Property, plant and equipment (Tables)

12 Months Ended

Dec. 31, 2022

Property, Plant and Equipment [Abstract]

Components of property, plant and equipment

Property, plant and equipment consisted of the following (dollar amounts in millions):

		December 31,
	Useful life (in years)	2022		2021
Land	—	$	292	$	279
Buildings and improvements	10-40	4,201		4,028
Manufacturing equipment	8-12	3,105		3,080
Laboratory equipment	8-12	1,277		1,193
Fixed equipment	12	2,478		2,402
Capitalized software	3-5	1,215		1,151
Other	5-10	929		862
Construction in progress	—	1,213		987
Property, plant and equipment, gross		14,710		13,982
Less accumulated depreciation and amortization		(9,283)		(8,798)
Property, plant and equipment, net		$	5,427	$	5,184

Property, plant and equipment by geographic information

Certain geographic information with respect to property, plant and equipment, net (long-lived assets), was as follows (in millions):

	December 31,
	2022		2021
U.S.	$	3,154	$	2,801
Puerto Rico	1,247		1,311
ROW	1,026		1,072
Total property, plant and equipment, net	$	5,427	$	5,184