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Investments - Neumora Therapeutics, Inc. (Details) - USD ($)
$ in Millions
12 Months Ended
Sep. 30, 2021
Dec. 31, 2022
Dec. 31, 2021
Dec. 31, 2020
Schedule of Equity Method Investments [Line Items]        
Payments to Acquire Equity Method Investments   $ 18 $ 157 $ 3,219
Neumora Therapeutics, Inc.        
Schedule of Equity Method Investments [Line Items]        
Ownership percentage 25.90% 24.90% 25.90%  
Payments to Acquire Equity Method Investments   $ 10    
Neumora Therapeutics, Inc.        
Schedule of Equity Method Investments [Line Items]        
Equity Method Investment, Aggregate Cost $ 257      
Payments to Acquire Equity Method Investments 100      
Noncash or Part Noncash Acquisition, Investments Acquired $ 157      
Equity Method Investments, Fair Value Disclosure   335 $ 220  
Equity method investment, change in carrying value   $ 105 $ (37)