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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>SUTRO BIOPHARMA INC</name>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>AURA BIOSCIENCES INC</name>
        <lei>N/A</lei>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>AMICUS THERAPEUTICS INC</name>
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          <isin value="US03152W1099"/>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>TWIST BIOSCIENCE CORP</name>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>KRONOS BIO INC</name>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>BIOCRYST PHARMACEUTICALS INC</name>
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        <fairValLevel>1</fairValLevel>
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        <name>UNITED THERAPEUTICS CORP DEL</name>
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          <isin value="US91307C1027"/>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>AMGEN INC</name>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>HALOZYME THERAPEUTICS INC</name>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>IMMUNOGEN INC</name>
        <lei>54930084U0R1OP766Y02</lei>
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        <fairValLevel>1</fairValLevel>
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        <name>SAGE THERAPEUTICS INC</name>
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        <fairValLevel>1</fairValLevel>
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        <name>AXSOME THERAPEUTICS INC</name>
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        <fairValLevel>1</fairValLevel>
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        <name>ABBVIE INC</name>
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        <name>BIOXCEL THERAPEUTICS INC</name>
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        <name>ENTRADA THERAPEUTICS INC</name>
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        <name>BLUEPRINT MEDICINES CORP</name>
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        <name>VIGIL NEUROSCIENCE INC</name>
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        <name>MANNKIND CORP</name>
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        <name>AFFERENT PHARMA</name>
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        <name>ADVERUM BIOTECHNOLOGIES INC</name>
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        <name>GRAPHITE BIO INC</name>
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        <name>CENTESSA PHARMACEUTICALS PLC</name>
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        <title>CENTESSA PHARMACEUTICALS LTD ADR</title>
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        <fairValLevel>1</fairValLevel>
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        <name>FOGHORN THERAPEUTICS INC</name>
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        <title>FOGHORN THERAPEUTICS INC</title>
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      </invstOrSec>
      <invstOrSec>
        <name>ADC THERAPEUTICS SA</name>
        <lei>N/A</lei>
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        <cusip>N/A</cusip>
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          <isin value="CH0499880968"/>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>FUSION PHARMACEUTICALS INC</name>
        <lei>N/A</lei>
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        <invCountry>CA</invCountry>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>KINNATE BIOPHARMA INC</name>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>APPLIED THERAPEUTICS INC</name>
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        <fairValLevel>1</fairValLevel>
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        <name>XENCOR INC</name>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>TREVI THERAPEUTICS INC</name>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>SAREPTA THERAPEUTICS INC</name>
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        <fairValLevel>1</fairValLevel>
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        <name>TG THERAPEUTICS INC</name>
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        <fairValLevel>1</fairValLevel>
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        <name>CRINETICS PHARMACEUTICALS INC</name>
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        <fairValLevel>1</fairValLevel>
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        <name>ABSCI CORP</name>
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        <fairValLevel>1</fairValLevel>
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        <name>TENAYA THERAPEUTICS INC</name>
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        <fairValLevel>1</fairValLevel>
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        <name>ENANTA PHARMACEUTICALS INC</name>
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        <fairValLevel>1</fairValLevel>
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        <name>IVERIC BIO INC</name>
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        <name>THESEUS PHARMACEUTICALS INC</name>
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        <name>INTRA-CELLULAR THERAPIES INC</name>
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        <name>GERON CORP</name>
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        <name>IMMUNOCORE HOLDINGS PLC</name>
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        <name>AFFERENT PHARMA</name>
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        <name>PLIANT THERAPEUTICS INC</name>
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        <name>VALENZABIO INC</name>
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        <title>VALENZABIO INC SER A PC PP</title>
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        <name>INTELLIA THERAPEUTICS INC</name>
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        <title>INTELLIA THERAPEUTICS INC</title>
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        <name>REGENERON PHARMACEUTICALS INC</name>
        <lei>549300RCBFWIRX3HYQ56</lei>
        <title>REGENERON PHARMACEUTICALS INC</title>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      </invstOrSec>
      <invstOrSec>
        <name>PEPGEN INC</name>
        <lei>N/A</lei>
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          <isin value="US7133171055"/>
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        <balance>440591.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>6591241.36000000</valUSD>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>RALLYBIO CORP</name>
        <lei>N/A</lei>
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        <cusip>75120L100</cusip>
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          <isin value="US75120L1008"/>
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        <balance>1550692.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>SALIOGEN THERAPEUTICS INC</name>
        <lei>N/A</lei>
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        <cusip>N/A</cusip>
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          <other otherDesc="Internal" value="IEH140000"/>
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        <curCd>USD</curCd>
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        <assetCat>EP</assetCat>
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        <fairValLevel>3</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      </invstOrSec>
      <invstOrSec>
        <name>ROIVANT SCIENCES LTD</name>
        <lei>549300DL466NY5J6U724</lei>
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        <cusip>N/A</cusip>
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          <other otherDesc="Internal" value="HFC838000"/>
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        <balance>2500000.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>BM</invCountry>

        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>EQRX INC</name>
        <lei>N/A</lei>
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          <other otherDesc="Internal" value="IFC137000"/>
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        <balance>116649.00000000</balance>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>3</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>OMEGA THERAPEUTICS INC</name>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>BIOMARIN PHARMACEUTICAL INC</name>
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          <isin value="US09061G1013"/>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>KORRO BIO INC</name>
        <lei>N/A</lei>
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        <cusip>N/A</cusip>
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          <other otherDesc="Internal" value="IFB621000"/>
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        <assetCat>EP</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>3</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      </invstOrSec>
      <invstOrSec>
        <name>ZENTALIS PHARMACEUTICALS INC</name>
        <lei>N/A</lei>
        <title>ZENTALIS PHARMACEUTICALS LLC</title>
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        <balance>638433.00000000</balance>
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        <curCd>USD</curCd>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>GEMINI THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>GEMINI THERAPEUTICS INC</title>
        <cusip>36870G105</cusip>
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          <isin value="US36870G1058"/>
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        <balance>1555907.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>VERVE THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>VERVE THERAPEUTICS INC</title>
        <cusip>92539P101</cusip>
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          <isin value="US92539P1012"/>
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        <balance>249393.00000000</balance>
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        <curCd>USD</curCd>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>ALDEYRA THERAPEUTICS INC</name>
        <lei>529900HGKY864E4Y9014</lei>
        <title>ALDEYRA THERAPEUTICS INC</title>
        <cusip>01438T106</cusip>
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          <isin value="US01438T1060"/>
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        <balance>961337.00000000</balance>
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        <curCd>USD</curCd>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>PROTHENA CORP PLC</name>
        <lei>5299009ZXQ8NIIJ8OL30</lei>
        <title>PROTHENA CORP PLC</title>
        <cusip>N/A</cusip>
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          <isin value="IE00B91XRN20"/>
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        <balance>761589.00000000</balance>
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        <curCd>USD</curCd>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
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        <invCountry>IE</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>BIOGEN INC</name>
        <lei>W8J5WZB5IY3K0NDQT671</lei>
        <title>BIOGEN INC</title>
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        <balance>703036.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>ARROWHEAD PHARMACEUTICALS INC</name>
        <lei>549300O3CSB8T7OZ3D66</lei>
        <title>ARROWHEAD PHARMACEUTICALS INC</title>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>KRYSTAL BIOTECH INC</name>
        <lei>549300YONUY68210OE41</lei>
        <title>KRYSTAL BIOTECH INC</title>
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        <balance>2105960.00000000</balance>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>ARVINAS INC</name>
        <lei>N/A</lei>
        <title>ARVINAS INC</title>
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      <invstOrSec>
        <name>GH RESEARCH PLC</name>
        <lei>875500HKJS7QQG6EWH62</lei>
        <title>GH RESEARCH PLC</title>
        <cusip>N/A</cusip>
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        <invCountry>IE</invCountry>
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        <fairValLevel>1</fairValLevel>
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        <name>OLINK HOLDING AB</name>
        <lei>8945004Z7ZHV3LML4J27</lei>
        <title>OLINK HOLDING AB ADR</title>
        <cusip>680710100</cusip>
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        <balance>57100.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>SE</invCountry>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>X4 PHARMACEUTICALS INC</name>
        <lei>549300R0UFVPXWP86U94</lei>
        <title>X4 PHARMACEUTICALS INC CL A WT 04/16/2024</title>
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        <assetCat>EC</assetCat>
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      <invstOrSec>
        <name>ARADIGM CORP</name>
        <lei>549300I46MRQ1CGCIY65</lei>
        <title>ARADIGM CORP PIPE</title>
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        <name>SCHOLAR ROCK HOLDING CORP</name>
        <lei>549300Z1FLPGL4OWJ459</lei>
        <title>SCHOLAR ROCK HOLDING CORP</title>
        <cusip>80706P103</cusip>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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        <name>LONGBOARD PHARMACEUTICALS INC</name>
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        <title>LONGBOARD PHARMACEUTICALS INC</title>
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        <balance>371100.00000000</balance>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>NURIX THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>NURIX THERAPEUTICS INC</title>
        <cusip>67080M103</cusip>
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        <balance>1056746.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ARS PHARMACEUTICALS INC</name>
        <lei>N/A</lei>
        <title>ARS PHARMACEUTICALS INC</title>
        <cusip>82835W108</cusip>
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          <isin value="US82835W1080"/>
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        <balance>1675577.00000000</balance>
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        <curCd>USD</curCd>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>KEROS THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>KEROS THERAPEUTICS</title>
        <cusip>492327101</cusip>
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          <isin value="US4923271013"/>
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        <balance>378977.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>APELLIS PHARMACEUTICALS INC</name>
        <lei>254900HS0ZFRXXSB9D42</lei>
        <title>APELLIS PHARMACEUTICALS INC</title>
        <cusip>03753U106</cusip>
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          <isin value="US03753U1060"/>
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        <balance>1431684.00000000</balance>
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        <curCd>USD</curCd>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>ARGENX SE</name>
        <lei>7245009C5FZE6G9ODQ71</lei>
        <title>ARGENX SE SPONSORED ADR</title>
        <cusip>04016X101</cusip>
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          <isin value="US04016X1019"/>
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        <balance>407247.00000000</balance>
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        <curCd>USD</curCd>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>NL</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>ROYALTY PHARMA PLC</name>
        <lei>549300FGFN7VOK8BZR03</lei>
        <title>ROYALTY PHARMA PLC</title>
        <cusip>N/A</cusip>
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          <isin value="GB00BMVP7Y09"/>
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        <balance>285820.00000000</balance>
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        <curCd>USD</curCd>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>GB</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>G1 THERAPEUTICS INC</name>
        <lei>529900TC35UPZQYRKW13</lei>
        <title>G1 THERAPEUTICS INC</title>
        <cusip>3621LQ109</cusip>
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          <isin value="US3621LQ1099"/>
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        <balance>276904.00000000</balance>
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        <curCd>USD</curCd>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>GENERATION BIO CO</name>
        <lei>N/A</lei>
        <title>GENERATION BIO</title>
        <cusip>37148K100</cusip>
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          <isin value="US37148K1007"/>
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        <balance>137100.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>730743.00000000</valUSD>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>CEREVEL THERAPEUTICS HOLDINGS INC</name>
        <lei>254900RJNIRS9COSQR41</lei>
        <title>CEREVEL THERAPEUTICS HOLDINGS INC</title>
        <cusip>15678U128</cusip>
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          <isin value="US15678U1280"/>
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        <balance>1044180.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>INSTIL BIO INC</name>
        <lei>N/A</lei>
        <title>INSTIL BIO INC</title>
        <cusip>45783C101</cusip>
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          <isin value="US45783C1018"/>
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        <balance>1445074.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>CENTURY THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>CENTURY THERAPEUTICS INC</title>
        <cusip>15673T100</cusip>
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          <isin value="US15673T1007"/>
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        <balance>834618.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>REPLIMUNE GROUP INC</name>
        <lei>549300AY704NEIRC4K64</lei>
        <title>REPLIMUNE GROUP INC</title>
        <cusip>76029N106</cusip>
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          <isin value="US76029N1063"/>
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        <balance>910817.00000000</balance>
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        <curCd>USD</curCd>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>SEAGEN INC</name>
        <lei>N/A</lei>
        <title>SEAGEN INC</title>
        <cusip>81181C104</cusip>
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          <isin value="US81181C1045"/>
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        <balance>357732.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>KINIKSA PHARMACEUTICALS LTD</name>
        <lei>N/A</lei>
        <title>KINIKSA PHARMACEUTICALS LTD</title>
        <cusip>N/A</cusip>
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        <assetCat>EC</assetCat>
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        <invCountry>BM</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>CYCLERION THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>CYCLERION THERAPEUTICS INC PP PIPE</title>
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        <assetCat>EC</assetCat>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>DICE THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>DICE MOLECULES HOLDING LLC</title>
        <cusip>23345J104</cusip>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>EDGEWISE THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>EDGEWISE THERAPEUTICS INC</title>
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          <isin value="US28036F1057"/>
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        <balance>1722367.00000000</balance>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>DESIGN THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>DESIGN THERAPEUTICS INC</title>
        <cusip>25056L103</cusip>
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          <isin value="US25056L1035"/>
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        <fairValLevel>1</fairValLevel>
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        <name>ULTRAGENYX PHARMACEUTICAL INC</name>
        <lei>529900EV44GVDN1DCX77</lei>
        <title>ULTRAGENYX PHARMA INC</title>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>ALKERMES PLC</name>
        <lei>N/A</lei>
        <title>ALKERMES PLC</title>
        <cusip>N/A</cusip>
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        <assetCat>EC</assetCat>
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        <invCountry>IE</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>ROCKET PHARMACEUTICALS INC</name>
        <lei>549300R7VV82YUIN4Y93</lei>
        <title>ROCKET PHARMACEUTICALS INC</title>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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        <name>SENSORION SA</name>
        <lei>969500P0W8XJ9CGZDP97</lei>
        <title>SENSORION SA</title>
        <cusip>N/A</cusip>
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          <isin value="FR0012596468"/>
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        <invCountry>FR</invCountry>
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        <fairValLevel>2</fairValLevel>
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      <invstOrSec>
        <name>SELECTA BIOSCIENCES INC</name>
        <lei>529900NMN0LACZOL7C43</lei>
        <title>SELECTA BIOSCIENCES INC</title>
        <cusip>816212104</cusip>
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        <balance>395568.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>SPRINGWORKS THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>SPRINGWORKS THERAPEUTICS INC</title>
        <cusip>85205L107</cusip>
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        <balance>463711.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>MEDAVAIL HOLDINGS INC</name>
        <lei>549300ZNQGSJ2V3ZB668</lei>
        <title>MYOS CORP PIPE</title>
        <cusip>N/A</cusip>
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          <other otherDesc="Internal" value="554051920"/>
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        <balance>2777.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1163.84000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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      </invstOrSec>
      <invstOrSec>
        <name>GUARDANT HEALTH INC</name>
        <lei>254900M8C3E5VC8BR186</lei>
        <title>GUARDANT HEALTH INC</title>
        <cusip>40131M109</cusip>
        <identifiers>
          <isin value="US40131M1099"/>
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        <balance>82500.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>4318050.00000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>POSEIDA THERAPEUTICS INC</name>
        <lei>549300USKSDMNGMN8V04</lei>
        <title>POSEIDA THERAPEUTICS INC</title>
        <cusip>73730P108</cusip>
        <identifiers>
          <isin value="US73730P1084"/>
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        <balance>570083.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>TYRA BIOSCIENCES INC</name>
        <lei>N/A</lei>
        <title>TYRA BIOSCIENCES INC</title>
        <cusip>90240B106</cusip>
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          <isin value="US90240B1061"/>
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        <balance>342201.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>2398829.01000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>CHINOOK THERAPEUTICS INC</name>
        <lei>549300X0O3003W5QYQ48</lei>
        <title>CHINOOK THERAPEUTICS INC</title>
        <cusip>16961L106</cusip>
        <identifiers>
          <isin value="US16961L1061"/>
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        <balance>303781.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>6880639.65000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>ARADIGM CORP</name>
        <lei>549300I46MRQ1CGCIY65</lei>
        <title>ARADIGM CORP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="GDA208000"/>
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        <balance>11945.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>549.47000000</valUSD>
        <pctVal>0.000010269828</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>NOVOCURE LTD</name>
        <lei>213800YPP55UMHWA4826</lei>
        <title>NOVOCURE LTD</title>
        <cusip>N/A</cusip>
        <identifiers>
          <isin value="JE00BYSS4X48"/>
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        <balance>11113.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>853922.92000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>JE</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>UNIQURE N.V.</name>
        <lei>724500RPCTZLFYJZ3S98</lei>
        <title>UNIQURE N.V.</title>
        <cusip>N/A</cusip>
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          <isin value="NL0010696654"/>
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        <balance>255608.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>6763387.68000000</valUSD>
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        <assetCat>EC</assetCat>
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        <invCountry>NL</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>SHATTUCK LABS INC</name>
        <lei>N/A</lei>
        <title>SHATTUCK LABS INC</title>
        <cusip>82024L103</cusip>
        <identifiers>
          <isin value="US82024L1035"/>
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        <balance>110936.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>251824.72000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>AVIDITY BIOSCIENCES INC</name>
        <lei>N/A</lei>
        <title>AVIDITY BIOSCIENCES</title>
        <cusip>05370A108</cusip>
        <identifiers>
          <isin value="US05370A1088"/>
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        <balance>476750.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>5549370.00000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <loanByFundCondition isLoanByFund="Y" loanVal="1473624.00000000"/>
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      <invstOrSec>
        <name>BIONTECH SE</name>
        <lei>894500UZJ5LG1F8J1U58</lei>
        <title>BIONTECH SE ADR</title>
        <cusip>09075V102</cusip>
        <identifiers>
          <isin value="US09075V1026"/>
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        <balance>195228.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>32606980.56000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>DE</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>ARCUTIS BIOTHERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>ARCUTIS BIOTHERAPEUTICS INC</title>
        <cusip>03969K108</cusip>
        <identifiers>
          <isin value="US03969K1088"/>
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        <balance>894174.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>15406618.02000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>INHIBRX INC</name>
        <lei>549300VBKG2LTV1TLY22</lei>
        <title>INHIBRX INC</title>
        <cusip>45720L107</cusip>
        <identifiers>
          <isin value="US45720L1070"/>
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        <balance>254309.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>7624183.82000000</valUSD>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>JANUX THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>JANUX THERAPEUTICS INC</title>
        <cusip>47103J105</cusip>
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          <isin value="US47103J1051"/>
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        <balance>718391.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>9798853.24000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>ALLOGENE THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>ALLOGENE THERAPEUTICS INC</title>
        <cusip>019770106</cusip>
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          <isin value="US0197701065"/>
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        <balance>1556685.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>FATE THERAPEUTICS INC</name>
        <lei>549300L14Q4UHOODLA90</lei>
        <title>FATE THERAPEUTICS INC</title>
        <cusip>31189P102</cusip>
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          <isin value="US31189P1021"/>
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        <balance>608787.00000000</balance>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>RELAY THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>RELAY THERAPEUTICS INC</title>
        <cusip>75943R102</cusip>
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          <isin value="US75943R1023"/>
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        <balance>770589.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>14317543.62000000</valUSD>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>PRELUDE THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>PRELUDE THERAPEUTICS INC</title>
        <cusip>74065P101</cusip>
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          <isin value="US74065P1012"/>
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        <balance>359156.00000000</balance>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>REVOLUTION MEDICINES INC</name>
        <lei>549300JU3X0LBCQ65892</lei>
        <title>REVOLUTION MEDICINES INC</title>
        <cusip>76155X100</cusip>
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          <isin value="US76155X1000"/>
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        <balance>418772.00000000</balance>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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        <name>BRIDGEBIO PHARMA INC</name>
        <lei>54930028YG89VTY2J114</lei>
        <title>BRIDGEBIO PHARMA INC</title>
        <cusip>10806X102</cusip>
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        <balance>613842.00000000</balance>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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        <name>GOSSAMER BIO INC</name>
        <lei>549300ZOC0N2W6PSFR58</lei>
        <title>GOSSAMER BIO INC</title>
        <cusip>38341P102</cusip>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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        <name>CINCOR PHARMA INC</name>
        <lei>N/A</lei>
        <title>CINCOR PHARMA INC</title>
        <cusip>17240Y109</cusip>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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        <name>NUVATION BIO INC</name>
        <lei>N/A</lei>
        <title>NUVATION BIO INC</title>
        <cusip>67080N101</cusip>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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        <name>SCHRODINGER INC</name>
        <lei>N/A</lei>
        <title>SCHRODINGER INC</title>
        <cusip>80810D103</cusip>
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        <balance>199427.00000000</balance>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>INCYTE CORP</name>
        <lei>549300Z4WN6JVZ3T4680</lei>
        <title>INCYTE CORP</title>
        <cusip>45337C102</cusip>
        <identifiers>
          <isin value="US45337C1027"/>
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        <balance>427600.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>34066892.00000000</valUSD>
        <pctVal>0.636724752400</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>VAXCYTE INC</name>
        <lei>254900M7NMHTGASX8D95</lei>
        <title>VAXCYTE INC</title>
        <cusip>92243G108</cusip>
        <identifiers>
          <isin value="US92243G1085"/>
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        <balance>1355250.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>62422815.00000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>MODERNA INC</name>
        <lei>549300EI6OKH5K5Q2G38</lei>
        <title>MODERNA INC</title>
        <cusip>60770K107</cusip>
        <identifiers>
          <isin value="US60770K1079"/>
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        <balance>918386.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>161553281.26000000</valUSD>
        <pctVal>3.019499783241</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>ORIC PHARMACEUTICALS INC</name>
        <lei>54930033FJRNEYBW0L25</lei>
        <title>ORIC PHARMACEUTICALS INC</title>
        <cusip>68622P109</cusip>
        <identifiers>
          <isin value="US68622P1093"/>
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        <balance>148239.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>532178.01000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>HORIZON THERAPEUTICS PLC</name>
        <lei>N/A</lei>
        <title>HORIZON THERAPEUTICS PLC</title>
        <cusip>N/A</cusip>
        <identifiers>
          <isin value="IE00BQPVQZ61"/>
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        <balance>320147.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>32107542.63000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>IE</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>BIOINVENT INTERNATIONAL AB</name>
        <lei>549300E7QRHEF2IJUY10</lei>
        <title>BIOINVENT AB</title>
        <cusip>N/A</cusip>
        <identifiers>
          <isin value="SE0015244520"/>
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        <balance>788706.00000000</balance>
        <units>NS</units>
        <currencyConditional curCd="SEK" exchangeRt="10.50185000"/>
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        <pctVal>0.050620232469</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>SE</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>TANGO THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>TANGO THERAPEUTICS INC</title>
        <cusip>87583X109</cusip>
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          <isin value="US87583X1090"/>
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        <balance>1463188.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>10988541.88000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>PROMETHEUS BIOSCIENCES INC</name>
        <lei>N/A</lei>
        <title>PROMETHEUS BIOSCIENCES INC</title>
        <cusip>74349U108</cusip>
        <identifiers>
          <isin value="US74349U1088"/>
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        <balance>342555.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>14082436.05000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>ALPHA TAU MEDICAL LTD</name>
        <lei>N/A</lei>
        <title>ALPHA TAU MEDICAL LTD CL A</title>
        <cusip>N/A</cusip>
        <identifiers>
          <isin value="IL0011839383"/>
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        <balance>362046.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1444563.54000000</valUSD>
        <pctVal>0.026999509151</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>IL</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <loanByFundCondition isLoanByFund="Y" loanVal="146433.00000000"/>
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      <invstOrSec>
        <name>CANDEL THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>CANDEL THERAPEUTICS INC</title>
        <cusip>137404109</cusip>
        <identifiers>
          <isin value="US1374041093"/>
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        <balance>737596.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1290793.00000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <loanByFundCondition isLoanByFund="Y" loanVal="19075.00000000"/>
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      <invstOrSec>
        <name>23ANDME HOLDING CO</name>
        <lei>N/A</lei>
        <title>23ANDME HOLDING CO CL A</title>
        <cusip>90138Q108</cusip>
        <identifiers>
          <isin value="US90138Q1085"/>
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        <balance>2046974.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>6243270.70000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <loanByFundCondition isLoanByFund="Y" loanVal="4393830.00000000"/>
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      <invstOrSec>
        <name>VERA THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>VERA THERAPEUTICS INC</title>
        <cusip>92337R101</cusip>
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          <isin value="US92337R1014"/>
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        <balance>779768.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>13022125.60000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>VERONA PHARMA PLC</name>
        <lei>213800EVI6O6J3TIAL06</lei>
        <title>VERONA PHARMA PLC ADR</title>
        <cusip>925050106</cusip>
        <identifiers>
          <isin value="US9250501064"/>
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        <balance>290000.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>3741000.00000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>GB</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>IDORSIA LTD</name>
        <lei>506700XOVZUB107S5720</lei>
        <title>IDORSIA LTD</title>
        <cusip>N/A</cusip>
        <identifiers>
          <isin value="CH0363463438"/>
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        <balance>1092661.00000000</balance>
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        <currencyConditional curCd="CHF" exchangeRt="0.94625000"/>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>CH</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>EVELO BIOSCIENCES INC</name>
        <lei>N/A</lei>
        <title>EVELO BIOSCIENCES INC</title>
        <cusip>299734103</cusip>
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          <isin value="US2997341035"/>
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        <balance>1098999.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>2296907.91000000</valUSD>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>CYTEIR THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>CYTEIR THERAPEUTICS INC</title>
        <cusip>23284P103</cusip>
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          <isin value="US23284P1030"/>
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        <balance>451123.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>649617.12000000</valUSD>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>ATEA PHARMACEUTICALS INC</name>
        <lei>N/A</lei>
        <title>ATEA PHARMACEUTICALS INC</title>
        <cusip>04683R106</cusip>
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          <isin value="US04683R1068"/>
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        <balance>66800.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>313292.00000000</valUSD>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>ALLOVIR INC</name>
        <lei>N/A</lei>
        <title>ALLOVIR INC</title>
        <cusip>019818103</cusip>
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          <isin value="US0198181036"/>
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        <balance>852383.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>6401396.33000000</valUSD>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>KORRO BIO INC</name>
        <lei>N/A</lei>
        <title>KORRO BIO INC SER B-1 PC PP</title>
        <cusip>N/A</cusip>
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          <other otherDesc="Internal" value="IFB620000"/>
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        <assetCat>EP</assetCat>
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        <fairValLevel>3</fairValLevel>
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      <invstOrSec>
        <name>VERRICA PHARMACEUTICALS INC</name>
        <lei>5493002L68H6THU5GW50</lei>
        <title>VERRICA PHARMACEUTICALS INC</title>
        <cusip>92511W108</cusip>
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        <balance>1597876.00000000</balance>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>EQRX INC</name>
        <lei>N/A</lei>
        <title>EQRX INC 2 YR EARNOUT (CVR) RT</title>
        <cusip>N/A</cusip>
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          <other otherDesc="Internal" value="IFC139000"/>
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        <balance>49993.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>132981.38000000</valUSD>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>3</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>ROIVANT SCIENCES LTD</name>
        <lei>549300DL466NY5J6U724</lei>
        <title>ROIVANT SCIENCES LTD</title>
        <cusip>N/A</cusip>
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          <isin value="BMG762791017"/>
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        <balance>5957525.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>31932334.00000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>BM</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>REPARE THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>REPARE THERAPEUTICS INC</title>
        <cusip>760273102</cusip>
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          <isin value="US7602731025"/>
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        <balance>174960.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>2804608.80000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>CA</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>IKENA ONCOLOGY INC</name>
        <lei>N/A</lei>
        <title>IKENA ONCOLOGY INC</title>
        <cusip>45175G108</cusip>
        <identifiers>
          <isin value="US45175G1085"/>
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        <balance>416547.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>928899.81000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>HOOKIPA PHARMA INC</name>
        <lei>N/A</lei>
        <title>HOOKIPA PHARMA INC</title>
        <cusip>43906K100</cusip>
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          <isin value="US43906K1007"/>
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        <balance>1480200.00000000</balance>
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        <curCd>USD</curCd>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      </invstOrSec>
      <invstOrSec>
        <name>KARUNA THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>KARUNA THERAPEUTICS INC</title>
        <cusip>48576A100</cusip>
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          <isin value="US48576A1007"/>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      </invstOrSec>
      <invstOrSec>
        <name>AEROVATE THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>AEROVATE THERAPEUTICS INC</title>
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          <isin value="US0080641071"/>
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        <balance>77051.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>PROTAGONIST THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>PROTAGONIST THERAPEUTICS INC</title>
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          <isin value="US74366E1029"/>
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        <balance>144827.00000000</balance>
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        <curCd>USD</curCd>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>VENTYX BIOSCIENCES INC</name>
        <lei>N/A</lei>
        <title>VENTYX BIOSCIENCES INC</title>
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          <isin value="US92332V1070"/>
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        <balance>716630.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>CYTOKINETICS INC</name>
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          <isin value="US23282W6057"/>
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        <balance>2154571.00000000</balance>
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        <curCd>USD</curCd>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>ATYR PHARMA INC</name>
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          <isin value="US0021202025"/>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>NATIONAL RESILIENCE INC</name>
        <lei>N/A</lei>
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        <cusip>N/A</cusip>
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          <other otherDesc="Internal" value="GII424000"/>
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        <curCd>USD</curCd>
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        <assetCat>EP</assetCat>
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        <fairValLevel>3</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>SCHOLAR ROCK HOLDING CORP</name>
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        <cusip>N/A</cusip>
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          <other otherDesc="Internal" value="JJW836000"/>
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        <assetCat>EC</assetCat>
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        <fairValLevel>2</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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        <name>ALECTOR INC</name>
        <lei>549300Z8RQOIY1JMHC25</lei>
        <title>ALECTOR INC</title>
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        <assetCat>EC</assetCat>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>ARISTEA THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>ARISTEA THERAPEUTICS INC SER B PC PP</title>
        <cusip>N/A</cusip>
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        <assetCat>EP</assetCat>
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        <fairValLevel>3</fairValLevel>
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      <invstOrSec>
        <name>AMBRX BIOPHARMA INC</name>
        <lei>N/A</lei>
        <title>AMBRX BIOPHARMA INC ADR</title>
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        <assetCat>EC</assetCat>
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        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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        <name>ORAGENICS INC</name>
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        <title>ORAGENICS INC PIPE</title>
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        <fairValLevel>1</fairValLevel>
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        <name>Fidelity Revere Street Trust</name>
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        <title>Fidelity Cash Central Fund</title>
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        <assetCat>STIV</assetCat>
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        <fairValLevel>1</fairValLevel>
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        <name>WAVE LIFE SCIENCES LTD</name>
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        <title>WAVE LIFE SCIENCES LTD</title>
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        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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        <name>ASCENDIS PHARMA A/S</name>
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        <title>ASCENDIS PHARMA AS SPON ADR</title>
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        <fairValLevel>1</fairValLevel>
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        <name>LEGEND BIOTECH CORP</name>
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        <title>LEGEND BIOTECH CORP SPON ADR</title>
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        <fairValLevel>1</fairValLevel>
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        <name>4D MOLECULAR THERAPEUTICS INC</name>
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        <name>GERON CORP</name>
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        <title>GERON CORP</title>
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        <name>RECURSION PHARMACEUTICALS INC</name>
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        <name>VOR BIOPHARMA INC</name>
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        <name>ADICET BIO INC</name>
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        <title>ADICET BIO INC</title>
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        <fairValLevel>1</fairValLevel>
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        <name>COMPASS THERAPEUTICS INC</name>
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        <fairValLevel>1</fairValLevel>
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        <name>RAIN THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>RAIN THERAPEUTICS INC</title>
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        <fairValLevel>1</fairValLevel>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>REGULUS THERAPEUTICS INC</name>
        <lei>529900ZYH2KYFH6Z7098</lei>
        <title>REGULUS THERAPEUTICS INC</title>
        <cusip>75915K309</cusip>
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          <isin value="US75915K3095"/>
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        <balance>2195000.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>3753450.00000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      </invstOrSec>
      <invstOrSec>
        <name>VERTEX PHARMACEUTICALS INC</name>
        <lei>54930015RAQRRZ5ZGJ91</lei>
        <title>VERTEX PHARMACEUTICALS INC</title>
        <cusip>92532F100</cusip>
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          <isin value="US92532F1003"/>
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        <balance>709810.00000000</balance>
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        <curCd>USD</curCd>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      </invstOrSec>
      <invstOrSec>
        <name>REATA PHARMACEUTICALS INC</name>
        <lei>5299005F094GH9QDDD80</lei>
        <title>REATA PHARMACEUTICALS INC CL A</title>
        <cusip>75615P103</cusip>
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          <isin value="US75615P1030"/>
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        <balance>381628.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      </invstOrSec>
      <invstOrSec>
        <name>SCORPION THERAPEUTICS INC</name>
        <lei>N/A</lei>
        <title>SCORPION THERAPEUTICS INC SER B PC PP</title>
        <cusip>N/A</cusip>
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          <other otherDesc="Internal" value="HAD933000"/>
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        <balance>3099905.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EP</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>3</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>BIOHAVEN LTD</name>
        <lei>N/A</lei>
        <title>BIOHAVEN LTD</title>
        <cusip>N/A</cusip>
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          <isin value="VGG1110E1079"/>
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        <balance>2823752.00000000</balance>
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        <curCd>USD</curCd>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
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        <invCountry>VG</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>AXCELLA HEALTH INC</name>
        <lei>N/A</lei>
        <title>AXCELLA HEALTH INC</title>
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          <isin value="US05454B1052"/>
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        <balance>1661354.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>NATERA INC</name>
        <lei>N/A</lei>
        <title>NATERA INC</title>
        <cusip>632307104</cusip>
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          <isin value="US6323071042"/>
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        <balance>356133.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>OPTINOSE INC</name>
        <lei>549300CPBME7Z3CYMN16</lei>
        <title>OPTINOSE INC WT 11/23/27</title>
        <cusip>68404V118</cusip>
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          <isin value="US68404V1180"/>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>2</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>PHARVARIS BV</name>
        <lei>9845003BE146D3B75D32</lei>
        <title>PHARVARIS BV</title>
        <cusip>N/A</cusip>
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          <isin value="NL00150005Y4"/>
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        <balance>353507.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>NL</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>NKARTA INC</name>
        <lei>N/A</lei>
        <title>NKARTA INC</title>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>MADRIGAL PHARMACEUTICALS INC</name>
        <lei>549300CHIMT2EUSNJB60</lei>
        <title>MADRIGAL PHARMACEUTICALS INC</title>
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          <isin value="US5588681057"/>
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        <balance>153140.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>BELLUS HEALTH INC NEW</name>
        <lei>549300QZYQDSMOXCP667</lei>
        <title>BELLUS HEALTH INC</title>
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          <isin value="CA07987C2040"/>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>CA</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>ICOSAVAX INC</name>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>PTC THERAPEUTICS INC</name>
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        <fairValLevel>1</fairValLevel>
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        <name>CODIAK BIOSCIENCES INC</name>
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        <title>CODIAK BIOSCIENCES INC</title>
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        <fairValLevel>1</fairValLevel>
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        <name>BICYCLE THERAPEUTICS PLC</name>
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        <title>BICYCLE THERAPEUTICS LTD ADR</title>
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        <fairValLevel>1</fairValLevel>
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        <name>IMMUNEERING CORP</name>
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        <name>ARCELLX INC</name>
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        <name>STOKE THERAPEUTICS INC</name>
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        <title>STOKE THERAPEUTICS INC</title>
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        <name>DAY ONE BIOPHARMACEUTICALS INC</name>
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        <name>UCB SA</name>
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        <name>RHYTHM PHARMACEUTICALS INC</name>
        <lei>529900JPNWXQ8DPLA551</lei>
        <title>RHYTHM PHARMACEUTICALS INC</title>
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        <name>DYNE THERAPEUTICS INC</name>
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        <title>DYNE THERAPEUTICS INC</title>
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        <name>SERES THERAPEUTICS INC</name>
        <lei>549300GMXBE5NUWISF13</lei>
        <title>SERES THERAPEUTICS INC</title>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>SPRINGWORKS THERAPEUTICS INC</name>
        <lei>N/A</lei>
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        <cusip>N/A</cusip>
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          <other otherDesc="Internal" value="JLJ198000"/>
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      <invstOrSec>
        <name>IGM BIOSCIENCES INC</name>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>ALNYLAM PHARMACEUTICALS INC</name>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>HARMONY BIOSCIENCES HOLDINGS INC</name>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>ZEALAND PHARMA A/S</name>
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        <fairValLevel>2</fairValLevel>
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      <invstOrSec>
        <name>CORCEPT THERAPEUTICS INC</name>
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        <fairValLevel>1</fairValLevel>
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        <name>Fidelity Revere Street Trust</name>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>CODIAK BIOSCIENCES INC</name>
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        <fairValLevel>2</fairValLevel>
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      <invstOrSec>
        <name>KYMERA THERAPEUTICS INC</name>
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      <invstOrSec>
        <name>OPTINOSE INC</name>
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        <fairValLevel>1</fairValLevel>
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        <name>MIRATI THERAPEUTICS INC</name>
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        <title>Mirati Therapeutics Inc</title>
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        <fairValLevel>1</fairValLevel>
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        <name>BEAM THERAPEUTICS INC</name>
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        <fairValLevel>1</fairValLevel>
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        <name>XENON PHARMACEUTICALS INC</name>
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        <fairValLevel>1</fairValLevel>
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        <name>TRAVERE THERAPEUTICS INC</name>
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        <name>ANAPTYSBIO INC</name>
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        <name>COGENT BIOSCIENCES INC</name>
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        <name>DENALI THERAPEUTICS INC</name>
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        <name>CYCLERION THERAPEUTICS INC</name>
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        <name>GRITSTONE BIO INC</name>
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        <title>GRITSTONE BIO INC</title>
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        <name>INSMED INC</name>
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        <name>GILEAD SCIENCES INC</name>
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        <title>GILEAD SCIENCES INC</title>
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        <name>ALX ONCOLOGY HOLDINGS INC</name>
        <lei>N/A</lei>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      </invstOrSec>
      <invstOrSec>
        <name>TAYSHA GENE THERAPIES INC</name>
        <lei>N/A</lei>
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          <isin value="US8776191061"/>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>ALLENA PHARMACEUTICALS INC</name>
        <lei>549300749HO5QS40BX97</lei>
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          <isin value="US0181191075"/>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>MORPHOSYS AG</name>
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        <assetCat>EC</assetCat>
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        <invCountry>DE</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>BIOMEA FUSION INC</name>
        <lei>N/A</lei>
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          <isin value="US09077A1060"/>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>MERUS NV</name>
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          <isin value="NL0011606264"/>
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        <balance>458686.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>NL</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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        <name>ERASCA INC</name>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>CELLDEX THERAPEUTICS INC</name>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>ELEVATEBIO, LLC</name>
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        <title>ELEVATEBIO LLC SER C PC PP</title>
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        <fairValLevel>3</fairValLevel>
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      <invstOrSec>
        <name>IONIS PHARMACEUTICALS INC</name>
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        <fairValLevel>1</fairValLevel>
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        <name>NUVALENT INC</name>
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        <fairValLevel>1</fairValLevel>
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        <name>MONTE ROSA THERAPEUTICS INC</name>
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        <fairValLevel>1</fairValLevel>
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        <name>2SEVENTY BIO INC</name>
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        <fairValLevel>1</fairValLevel>
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        <name>ARCUS BIOSCIENCES INC</name>
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        <fairValLevel>1</fairValLevel>
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        <name>ARCTURUS THERAPEUTICS HOLDINGS INC</name>
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        <name>SEER INC</name>
        <lei>N/A</lei>
        <title>SEER INC</title>
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      <invstOrSec>
        <name>RAPT THERAPEUTICS INC</name>
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      <invstOrSec>
        <name>FULCRUM THERAPEUTICS INC</name>
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      </invstOrSec>
    </invstOrSecs>
    <signature>
      <ncom:dateSigned>2022-12-30</ncom:dateSigned>
      <ncom:nameOfApplicant>Stacie M. Smith</ncom:nameOfApplicant>
      <ncom:signature>Stacie M. Smith</ncom:signature>
      <ncom:signerName>Stacie M. Smith</ncom:signerName>
      <ncom:title>President and Treasurer</ncom:title>
    </signature>
  </formData>
  <documents>XXXX</documents>
</edgarSubmission>
