, Suite C3-350, San Francisco, California 94129 See Item 4 of the cover sheet for each reporting person. N IA HC Logos Global: 800,000 Logos Global GP: 800,000 Global Fund: 800,000 Logos GP: 800,000 Arsani William: 800,000 Logos Global: 3.0% Logos Global GP: 3.0% Global Fund: 3.0% Logos GP: 3.0% Arsani William: 3.0% Logos Global: 0 Logos Global GP: 0 Global Fund: 0 Logos GP: 0 Arsani William: 0 Logos Global: 800,000 Logos Global GP: 800,000 Global Fund: 800,000 Logos GP: 800,000 Arsani William: 800,000 Logos Global: 0 Logos Global GP: 0 Global Fund: 0 Logos GP: 0 Arsani William: 0 Logos Global: 800,000 Logos Global GP: 800,000 Global Fund: 800,000 Logos GP: 800,000 Arsani William: 800,000 N Y N Global Fund holds the Common Stock for the benefit of its investors and has the right to receive or the power to direct the receipt of dividends from, or the proceeds from the sale of, the Common Stock. Y Y Y N By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were acquired and are held in the ordinary course of business and were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11. By signing below I certify that, to the best of my knowledge and belief, the securities referred to above were not acquired and are not held for the purpose of or with the effect of changing or influencing the control of the issuer of the securities and were not acquired and are not held in connection with or as a participant in any transaction having that purpose or effect, other than activities solely in connection with a nomination under ?? 240.14a-11. EXHIBIT 99.1 - AGREEMENT REGARDING JOINT FILING OF STATEMENT ON SCHEDULE 13D OR 13G Logos Global Management LP /s/ Arsani William 05/15/2026 Logos Global Management GP LLC /s/ Arsani William 05/15/2026 Logos Global Master Fund LP /s/ Arsani William 05/15/2026 Logos GP LLC /s/ Arsani William 05/15/2026 Arsani William /s/ Arsani William 05/15/2026