Collaborations - BeiGene (Details) - USD ($) $ in Millions		12 Months Ended
	Jan. 02, 2020	Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2022
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Total revenues		$ 33,424	$ 28,190	$ 26,323
BeiGene
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Research and development arrangement, contract to provide cash and development services, maximum amount	$ 1,250
BeiGene
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Equity method investment, aggregate cost	$ 2,800
Research and Development Expense | BeiGene
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Cost recoveries		122	109	199
BeiGene | BeiGene
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]
Total revenues		$ 259	$ 125	$ 64