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      <invstOrSec>
        <name>GLOBAL BLOOD THERAPEUTICS INC</name>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>TAKEDA PHARMACEUTICAL CO LTD</name>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>NOVARTIS AG</name>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>BOSTON SCIENTIFIC CORP</name>
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        <assetCat>EC</assetCat>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>BAUSCH HEALTH COS INC</name>
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        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>AXSOME THERAPEUTICS INC</name>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>MODERNA INC</name>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>BRISTOL-MYERS SQUIBB CO</name>
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        <fairValLevel>1</fairValLevel>
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        <name>PTC THERAPEUTICS INC</name>
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      <invstOrSec>
        <name>AMGEN INC</name>
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      <invstOrSec>
        <name>HARMONY BIOSCIENCES II INC</name>
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        <name>NEKTAR THERAPEUTICS</name>
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        <name>GALAPAGOS GENOMICS NV</name>
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        <name>REATA PHARMACEUTICALS INC</name>
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        <name>ROCHE HOLDING LTD</name>
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        <name>ATHENEX INC</name>
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        <name>SANOFI</name>
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        <name>MOMENTA PHARMACEUTICALS INC</name>
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        <name>UNIQURE N.V.</name>
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        <name>10X GENOMICS INC</name>
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        <name>ARGENX SE</name>
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        <title>ARGENX SE SPONSORED ADR</title>
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        <name>UCB SA</name>
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        <name>MYOKARDIA INC</name>
        <lei>549300OLNNNZ1NI9UY54</lei>
        <title>MYOKARDIA INC</title>
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          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ZOGENIX INC</name>
        <lei>54930089H3HF4C32SK78</lei>
        <title>ZOGENIX INC</title>
        <cusip>98978L204</cusip>
        <identifiers>
          <isin value="US98978L2043"/>
        </identifiers>
        <balance>31800.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>797544.00000000</valUSD>
        <pctVal>0.104052950170</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>JOHNSON and JOHNSON</name>
        <lei>549300G0CFPGEF6X2043</lei>
        <title>JOHNSON and JOHNSON</title>
        <cusip>478160104</cusip>
        <identifiers>
          <isin value="US4781601046"/>
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        <balance>494450.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>66493636.00000000</valUSD>
        <pctVal>8.675206626019</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>CRONOS GROUP INC</name>
        <lei>N/A</lei>
        <title>CRONOS GROUP INC</title>
        <cusip>22717L101</cusip>
        <identifiers>
          <isin value="CA22717L1013"/>
        </identifiers>
        <balance>273500.00000000</balance>
        <units>NS</units>
        <currencyConditional curCd="CAD" exchangeRt="1.34225000"/>
        <valUSD>1587308.62000000</valUSD>
        <pctVal>0.207090950143</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>CA</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <loanByFundCondition isLoanByFund="Y" loanVal="1422483.92000000"/>
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      </invstOrSec>
      <invstOrSec>
        <name>MERCK and CO INC NEW</name>
        <lei>4YV9Y5M8S0BRK1RP0397</lei>
        <title>MERCK and CO INC NEW</title>
        <cusip>58933Y105</cusip>
        <identifiers>
          <isin value="US58933Y1055"/>
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        <balance>498236.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>38144948.16000000</valUSD>
        <pctVal>4.976646291786</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ARVINAS HOLDING CO LLC</name>
        <lei>N/A</lei>
        <title>ARVINAS HOLDING CO LLC</title>
        <cusip>04335A105</cusip>
        <identifiers>
          <isin value="US04335A1051"/>
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        <balance>98000.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>4618740.00000000</valUSD>
        <pctVal>0.602591860849</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ELANCO ANIMAL HEALTH INC</name>
        <lei>549300SHPNDCE059M934</lei>
        <title>ELANCO ANIMAL HEALTH INC</title>
        <cusip>28414H103</cusip>
        <identifiers>
          <isin value="US28414H1032"/>
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        <balance>235400.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>6449960.00000000</valUSD>
        <pctVal>0.841505128845</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>NOVO-NORDISK AS</name>
        <lei>549300DAQ1CVT6CXN342</lei>
        <title>NOVO-NORDISK AS CL B ADR</title>
        <cusip>670100205</cusip>
        <identifiers>
          <isin value="US6701002056"/>
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        <balance>78200.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>4545766.00000000</valUSD>
        <pctVal>0.593071182384</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>DK</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>ARGENX SE</name>
        <lei>7245009C5FZE6G9ODQ71</lei>
        <title>ARGENX SE</title>
        <cusip>N/A</cusip>
        <identifiers>
          <isin value="NL0010832176"/>
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        <balance>25200.00000000</balance>
        <units>NS</units>
        <currencyConditional curCd="EUR" exchangeRt="0.90583813"/>
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        <pctVal>0.460833788382</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>NL</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>ALCON INC</name>
        <lei>549300LDT5AP8S0NBM78</lei>
        <title>ALCON INC</title>
        <cusip>N/A</cusip>
        <identifiers>
          <isin value="CH0432492467"/>
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        <balance>56169.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>3443159.70000000</valUSD>
        <pctVal>0.449217754370</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>CH</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>ASTELLAS PHARMA INC</name>
        <lei>529900IB708DY2HBBB35</lei>
        <title>ASTELLAS PHARMA INC</title>
        <cusip>N/A</cusip>
        <identifiers>
          <isin value="JP3942400007"/>
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        <balance>710800.00000000</balance>
        <units>NS</units>
        <currencyConditional curCd="JPY" exchangeRt="107.86000000"/>
        <valUSD>11196450.95000000</valUSD>
        <pctVal>1.460764237187</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>JP</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>VERTEX PHARMACEUTICALS INC</name>
        <lei>54930015RAQRRZ5ZGJ91</lei>
        <title>VERTEX PHARMACEUTICALS INC</title>
        <cusip>92532F100</cusip>
        <identifiers>
          <isin value="US92532F1003"/>
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        <balance>43900.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>9834917.00000000</valUSD>
        <pctVal>1.283129367820</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>HORIZON THERAPEUTICS PLC</name>
        <lei>N/A</lei>
        <title>HORIZON THERAPEUTICS PLC</title>
        <cusip>N/A</cusip>
        <identifiers>
          <isin value="IE00BQPVQZ61"/>
        </identifiers>
        <balance>372400.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>12743528.00000000</valUSD>
        <pctVal>1.662606306330</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>IE</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
        </securityLending>
      </invstOrSec>
      <invstOrSec>
        <name>FIDELITY REVERE STREET TRUST</name>
        <lei>549300BDV45LJNXBZC55</lei>
        <title>Fidelity Securities Lending Cash Central Fund</title>
        <cusip>31635A303</cusip>
        <identifiers>
          <isin value="US31635A3032"/>
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        <balance>32422241.43800000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>32425483.66000000</valUSD>
        <pctVal>4.230446515199</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>STIV</assetCat>
        <issuerCat>RF</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <cashCollateralCondition cashCollateralVal="32425483.66000000" isCashCollateral="Y"/>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>BLUEPRINT MEDICINES CORP</name>
        <lei>5299004CC60O9T5HVM83</lei>
        <title>BLUEPRINT MEDICINES CORP</title>
        <cusip>09627Y109</cusip>
        <identifiers>
          <isin value="US09627Y1091"/>
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        <balance>34700.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1878311.00000000</valUSD>
        <pctVal>0.245057076333</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>FIDELITY REVERE STREET TRUST</name>
        <lei>549300BDV45LJNXBZC55</lei>
        <title>Fidelity Cash Central Fund</title>
        <cusip>31635A105</cusip>
        <identifiers>
          <isin value="US31635A1051"/>
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        <balance>8262235.61000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>8263888.06000000</valUSD>
        <pctVal>1.078162374137</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>STIV</assetCat>
        <issuerCat>RF</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>GLAXOSMITHKLINE PLC</name>
        <lei>5493000HZTVUYLO1D793</lei>
        <title>GLAXOSMITHKLINE PLC SPONS ADR</title>
        <cusip>37733W105</cusip>
        <identifiers>
          <isin value="US37733W1053"/>
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        <balance>289000.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>11713170.00000000</valUSD>
        <pctVal>1.528178877083</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>GB</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      <invstOrSec>
        <name>THERAVANCE BIOPHARMA INC</name>
        <lei>5493007VTSXP4Z6MIW52</lei>
        <title>THERAVANCE BIOPHARMA INC</title>
        <cusip>N/A</cusip>
        <identifiers>
          <isin value="KYG8807B1068"/>
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        <balance>35597.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>866786.95000000</valUSD>
        <pctVal>0.113086850777</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>KY</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>ALLERGAN PLC</name>
        <lei>635400FWJZQC1IPYUH69</lei>
        <title>ALLERGAN PLC</title>
        <cusip>N/A</cusip>
        <identifiers>
          <isin value="IE00BY9D5467"/>
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        <balance>93038.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>17739555.46000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>IE</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>RICHTER GEDEON PLC</name>
        <lei>549300J6ZJW5IH4WEE46</lei>
        <title>RICHTER GEDEON VEGYESZETI NY</title>
        <cusip>N/A</cusip>
        <identifiers>
          <isin value="HU0000123096"/>
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        <balance>157700.00000000</balance>
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        <currencyConditional curCd="HUF" exchangeRt="306.31380000"/>
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        <pctVal>0.417451483717</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>HU</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>GENERATION BIO</name>
        <lei>N/A</lei>
        <title>GENERATION BIO CO SER C PC PP</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="FFB638000"/>
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        <balance>13200.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>73806.48000000</valUSD>
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        <payoffProfile>Long</payoffProfile>
        <assetCat>EP</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>3</fairValLevel>
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          <isCashCollateral>N</isCashCollateral>
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      <invstOrSec>
        <name>LEAP THERAPEUTICS INC</name>
        <lei>549300T31SMMJ2DDLI13</lei>
        <title>LEAP THERAPEUTICS INC</title>
        <cusip>52187K101</cusip>
        <identifiers>
          <isin value="US52187K1016"/>
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        <balance>254900.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>614309.00000000</valUSD>
        <pctVal>0.080146880631</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <loanByFundCondition isLoanByFund="Y" loanVal="548342.48000000"/>
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      <invstOrSec>
        <name>INNOVENT BIOLGICS INC</name>
        <lei>25490058ONL9SCIE1R22</lei>
        <title>INNOVENT BIOLOGICS INC</title>
        <cusip>N/A</cusip>
        <identifiers>
          <isin value="KYG4818G1010"/>
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        <balance>920000.00000000</balance>
        <units>NS</units>
        <currencyConditional curCd="HKD" exchangeRt="7.79500000"/>
        <valUSD>4201667.74000000</valUSD>
        <pctVal>0.548177810856</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>KY</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>PERRIGO CO PLC</name>
        <lei>549300IFOQS6R1QLY196</lei>
        <title>PERRIGO CO PLC</title>
        <cusip>N/A</cusip>
        <identifiers>
          <isin value="IE00BGH1M568"/>
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        <balance>208500.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>10568865.00000000</valUSD>
        <pctVal>1.378885156430</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>IE</invCountry>

        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
          <isNonCashCollateral>N</isNonCashCollateral>
          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>KALVISTA PHARMACEUTICALS INC</name>
        <lei>529900Q7IDA3WUGRZA51</lei>
        <title>KALVISTA PHARMACEUTICALS INC</title>
        <cusip>483497103</cusip>
        <identifiers>
          <isin value="US4834971032"/>
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        <balance>99000.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>1331550.00000000</valUSD>
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        <fairValLevel>1</fairValLevel>
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        <name>OLIVO LABS LLC</name>
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        <name>CASTLE CREEK PHARMACEUTICAL HOLDINGS INC</name>
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        <fairValLevel>3</fairValLevel>
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        <name>ASCENDIS PHARMA A/S</name>
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        <fairValLevel>1</fairValLevel>
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        <fairValLevel>1</fairValLevel>
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        <name>MIRATI THERAPEUTICS INC</name>
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        <fairValLevel>1</fairValLevel>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>LILLY (ELI) and CO</name>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>ZOETIS INC</name>
        <lei>549300HD9Q1LOC9KLJ48</lei>
        <title>ZOETIS INC CL A</title>
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          <isin value="US98978V1035"/>
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        <balance>264900.00000000</balance>
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        <curCd>USD</curCd>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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        <name>MAGENTA THERAPEUTICS INC</name>
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        <invCountry>US</invCountry>
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        <fairValLevel>1</fairValLevel>
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      <invstOrSec>
        <name>ASTRAZENECA PLC</name>
        <lei>PY6ZZQWO2IZFZC3IOL08</lei>
        <title>ASTRAZENECA PLC SPONS ADR</title>
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        <assetCat>EC</assetCat>
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        <invCountry>GB</invCountry>
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        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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          <isLoanByFund>N</isLoanByFund>
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      </invstOrSec>
      <invstOrSec>
        <name>MYOS RENS TECHNOLOGY INC</name>
        <lei>549300ZNQGSJ2V3ZB668</lei>
        <title>MYOS CORP PIPE</title>
        <cusip>N/A</cusip>
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          <other otherDesc="Internal" value="554051920"/>
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        <balance>40000.00000000</balance>
        <units>NS</units>
        <curCd>USD</curCd>
        <valUSD>46800.00000000</valUSD>
        <pctVal>0.006105842521</pctVal>
        <payoffProfile>Long</payoffProfile>
        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>Y</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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      </invstOrSec>
      <invstOrSec>
        <name>SAREPTA THERAPEUTICS INC</name>
        <lei>549300IKDPIED8J8IG21</lei>
        <title>SAREPTA THERAPEUTICS INC</title>
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        <valUSD>6208967.27000000</valUSD>
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        <assetCat>EC</assetCat>
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        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>1</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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      </invstOrSec>
      <invstOrSec>
        <name>LEAP THERAPEUTICS INC</name>
        <lei>549300T31SMMJ2DDLI13</lei>
        <title>LEAP THERAPEUTICS INC WT</title>
        <cusip>N/A</cusip>
        <identifiers>
          <other otherDesc="Internal" value="EBC951000"/>
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        <balance>606000.00000000</balance>
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        <curCd>USD</curCd>
        <valUSD>776098.14000000</valUSD>
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        <assetCat>EC</assetCat>
        <issuerCat>CORP</issuerCat>
        <invCountry>US</invCountry>
        <isRestrictedSec>N</isRestrictedSec>

        <fairValLevel>2</fairValLevel>
        <securityLending>
          <isCashCollateral>N</isCashCollateral>
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        </securityLending>
      </invstOrSec>
    </invstOrSecs>
    <signature>
      <ncom:dateSigned>2020-03-30</ncom:dateSigned>
      <ncom:nameOfApplicant>Stacie M. Smith</ncom:nameOfApplicant>
      <ncom:signature>Stacie M. Smith</ncom:signature>
      <ncom:signerName>Stacie M. Smith</ncom:signerName>
      <ncom:title>President and Treasurer</ncom:title>
    </signature>
  </formData>
</edgarSubmission>
