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Acquisitions and divestitures - Summary of Total Consideration for ChemoCentryx Inc (Details) - USD ($)
$ in Millions
Dec. 31, 2022
Oct. 20, 2022
Dec. 31, 2021
Dec. 31, 2020
Business Acquisition [Line Items]        
Goodwill $ 15,529   $ 14,890 $ 14,689
ChemoCentryx, Inc.        
Business Acquisition [Line Items]        
Cash and cash equivalents   $ 86    
Marketable securities   235    
Inventories   41    
Goodwill   667    
Other liabilities, net   (85)    
Deferred tax liability, net   (516)    
Total assets acquired, net   3,925    
ChemoCentryx, Inc. | Developed Technology Rights        
Business Acquisition [Line Items]        
Finite-lived intangible assets   $ 3,497