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        <curCd>USD</curCd>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>ARGENX SE</name>
        <lei>7245009C5FZE6G9ODQ71</lei>
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          <isin value="NL0010832176"/>
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        <balance>17400.00000000</balance>
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        <fairValLevel>2</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>ZOETIS INC</name>
        <lei>549300HD9Q1LOC9KLJ48</lei>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>MIRATI THERAPEUTICS INC</name>
        <lei>529900GYRW59IDQV6N54</lei>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>HORIZON THERAPEUTICS PLC</name>
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          <isin value="IE00BQPVQZ61"/>
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        <invCountry>IE</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>REATA PHARMACEUTICALS INC</name>
        <lei>5299005F094GH9QDDD80</lei>
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          <isin value="US75615P1030"/>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>PTC THERAPEUTICS INC</name>
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          <isin value="US69366J2006"/>
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        <assetCat>EC</assetCat>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>LILLY (ELI) and CO</name>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>AMGEN INC</name>
        <lei>62QBXGPJ34PQ72Z12S66</lei>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>KANGJI MEDICAL HOLDINGS LTD</name>
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        <title>KANGJI MEDICAL HOLDINGS LTD(180 DAY LOCK UP)</title>
        <cusip>N/A</cusip>
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        <invCountry>KY</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
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      <invstOrSec>
        <name>BRISTOL-MYERS SQUIBB CO</name>
        <lei>HLYYNH7UQUORYSJQCN42</lei>
        <title>BRISTOL-MYERS SQUIBB CO</title>
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          <isin value="US1101221083"/>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>ELANCO ANIMAL HEALTH INC</name>
        <lei>549300SHPNDCE059M934</lei>
        <title>ELANCO ANIMAL HEALTH INC</title>
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          <isin value="US28414H1032"/>
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        <balance>225100.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>HARMONY BIOSCIENCES HOLDINGS INC</name>
        <lei>N/A</lei>
        <title>HARMONY BIOSCIENCES II INC(180 DAY LOCK UP)</title>
        <cusip>N/A</cusip>
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          <other otherDesc="Internal" value="GEH391000"/>
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        <balance>137426.00000000</balance>
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        <assetCat>EC</assetCat>
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        <fairValLevel>2</fairValLevel>
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      <invstOrSec>
        <name>ASCENDIS PHARMA A/S</name>
        <lei>549300B66JN3W3J8GH73</lei>
        <title>ASCENDIS PHARMA AS SPON ADR</title>
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        <balance>51300.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>DK</invCountry>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>BOSTON SCIENTIFIC CORP</name>
        <lei>Y6ZDD9FP4P8JSSJMW954</lei>
        <title>BOSTON SCIENTIFIC CORP</title>
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        <balance>149600.00000000</balance>
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        <assetCat>EC</assetCat>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>RICHTER GEDEON PLC</name>
        <lei>549300J6ZJW5IH4WEE46</lei>
        <title>RICHTER GEDEON VEGYESZETI NY</title>
        <cusip>N/A</cusip>
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        <balance>157700.00000000</balance>
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        <assetCat>EC</assetCat>
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        <invCountry>HU</invCountry>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>CHEMOCENTRYX INC</name>
        <lei>529900YTTXUSFQTAKY40</lei>
        <title>CHEMOCENTRYX INC</title>
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        <balance>6000.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>INNOVENT BIOLGICS INC</name>
        <lei>25490058ONL9SCIE1R22</lei>
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      <invstOrSec>
        <name>HARMONY BIOSCIENCES HOLDINGS INC</name>
        <lei>N/A</lei>
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        <assetCat>EC</assetCat>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>INTRA-CELLULAR THERAPIES INC</name>
        <lei>5299002U2KGF193IJA20</lei>
        <title>INTRA-CELLULAR THERAPIES INC</title>
        <cusip>46116X101</cusip>
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        <balance>107000.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>1949540.00000000</valUSD>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>XENCOR INC</name>
        <lei>549300V5IF65437JKG30</lei>
        <title>XENCOR INC</title>
        <cusip>98401F105</cusip>
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          <isin value="US98401F1057"/>
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        <balance>49568.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1772056.00000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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        <name>BRUKER CORP</name>
        <lei>LEBZ6VLQ6I8XB1NHVY15</lei>
        <title>BRUKER CORP</title>
        <cusip>116794108</cusip>
        <identifiers>
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        <balance>117100.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>4920542.00000000</valUSD>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>ZOGENIX INC</name>
        <lei>54930089H3HF4C32SK78</lei>
        <title>ZOGENIX INC</title>
        <cusip>98978L204</cusip>
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          <isin value="US98978L2043"/>
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        <balance>31800.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>752706.00000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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        <name>NEKTAR THERAPEUTICS</name>
        <lei>5299005I24806IOIYE03</lei>
        <title>NEKTAR THERAPEUTICS</title>
        <cusip>640268108</cusip>
        <identifiers>
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        <balance>368233.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>7121626.22000000</valUSD>
        <pctVal>0.790789126139</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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      </invstOrSec>
      <invstOrSec>
        <name>MERCK and CO INC NEW</name>
        <lei>4YV9Y5M8S0BRK1RP0397</lei>
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        <cusip>58933Y105</cusip>
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          <isin value="US58933Y1055"/>
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        <balance>517336.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>UCB SA</name>
        <lei>2138008J191VLSGY5A09</lei>
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        <cusip>N/A</cusip>
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          <isin value="BE0003739530"/>
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        <balance>181600.00000000</balance>
        <units>NS</units>
        <currencyConditional curCd="EUR" exchangeRt="0.83797712"/>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>BE</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>MAGENTA THERAPEUTICS INC</name>
        <lei>549300Z3N6ODPCOFC890</lei>
        <title>MAGENTA THERAPEUTICS INC</title>
        <cusip>55910K108</cusip>
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          <isin value="US55910K1088"/>
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        <balance>97400.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>708098.00000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>BECTON DICKINSON and CO</name>
        <lei>ICE2EP6D98PQUILVRZ91</lei>
        <title>BECTON DICKINSON and CO</title>
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          <isin value="US0758871091"/>
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        <balance>50500.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>12259885.00000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>KALVISTA PHARMACEUTICALS INC</name>
        <lei>529900Q7IDA3WUGRZA51</lei>
        <title>KALVISTA PHARMACEUTICALS INC</title>
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          <isin value="US4834971032"/>
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        <balance>99000.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>1296900.00000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>BAUSCH HEALTH COS INC</name>
        <lei>B3BS7ACMDUWISF18KY76</lei>
        <title>BAUSCH HEALTH COS INC</title>
        <cusip>071734107</cusip>
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          <isin value="CA0717341071"/>
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        <balance>560600.00000000</balance>
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        <currencyConditional curCd="CAD" exchangeRt="1.30435000"/>
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        <pctVal>1.033233228736</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>CA</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>OLIVO LABS LLC</name>
        <lei>N/A</lei>
        <title>OLIVO LABS</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="BEA861000"/>
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        <balance>6851.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>0.07000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>ATHENEX INC</name>
        <lei>5493001V4L0Q5EPPOH52</lei>
        <title>ATHENEX INC</title>
        <cusip>04685N103</cusip>
        <identifiers>
          <isin value="US04685N1037"/>
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        <balance>166800.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1916532.00000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
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      <invstOrSec>
        <name>BLUEPRINT MEDICINES CORP</name>
        <lei>5299004CC60O9T5HVM83</lei>
        <title>BLUEPRINT MEDICINES CORP</title>
        <cusip>09627Y109</cusip>
        <identifiers>
          <isin value="US09627Y1091"/>
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        <balance>60700.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>4700001.00000000</valUSD>
        <pctVal>0.521890586339</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>VERTEX PHARMACEUTICALS INC</name>
        <lei>54930015RAQRRZ5ZGJ91</lei>
        <title>VERTEX PHARMACEUTICALS INC</title>
        <cusip>92532F100</cusip>
        <identifiers>
          <isin value="US92532F1003"/>
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        <balance>33700.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>9406344.00000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>ALLOVIR INC</name>
        <lei>N/A</lei>
        <title>ALLOVIR INC</title>
        <cusip>019818103</cusip>
        <identifiers>
          <isin value="US0198181036"/>
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        <balance>5100.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>165189.00000000</valUSD>
        <pctVal>0.018342673558</pctVal>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>GENERATION BIO</name>
        <lei>N/A</lei>
        <title>GENERATION BIO(180 DAY LOCKUP)</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="GBJ456000"/>
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        <balance>7473.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>210043.61000000</valUSD>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>CATALENT INC</name>
        <lei>N/A</lei>
        <title>CATALENT INC</title>
        <cusip>148806102</cusip>
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          <isin value="US1488061029"/>
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        <balance>75400.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>6974500.00000000</valUSD>
        <pctVal>0.774452153185</pctVal>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>GLOBAL BLOOD THERAPEUTICS INC</name>
        <lei>549300U4G0QKK99GRT15</lei>
        <title>GLOBAL BLOOD THERAPEUTICS INC</title>
        <cusip>37890U108</cusip>
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        <balance>166300.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
        <securityLending>
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      <invstOrSec>
        <name>GLAXOSMITHKLINE PLC</name>
        <lei>5493000HZTVUYLO1D793</lei>
        <title>GLAXOSMITHKLINE PLC SPONS ADR</title>
        <cusip>37733W105</cusip>
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          <isin value="US37733W1053"/>
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        <balance>628200.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>GB</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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        <name>BIONTECH SE</name>
        <lei>894500UZJ5LG1F8J1U58</lei>
        <title>BIONTECH SE ADR</title>
        <cusip>09075V102</cusip>
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          <isin value="US09075V1026"/>
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        <balance>50148.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>3071565.00000000</valUSD>
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        <assetCat>EC</assetCat>
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        <invCountry>DE</invCountry>
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        <fairValLevel>1</fairValLevel>
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        <name>MYOS RENS TECHNOLOGY INC</name>
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        <title>MYOS CORP PIPE</title>
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        <balance>40000.00000000</balance>
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        <curCd>USD</curCd>
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        <name>Fidelity Revere Street Trust</name>
        <lei>549300BDV45LJNXBZC55</lei>
        <title>Fidelity Cash Central Fund</title>
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        <name>GENERATION BIO</name>
        <lei>N/A</lei>
        <title>GENERATION BIO</title>
        <cusip>37148K100</cusip>
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          <isin value="US37148K1007"/>
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        <balance>16738.00000000</balance>
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        <curCd>USD</curCd>
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      <invstOrSec>
        <name>ASTRAZENECA PLC</name>
        <lei>PY6ZZQWO2IZFZC3IOL08</lei>
        <title>ASTRAZENECA PLC SPONS ADR</title>
        <cusip>046353108</cusip>
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          <isin value="US0463531089"/>
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        <balance>1711700.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>GB</invCountry>
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        <fairValLevel>1</fairValLevel>
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        <name>JOHNSON and JOHNSON</name>
        <lei>549300G0CFPGEF6X2043</lei>
        <title>JOHNSON and JOHNSON</title>
        <cusip>478160104</cusip>
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        <fairValLevel>1</fairValLevel>
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        <name>SAREPTA THERAPEUTICS INC</name>
        <lei>549300IKDPIED8J8IG21</lei>
        <title>SAREPTA THERAPEUTICS INC</title>
        <cusip>803607100</cusip>
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        <balance>18441.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>2700131.22000000</valUSD>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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        <name>SANOFI</name>
        <lei>549300E9PC51EN656011</lei>
        <title>SANOFI SPON ADR</title>
        <cusip>80105N105</cusip>
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        <balance>1652122.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>FR</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>LEAP THERAPEUTICS INC</name>
        <lei>549300T31SMMJ2DDLI13</lei>
        <title>LEAP THERAPEUTICS INC WT</title>
        <cusip>N/A</cusip>
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        <balance>606000.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>436344.24000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ROCHE HOLDING LTD</name>
        <lei>549300U41AUUVOAAOB37</lei>
        <title>ROCHE HOLDINGS AG (GENUSSCHEINE)</title>
        <cusip>N/A</cusip>
        <identifiers>
          <isin value="CH0012032048"/>
        </identifiers>
        <balance>198096.00000000</balance>
        <units>NS</units>
        <currencyConditional curCd="CHF" exchangeRt="0.90395000"/>
        <valUSD>69297751.42000000</valUSD>
        <pctVal>7.694858813985</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>CH</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ASTELLAS PHARMA INC</name>
        <lei>529900IB708DY2HBBB35</lei>
        <title>ASTELLAS PHARMA INC</title>
        <cusip>N/A</cusip>
        <identifiers>
          <isin value="JP3942400007"/>
        </identifiers>
        <balance>601900.00000000</balance>
        <units>NS</units>
        <currencyConditional curCd="JPY" exchangeRt="105.91500000"/>
        <valUSD>9442702.33000000</valUSD>
        <pctVal>1.048522639810</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>JP</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>PERRIGO CO PLC</name>
        <lei>549300IFOQS6R1QLY196</lei>
        <title>PERRIGO CO PLC</title>
        <cusip>N/A</cusip>
        <identifiers>
          <isin value="IE00BGH1M568"/>
        </identifiers>
        <balance>257800.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>13482940.00000000</valUSD>
        <pctVal>1.497152758516</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>IE</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>Fidelity Revere Street Trust</name>
        <lei>549300BDV45LJNXBZC55</lei>
        <title>Fidelity Securities Lending Cash Central Fund</title>
        <cusip>31635A303</cusip>
        <identifiers>
          <isin value="US31635A3032"/>
        </identifiers>
        <balance>17437364.33800000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>17439108.07000000</valUSD>
        <pctVal>1.936447744562</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>STIV</assetCat>
        <issuerCat>RF</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <cashCollateralCondition cashCollateralVal="17439108.07000000" isCashCollateral="Y"/>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>IMMUNOMEDICS INC</name>
        <lei>5493007ZU7DDO8PSIM59</lei>
        <title>IMMUNOMEDICS INC</title>
        <cusip>452907108</cusip>
        <identifiers>
          <isin value="US4529071080"/>
        </identifiers>
        <balance>123400.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>5498704.00000000</valUSD>
        <pctVal>0.610578988103</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>GALAPAGOS GENOMICS NV</name>
        <lei>549300QKJ78IY0IOV655</lei>
        <title>GALAPAGOS GENOMICS NV SPON AR</title>
        <cusip>36315X101</cusip>
        <identifiers>
          <isin value="US36315X1019"/>
        </identifiers>
        <balance>36900.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>4913604.00000000</valUSD>
        <pctVal>0.545609175955</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>BE</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>AKESO INC</name>
        <lei>254900ECWYGR3QW5GF30</lei>
        <title>AKESO INC(180 DAY LOCK UP)</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="FJG793000"/>
        </identifiers>
        <balance>1805000.00000000</balance>
        <units>NS</units>
        <currencyConditional curCd="HKD" exchangeRt="7.75020000"/>
        <valUSD>6538007.08000000</valUSD>
        <pctVal>0.725983749465</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>KY</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>UNIQURE N.V.</name>
        <lei>N/A</lei>
        <title>UNIQURE N.V.</title>
        <cusip>N/A</cusip>
        <identifiers>
          <isin value="NL0010696654"/>
        </identifiers>
        <balance>65600.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>2674512.00000000</valUSD>
        <pctVal>0.296979221036</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>NL</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ROYALTY PHARMA PLC</name>
        <lei>549300FGFN7VOK8BZR03</lei>
        <title>ROYALTY PHARMA PLC</title>
        <cusip>N/A</cusip>
        <identifiers>
          <isin value="GB00BMVP7Y09"/>
        </identifiers>
        <balance>14900.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>616562.00000000</valUSD>
        <pctVal>0.068463369198</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>GB</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>AXSOME THERAPEUTICS INC</name>
        <lei>549300EXGR0XLRJEIB95</lei>
        <title>AXSOME THERAPEUTICS INC</title>
        <cusip>05464T104</cusip>
        <identifiers>
          <isin value="US05464T1043"/>
        </identifiers>
        <balance>43400.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>3181654.00000000</valUSD>
        <pctVal>0.353292535807</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>TRANSLATE BIO INC</name>
        <lei>N/A</lei>
        <title>TRANSLATE BIO INC</title>
        <cusip>89374L104</cusip>
        <identifiers>
          <isin value="US89374L1044"/>
        </identifiers>
        <balance>102900.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1449861.00000000</valUSD>
        <pctVal>0.160993329022</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <loanByFundCondition isLoanByFund="Y" loanVal="1448452.00000000"/>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>MYOKARDIA INC</name>
        <lei>549300OLNNNZ1NI9UY54</lei>
        <title>MYOKARDIA INC</title>
        <cusip>62857M105</cusip>
        <identifiers>
          <isin value="US62857M1053"/>
        </identifiers>
        <balance>16465.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1801929.60000000</valUSD>
        <pctVal>0.200087211787</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
    </invstOrSecs>
    <signature>
      <ncom:dateSigned>2020-09-30</ncom:dateSigned>
      <ncom:nameOfApplicant>Stacie M. Smith</ncom:nameOfApplicant>
      <ncom:signature>Stacie M. Smith</ncom:signature>
      <ncom:signerName>Stacie M. Smith</ncom:signerName>
      <ncom:title>President and Treasurer</ncom:title>
    </signature>
  </formData>
</edgarSubmission>
