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Collaborations - AstraZeneca PLC (Details) - USD ($)
$ in Millions
12 Months Ended
Dec. 31, 2024
Dec. 31, 2023
Dec. 31, 2022
AstraZeneca PLC | Cost of Sales      
Collaborative Arrangement and Arrangement Other than Collaborative [Line Items]      
Profit and loss share of expenses $ 412 $ 310 $ 119