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Description of Business and Basis of Presentation (Anti-dilutive Shares) (Details) - shares
shares in Thousands
9 Months Ended
Sep. 30, 2018
Sep. 30, 2017
Schedule of anti-dilutive shares excluded from computation of net loss per share    
Anti-dilutive, shares 11,199 9,831
Outstanding options to purchase common stock    
Schedule of anti-dilutive shares excluded from computation of net loss per share    
Anti-dilutive, shares 357 364
Unvested restricted stock awards    
Schedule of anti-dilutive shares excluded from computation of net loss per share    
Anti-dilutive, shares 0 29
Unvested restricted stock unit awards    
Schedule of anti-dilutive shares excluded from computation of net loss per share    
Anti-dilutive, shares 3,016 2,760
Employee stock purchase plan awards    
Schedule of anti-dilutive shares excluded from computation of net loss per share    
Anti-dilutive, shares 77 29
Bonus and director fees to be paid in stock awards    
Schedule of anti-dilutive shares excluded from computation of net loss per share    
Anti-dilutive, shares 504 349
Convertible senior notes    
Schedule of anti-dilutive shares excluded from computation of net loss per share    
Anti-dilutive, shares 7,245 6,300