X0206 3 2022-03-14 0 0000318154 AMGEN INC AMGN 0001917312 Miller Derek ONE AMGEN CENTER DRIVE THOUSAND OAKS CA 91320 1 SVP, Human Resources Common Stock 5843 D Nqso (Right to Buy) 156.35 2018-05-03 2026-05-03 Common Stock 1524 D Nqso (Right to Buy) 162.60 2019-05-01 2027-05-02 Common Stock 2069 D Nqso (Right to Buy) 177.46 2020-04-27 2028-04-27 Common Stock 1821 D Nqso (Right to Buy) 177.31 2021-05-03 2029-05-03 Common Stock 3692 D Nqso (Right to Buy) 236.36 2022-05-05 2030-05-05 Common Stock 3365 D Nqso (Right to Buy) 239.64 2023-04-30 2031-04-30 Common Stock 3405 D These shares include the following Restricted Stock Units (RSUs) granted under the Amgen Inc. 2009 Equity Incentive Plan: 81 RSUs which will vest on 4/27/2022; 614 RSUs which will vest on 4/27/2022; 283 RSUs which vest in installments of 139 on 5/3/2022 and 144 on 5/3/2023; 401 RSUs which vest in two installments of 132 on 5/5/2022 and 5/5/2023 and one installment of 137 on 5/5/2024; 392 RSUs which vest in two installments of 129 on 4/30/2023 and on 4/30/2024 and 134 on 4/30/2025; and 350 RSUs which vest in two installments of 175 on 11/5/2022 and 11/5/2023. Vested RSUs will be paid in shares of the Company's common stock on a one-to-one basis. These shares include 157 Dividend Equivalents (DEs) granted pursuant to the Amgen Inc. 2009 Equity Incentive Plan and subject to a qualifying dividend reinvestment plan. DEs are credited on the reporting person's unvested RSUs and are paid out in shares of the Company's common stock on a one-to-one basis according to the vesting schedule, along with a cash payment for any remaining fractional share amount. 1,524 of these non-qualified stock options have vested and are exercisable. 2,069 of these non-qualified stock options have vested and are exercisable. 1,201 of these non-qualified stock options have vested and are exercisable and 620 of these options will vest and become exercisable on 4/27/2022. 1,218 of these non-qualified stock options have vested and are exercisable and the remaining options will vest and become exercisable in installments of 1,218 on 5/3/2022 and 1,256 on 5/3/2023. These non-qualified stock options will vest and become exercisable in two installments of 1,110 on 5/5/2022 and 5/5/2023 and one installment of 1,145 on 5/5/2024. These non-qualified stock options will vest and become exercisable in three installments of 1,123 on 4/30/2023, 1,124 on 4/30/2024 and 1,158 on 4/30/2025. /s/ Derek Miller 2022-03-17