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Description of Business and Basis of Presentation (Anti-dilutive Shares) (Details) - shares
shares in Thousands
6 Months Ended
Jun. 30, 2018
Jun. 30, 2017
Schedule of anti-dilutive shares excluded from computation of net loss per share    
Anti-dilutive, shares 11,248 3,148
Outstanding options to purchase common stock    
Schedule of anti-dilutive shares excluded from computation of net loss per share    
Anti-dilutive, shares 357 393
Unvested restricted stock awards    
Schedule of anti-dilutive shares excluded from computation of net loss per share    
Anti-dilutive, shares 0 30
Unvested restricted stock unit awards    
Schedule of anti-dilutive shares excluded from computation of net loss per share    
Anti-dilutive, shares 3,294 2,499
Employee stock purchase plan awards    
Schedule of anti-dilutive shares excluded from computation of net loss per share    
Anti-dilutive, shares 50 0
Bonus and director fees to be paid in stock awards    
Schedule of anti-dilutive shares excluded from computation of net loss per share    
Anti-dilutive, shares 302 226
Convertible senior notes    
Schedule of anti-dilutive shares excluded from computation of net loss per share    
Anti-dilutive, shares 7,245 0