EX-99

                                                                    Exhibit 99.1



                            Explanation of Responses


(1) Mr. Larry N. Feinberg ("Mr. Feinberg") serves as: (i) managing member of
Oracle Associates, LLC ("Oracle Associates"), which is general partner of Oracle
Partners, L.P. ("Oracle Partners"), Oracle Institutional, L.P. ("Oracle
Institutional") and certain other investment funds and accounts (collectively,
the "Domestic Funds"); (ii) sole shareholder and president of Oracle Investment
Management, Inc., a Delaware corporation ("Oracle Investment Management"), which
serves as investment manager to and has investment discretion over the
securities held by (a) SAM Oracle Investments Inc. ("SAM Oracle"), (b) Oracle
Offshore Limited, a Cayman Islands corporation (together with SAM Oracle a
certain other funds, the "Foreign Funds") and (c) Oracle Management, Inc.
Employees Retirement Plan, ("Oracle 401K" together with the Foreign Funds, the
"Managed Funds" and, together with the Domestic Funds, the "Funds") and (iii)
trustee of The Feinberg Family Foundation (the "Foundation"). The shares of
common stock, par value $0.01 per share (the "Common Stock"), of Access
Pharmaceuticals, Inc. (the "Company"), Series A Cumulative Convertible Preferred
Stock, par value $0.01 per share (the "Preferred Stock"), of the Company and the
Common Stock Purchase Warrants (the "Warrants") to which this Form 4 pertains
are held directly by the Funds and the Foundation, which Mr. Feinberg may be
deemed to beneficially own by virtue of the foregoing relationships. In
accordance with instruction 4(b)(v), the entire number of shares of Common
Stock, Preferred Stock and Warrants that may be deemed to be beneficially owned
by Mr. Feinberg by virtue of such relationships is reported herein. Mr. Feinberg
disclaims any beneficial ownership of the securities held by the Funds and the
Foundation for purposes of Section 16 of the Securities Exchange Act of 1934,
except to the extent of Mr. Feinberg's pecuniary interest.

(2) As of the date hereof, Mr. Feinberg beneficially owns 2,483,040 shares,
consisting of 296,483 shares of Common Stock (3,660 shares of which are held
directly by the Foundation), 1,457,707 shares of Common Stock that would be
received upon the conversion of 437 shares of Preferred Stock, and 728,850
shares of that would be received on exercise of the Warrants.

(3) Mr. Feinberg serves as trustee of Foundation which holds 3,660 shares of
Common Stock directly. Mr. Feinberg may be deemed to beneficially own such
shares by virtue of his position as trustee and such shares are included in Mr.
Feinberg's total beneficial ownership indicated in note (2) above.

(4) On June 6, 2005, the Company effected a five-to-one reverse stock split of
its Common Stock. The disposition of shares to which this note relates does not
represent a sale of beneficial ownership. It represents solely an adjustment due
to such stock split.

(5) This transaction involved an administrative adjustment for accounting
purposes only.

(6) Each share of Preferred Stock is convertible in whole or in part, at any
time or from time to time, at the option of the holder into 3,333.33 shares of
Common Stock, at an exercise price of $3.00, subject to adjustment.

(7) A series of transactions involving the Company were described in the
Company's Current Report on Form 8-K, filed on November 14, 2007. In connection
with these transactions, existing convertible notes held by the Funds having an
aggregate value of $4,373,104.54 (principal amount of $4,015,000 plus interest
accrued thereon of $358,104.54), were exchanged into 437 shares of Preferred
Stock and Warrants to purchase 728,850 shares of Common Stock.

(8) The transactions to which this note relates involve a transfer of Preferred
Stock and Warrants held by SAM Oracle to Oracle Institutional in connection with
the liquidation of the portfolio of SAM Oracle. The transferred Preferred Stock
was at such time valued at $495,720 and no value was accorded to the transferred
Warrants.

(9) The Warrants are exercisable in whole or in part, at any time or from time
to time (beginning on November 10, 2007), at the option of the holder until
November 10, 2013, at an exercise price of $3.50 per share, subject to
adjustment.





(10) Oracle Associates is general partner of the Domestic Funds. The shares of
Common Stock, Preferred Stock and Warrants to which this note pertains are held
directly by the Domestic Funds, which Oracle Associates may be deemed to
beneficially own by virtue of the foregoing relationship. In accordance with
instruction 4(b)(v), the entire number of shares of Common Stock, Preferred
Stock and Warrants that may be deemed to be beneficially owned by Oracle
Associates by virtue of such relationships is reported herein. Oracle Associates
disclaims any beneficial ownership of the securities held by the Domestic Funds
for purposes of Section 16 of the Securities Exchange Act of 1934, except to the
extent of Oracle Associates' pecuniary interest.

(11) As of the date hereof, Oracle Associates beneficially owns 2,402,486
shares, consisting of 287,816 shares of Common Stock, 1,409,782 shares of Common
Stock that would be received upon the conversion of 423 shares of Preferred
Stock, and 704,888 shares that would be received upon the exercise of Warrants.

(12) As of the date hereof, Oracle Partners beneficially owns 1,622,488 shares,
consisting of 247,651 shares of Common Stock, 916,560 shares of Common Stock
that would be received upon the conversion of 275 shares of Preferred Stock and
458,277 shares that would be received upon exercise of Warrants.

(13) Oracle Investment Management ("Investment Manager") serves as investment
manager to and has investment discretion over the securities held by the Managed
Funds. The shares of Common Stock, Preferred Stock and Warrants to which this
note pertains are held directly by the Managed Funds, which the Investment
Manager may be deemed to beneficially own by virtue of the foregoing
relationship. In accordance with instruction 4(b)(v), the entire number of
shares of Common Stock, Preferred Stock and Warrants that may be deemed to be
beneficially owned by the Investment Manager by virtue of such relationship is
reported herein. The Investment Manager disclaims any beneficial ownership of
the securities held by the Managed Funds for purposes of Section 16 of the
Securities Exchange Act of 1934, except to the extent of the Investment
Manager's pecuniary interest.

(14) As of the date hereof, Oracle Investment Management beneficially owns
76,893 shares consisting of 5007 shares of Common Stock, 47,924 shares of Common
Stock that would be received upon the conversion of 14 shares of Preferred Stock
and 23,962 shares that would be received upon exercise of Warrants.

(15) As of the date hereof, Oracle Institutional beneficially owns 779,998
shares consisting of 40,165 shares of Common Stock, 493,222 shares of Common
Stock that would be received upon the conversion of 148 shares of Preferred
Stock and 246,611 shares that would be received upon exercise of Warrants.

EX-99

                                                                    Exhibit 99.2
                         FORM 4 JOINT FILER INFORMATION

          (Attachment to Form 4 in accordance with instruction 4(b)(v))

Check this box if no longer subject to
  Section 16:                             [ ]

Name and Address:                         Oracle Associates, LLC
                                          200 Greenwich Avenue, 3rd Floor
                                          Greenwich, CT 06830

Issuer and Ticker Symbol:                 Access Pharmaceuticals, Inc. ("ACCP")

Date of Earliest Transaction:             12/31/05

Relationship to Issuer:                   10% Owner

Designated Filer:                         Larry N. Feinberg

TABLE I INFORMATION
Title of Security:                        Common Stock
Transaction Date:                         12/31/2005
Transaction Code:                         P
Securities Disposed:                      299,056
Acquired or Disposed:                     A
Price:                                    $0.65
Ownership Form:                           I
Amount Beneficially Owned After
  Transaction                             (11)
Nature of Indirect Beneficial
  Ownership                               (10)

Title of Security:                        Common Stock
Transaction Date:                         12/31/2005
Transaction Code:                         P
Securities Disposed:                      82,745
Acquired or Disposed:                     A
Price:                                    $0.65
Ownership Form:                           I
Amount Beneficially Owned After
  Transaction                             (11)
Nature of Indirect Beneficial
  Ownership                               (10)

Title of Security:                        Common Stock
Transaction Date:                         6/5/2006
Transaction Code:                         (J) (4)
Securities Disposed:                      14,104,032
Acquired or Disposed:                     D
Price:                                    $0.00
Ownership Form:                           I
Amount Beneficially Owned After
  Transaction                             (11)
Nature of Indirect Beneficial
  Ownership                               (10)





Title of Security:                        Common Stock
Transaction Date:                         6/5/2006
Transaction Code:                         (J) (4)
Securities Disposed:                      222,116
Acquired or Disposed:                     D
Price:                                    $0.00
Ownership Form:                           I
Amount Beneficially Owned After
  Transaction                             (11)
Nature of Indirect Beneficial
  Ownership                               (10)

Title of Security:                        Common Stock
Transaction Date:                         9/1/2006
Transaction Code:                         J
Securities Disposed:                      0.2
Acquired or Disposed:                     D
Price:                                    $0.00 (5)
Ownership Form:                           I
Amount Beneficially Owned After
  Transaction                             (11)
Nature of Indirect Beneficial
  Ownership                               (10)

Title of Security:                        Common Stock
Transaction Date:                         1/22/2007
Transaction Code:                         P
Securities Disposed:                      6,040
Acquired or Disposed:                     A
Price:                                    $2.53
Ownership Form:                           I
Amount Beneficially Owned After
  Transaction                             (11)
Nature of Indirect Beneficial
  Ownership                               (10)

Title of Security:                        Common Stock
Transaction Date:                         2/26/2007
Transaction Code:                         S
Securities Disposed:                      19,000
Acquired or Disposed:                     D
Price:                                    $7.314
Ownership Form:                           I
Amount Beneficially Owned After
  Transaction                             (11)
Nature of Indirect Beneficial
  Ownership                               (10)

Title of Security:                        Common Stock
Transaction Date:                         2/26/2007
Transaction Code:                         S
Securities Disposed:                      5,000
Acquired or Disposed:                     D
Price:                                    $7.314
Ownership Form:                           I
Amount Beneficially Owned After
  Transaction                             (11)
Nature of Indirect Beneficial
  Ownership                               (10)





Title of Security:                        Common Stock
Transaction Date:                         2/27/2007
Transaction Code:                         S
Securities Disposed:                      300
Acquired or Disposed:                     D
Price:                                    $7.00
Ownership Form:                           I
Amount Beneficially Owned After
  Transaction                             (11)
Nature of Indirect Beneficial
  Ownership                               (10)

Title of Security:                        Common Stock
Transaction Date:                         2/27/2007
Transaction Code:                         S
Securities Disposed:                      100
Acquired or Disposed:                     D
Price:                                    $7.00
Ownership Form:                           I
Amount Beneficially Owned After
  Transaction                             (11)
Nature of Indirect Beneficial
  Ownership                               (10)

Title of Security:                        Common Stock
Transaction Date:                         6/19/2007
Transaction Code:                         S
Securities Disposed:                      40,000
Acquired or Disposed:                     D
Price:                                    $5.17
Ownership Form:                           I
Amount Beneficially Owned After
  Transaction                             (11)
Nature of Indirect Beneficial
  Ownership                               (10)

Title of Security:                        Common Stock
Transaction Date:                         6/19/2007
Transaction Code:                         P
Securities Disposed:                      60,000
Acquired or Disposed:                     A
Price:                                    $5.17
Ownership Form:                           I
Amount Beneficially Owned After
  Transaction                             (11)
Nature of Indirect Beneficial
  Ownership                               (10)





Title of Security:                        Common Stock
Transaction Date:                         2/12/2008
Transaction Code:                         P
Securities Disposed:                      29,736
Acquired or Disposed:                     A
Price:                                    $3.15
Ownership Form:                           I
Amount Beneficially Owned After
  Transaction                             (11)
Nature of Indirect Beneficial
  Ownership                               (10)

TABLE II INFORMATION
Title of Derivative Security:             Preferred Stock
Conversion or Exercise Price of
  Derivative Security                     (6)
Transaction Date:                         11/10/07
Transaction Code:                         J (7)
Securities Acquired:                      351
Date Exercisable and Expiration Date:     (6)
Title of Underlying Securities:           Common Stock
Amount of Underlying Securities:          1,170,150
Price of Derivative Securities:           (7)
Number Beneficially Owned                 351
Ownership Form:                           I
Nature of Indirect Beneficial
  Ownership                               (10)

Title of Derivative Security:             Warrants
Conversion or Exercise Price of
  Derivative Security                     (9)
Transaction Date:                         11/10/07
Transaction Code:                         J (7)
Securities Acquired:                      585,077
Date Exercisable and Expiration Date:     (9)
Title of Underlying Securities:           Common Stock
Amount of Underlying Securities:          585,077
Price of Derivative Securities:           (7)
Number Beneficially Owned                 585,077
Ownership Form:                           I
Nature of Indirect Beneficial
  Ownership                               (10)

Title of Derivative Security:             Preferred Stock
Conversion or Exercise Price of
  Derivative Security                     (6)
Transaction Date:                         3/11/08
Transaction Code:                         P
Securities Acquired:                      72
Date Exercisable and Expiration Date:     (6)
Title of Underlying Securities:           Common Stock
Amount of Underlying Securities:          240,000
Price of Derivative Securities:           (8)
Number Beneficially Owned                 423
Ownership Form:                           I
Nature of Indirect Beneficial
  Ownership                               (10)





Title of Derivative Security:             Warrants
Conversion or Exercise Price of
  Derivative Security                     (9)
Transaction Date:                         3/11/08
Transaction Code:                         P
Securities Acquired:                      119,811
Date Exercisable and Expiration Date:     (9)
Title of Underlying Securities:           Common Stock
Amount of Underlying Securities:          119,811
Price of Derivative Securities:           (8)
Number Beneficially Owned                 119,811
Ownership Form:                           I
Nature of Indirect Beneficial
  Ownership                               (10)

Explanation of Responses:

(4) - (11): See Exhibit 99.1.


   Signature:                             ORACLE ASSOCIATES, LLC


                                          By: /s/ Larry N. Feinberg
                                              ----------------------------------
                                              Name:   Larry N. Feinberg
                                              Title:  Managing Member

    Date:                                 June 10, 2008

EX-99

                                                                    Exhibit 99.3
                         FORM 4 JOINT FILER INFORMATION

          (Attachment to Form 4 in accordance with instruction 4(b)(v))


Check this box if no longer subject to
  Section 16:                             [ ]

Name and Address:                         Oracle Partners, L.P.
                                          c/o Oracle Associates, LLC
                                          200 Greenwich Avenue, 3rd Floor
                                          Greenwich, CT 06830

Issuer and Ticker Symbol:                 Access Pharmaceuticals, Inc. ("ACCP")

Date of Earliest Transaction:             12/31/05

Relationship to Issuer:                   10% Owner

Designated Filer:                         Larry N. Feinberg

TABLE I INFORMATION
Title of Security:                        Common Stock
Transaction Date:                         12/31/2005
Transaction Code:                         P
Securities Disposed:                      299,056
Acquired or Disposed:                     A
Price:                                    $0.65
Ownership Form:                           D
Amount Beneficially Owned After
  Transaction                             (12)
Nature of Indirect Beneficial
  Ownership

Title of Security:                        Common Stock
Transaction Date:                         6/5/2006
Transaction Code:                         (J) (4)
Securities Disposed:                      14,104,032
Acquired or Disposed:                     D
Price:                                    $0.00
Ownership Form:                           D
Amount Beneficially Owned After
  Transaction                             (12)
Nature of Indirect Beneficial
  Ownership

Title of Security:                        Common Stock
Transaction Date:                         9/1/2006
Transaction Code:                         S
Securities Disposed:                      0.2 (5)
Acquired or Disposed:                     D
Price:                                    $0.00
Ownership Form:                           D
Amount Beneficially Owned After
  Transaction                             (12)
Nature of Indirect Beneficial
  Ownership





Title of Security:                        Common Stock
Transaction Date:                         1/22/2007
Transaction Code:                         P
Securities Disposed:                      6,040
Acquired or Disposed:                     A
Price:                                    $2.53
Ownership Form:                           D
Amount Beneficially Owned After
  Transaction                             (12)
Nature of Indirect Beneficial
  Ownership

Title of Security:                        Common Stock
Transaction Date:                         2/26/2007
Transaction Code:                         S
Securities Disposed:                      19,000
Acquired or Disposed:                     D
Price:                                    $7.314
Ownership Form:                           D
Amount Beneficially Owned After
  Transaction                             (12)
Nature of Indirect Beneficial
  Ownership

Title of Security:                        Common Stock
Transaction Date:                         2/27/2007
Transaction Code:                         S
Securities Disposed:                      300
Acquired or Disposed:                     D
Price:                                    $7.00
Ownership Form:                           D
Amount Beneficially Owned After
  Transaction                             (12)
Nature of Indirect Beneficial
  Ownership

Title of Security:                        Common Stock
Transaction Date:                         6/19/2007
Transaction Code:                         P
Securities Disposed:                      60,000
Acquired or Disposed:                     A
Price:                                    $5.17
Ownership Form:                           D
Amount Beneficially Owned After
  Transaction                             (12)
Nature of Indirect Beneficial
  Ownership

TABLE II INFORMATION
Title of Derivative Security:             Preferred Stock
Conversion or Exercise Price of
  Derivative Security                     (6)
Transaction Date:                         11/10/07
Transaction Code:                         J (7)
Securities Acquired:                      275
Date Exercisable and Expiration Date:     (6)
Title of Underlying Securities:           Common Stock
Amount of Underlying Securities:          916,552
Price of Derivative Securities:           (7)
Number Beneficially Owned                 275
Ownership Form:                           D





Title of Derivative Security:             Warrants
Conversion or Exercise Price of
  Derivative Security                     (6)
Transaction Date:                         11/10/07
Transaction Code:                         J (7)
Securities Acquired:                      458,277
Date Exercisable and Expiration Date:     (9)
Title of Underlying Securities:           Common Stock
Amount of Underlying Securities:          458,277
Price of Derivative Securities:           (7)
Number Beneficially Owned                 458,277
Ownership Form:                           D


Explanation of Responses:

(4) - (7), (9) and (12): See Exhibit
  99.1.


   Signature:                             ORACLE PARTNERS, L.P.

                                          By: Oracle Associates, LLC,
                                              its General Partner

                                          By:  /s/ Larry N. Feinberg
                                               ---------------------------------
                                               Name:   Larry N. Feinberg
                                               Title:  Managing Member

    Date:                                 June 10, 2008

EX-99

                                                                    Exhibit 99.4
                         FORM 4 JOINT FILER INFORMATION

          (Attachment to Form 4 in accordance with instruction 4(b)(v))


Check this box if no longer subject to
  Section 16:                             [ ]

Name and Address:                         Oracle Institutional Partners, L.P.
                                          c/o Oracle Associates, LLC
                                          200 Greenwich Avenue, 3rd Floor
                                          Greenwich, CT 06830

Issuer and Ticker Symbol:                 Access Pharmaceuticals, Inc. ("ACCP")

Date of Earliest Transaction:             12/31/2005

Relationship to Issuer:                   10% Owner

Designated Filer:                         Larry N. Feinberg

TABLE I INFORMATION
Title of Security:                        Common Stock
Transaction Date:                         12/31/2005
Transaction Code:                         P
Securities Disposed:                      82,745
Acquired or Disposed:                     A
Price:                                    $0.65
Ownership Form:                           D
Amount Beneficially Owned After
  Transaction                             (15)
Nature of Indirect Beneficial
  Ownership

Title of Security:                        Common Stock
Transaction Date:                         6/5/2006
Transaction Code:                         (J) (4)
Securities Disposed:                      222,116
Acquired or Disposed:                     D
Price:                                    $0.00
Ownership Form:                           D
Amount Beneficially Owned After
  Transaction                             (15)
Nature of Indirect Beneficial
  Ownership

Title of Security:                        Common Stock
Transaction Date:                         2/26/2007
Transaction Code:                         S
Securities Disposed:                      5,000
Acquired or Disposed:                     D
Price:                                    $7.314
Ownership Form:                           D
Amount Beneficially Owned After
  Transaction                             (15)
Nature of Indirect Beneficial
  Ownership





Title of Security:                        Common Stock
Transaction Date:                         2/27/2007
Transaction Code:                         S
Securities Disposed:                      100
Acquired or Disposed:                     D
Price:                                    $7.00
Ownership Form:                           D
Amount Beneficially Owned After
  Transaction                             (15)
Nature of Indirect Beneficial
  Ownership

Title of Security:                        Common Stock
Transaction Date:                         6/19/2007
Transaction Code:                         P
Securities Disposed:                      40,000
Acquired or Disposed:                     A
Price:                                    $5.17
Ownership Form:                           D
Amount Beneficially Owned After
  Transaction                             (15)
Nature of Indirect Beneficial
  Ownership

Title of Security:                        Common Stock
Transaction Date:                         2/12/2008
Transaction Code:                         P
Securities Disposed:                      29,736
Acquired or Disposed:                     A
Price:                                    $3.15
Ownership Form:                           D
Amount Beneficially Owned After
  Transaction                             (15)
Nature of Indirect Beneficial
  Ownership

TABLE II INFORMATION
Title of Derivative Security:             Preferred Stock
Conversion or Exercise Price of
  Derivative Security                     (6)
Transaction Date:                         11/10/07
Transaction Code:                         J
Securities Acquired:                      76
Date Exercisable and Expiration Date:     (6)
Title of Underlying Securities:           Common Stock
Amount of Underlying Securities:          253,600
Price of Derivative Securities:           (7)
Number Beneficially Owned                 76
Ownership Form:                           D

Title of Derivative Security:             Warrants
Conversion or Exercise Price of
  Derivative Security                     (9)
Transaction Date:                         11/10/07
Transaction Code:                         P
Securities Acquired:                      126,800
Date Exercisable and Expiration Date:     (9)
Title of Underlying Securities:           Common Stock
Amount of Underlying Securities:          126,800
Price of Derivative Securities:           (7)
Number Beneficially Owned                 126,800
Ownership Form:                           D
Nature of Indirect Beneficial
  Ownership





Title of Derivative Security:             Preferred Stock
Conversion or Exercise Price of
  Derivative Security                     (6)
Transaction Date:                         3/11/08 (7)
Transaction Code:                         P
Securities Acquired:                      72
Date Exercisable and Expiration Date:     (6)
Title of Underlying Securities:           Common Stock
Amount of Underlying Securities:          240,000
Price of Derivative Securities:           (8)
Number Beneficially Owned                 148
Ownership Form:                           D
Nature of Indirect Beneficial
  Ownership

Title of Derivative Security:             Warrants
Conversion or Exercise Price of
  Derivative Security                     (9)
Transaction Date:                         3/11/08 (7)
Transaction Code:                         P
Securities Acquired:                      119,811
Date Exercisable and Expiration Date:     (9)
Title of Underlying Securities:           Common Stock
Amount of Underlying Securities:          119,811
Price of Derivative Securities:           (8)
Number Beneficially Owned                 246,611
Ownership Form:                           D
Nature of Indirect Beneficial
  Ownership



Explanation of Responses:

(4), (6) - (9), (12), and (15) See Exhibit
  99.1.


   Signature:                             ORACLE INSTITUTIONAL PARTNERS, L.P.

                                          By: Oracle Associates, LLC,
                                              its General Partner

                                          By:  /s/ Larry N. Feinberg
                                               ---------------------------------
                                               Name:   Larry N. Feinberg
                                               Title:   Managing Member

    Date:                                 June 10, 2008

EX-99

                                                                    Exhibit 99.5

                         FORM 4 JOINT FILER INFORMATION

          (Attachment to Form 4 in accordance with instruction 4(b)(v))

Check this box if no longer subject to
  Section 16:                             [ X ]

Name and Address:                         Oracle Investment Management, Inc.
                                          200 Greenwich Avenue, 3rd Floor
                                          Greenwich, CT 06830

Issuer and Ticker Symbol:                 Access Pharmaceuticals, Inc. ("ACCP")

Date of Earliest Transaction:             2/12/08

Relationship to Issuer:                   10% Owner

Designated Filer:                         Larry N. Feinberg

TABLE I INFORMATION
Title of Security:                        Common Stock
Transaction Date:                         2/12/2008
Transaction Code:                         S
Securities Disposed:                      29,736
Acquired or Disposed:                     D
Price:                                    $3.15
Ownership Form:                           I
Amount Beneficially Owned After
  Transaction                             (14)
Nature of Indirect Beneficial
  Ownership                               (13)

TABLE II INFORMATION
Title of Derivative Security:             Preferred Stock
Conversion or Exercise Price of
  Derivative Security                     (6)
Transaction Date:                         11/10/2007
Transaction Code:                         S (7)
Securities Acquired:                      86
Date Exercisable and Expiration Date:     (6)
Title of Underlying Securities:           Common Stock
Amount of Underlying Securities:          240,000
Price of Derivative Securities:           $6,885.00
Number Beneficially Owned                 86
Ownership Form:                           I
Nature of Indirect Beneficial
  Ownership                               (13)





Title of Derivative Security:             Warrants
Conversion or Exercise Price of
  Derivative Security                     (9)
Transaction Date:                         11/10/2007
Transaction Code:                         S
Securities Acquired:                      143,773
Date Exercisable and Expiration Date:     (9)
Title of Underlying Securities:           Common Stock
Amount of Underlying Securities:          143,773
Price of Derivative Securities:           (7)
Number Beneficially Owned                 143,773
Ownership Form:                           I
Nature of Indirect Beneficial
  Ownership                               (13)

Explanation of Responses:

(6), (7), (9), (13) and (14):  See
  Exhibit 99.1.


   Signature:                             ORACLE INVESTMENT MANAGEMENT, INC.


                                          By:  /s/ Larry N. Feinberg
                                               ---------------------------------
                                               Name:   Larry N. Feinberg
                                               Title:  President

    Date:                                 June 10, 2008