Acquisitions and divestitures - Schedule of Total Consideration for ChemoCentryx Inc (Details) - USD ($) $ in Millions	Dec. 31, 2024	Dec. 31, 2023	Dec. 31, 2022	Oct. 20, 2022
Business Acquisition [Line Items]
Goodwill	$ 18,637	$ 18,629	$ 15,529
ChemoCentryx, Inc.
Business Acquisition [Line Items]
Cash and cash equivalents				$ 86
Marketable securities				235
Inventories				41
Goodwill				649
Other liabilities, net				(83)
Deferred tax liability, net				(502)
Total assets acquired, net of liabilities assumed				3,925
ChemoCentryx, Inc. | Developed-product-technology rights
Business Acquisition [Line Items]
Finite-lived intangible assets—developed-product-technology rights				$ 3,499