X0306 4 2022-05-17 0000318154 AMGEN INC AMGN 0001523102 ISHRAK OMAR ONE AMGEN CENTER DRIVE THOUSAND OAKS CA 91320 1 Common Stock 2022-05-17 4 A 0 855 0 A 1930.7414 D The Restricted Stock Units (RSUs) were granted pursuant to the Amgen Inc. 2009 Director Incentive Program, as amended, under the Amgen Inc. 2009 Amended and Restated Equity Incentive Plan and vested immediately. Vested RSUs are paid in shares of the Company's common stock on a one-to-one basis. Vested RSUs may be deferred by the director, in which case payment will occur according to the elected deferral schedule. /s/ S. Omar Ishrak 2022-05-19