Consolidated Statements of Income - USD ($) shares in Millions, $ in Millions	12 Months Ended
	Dec. 31, 2022	Dec. 31, 2021	Dec. 31, 2020
Revenues:
Total revenues	$ 26,323	$ 25,979	$ 25,424
Operating expenses:
Cost of sales	6,406	6,454	6,159
Research and development	4,434	4,819	4,207
Acquired in-process research and development	0	1,505	0
Selling, general and administrative	5,414	5,368	5,730
Other	503	194	189
Total operating expenses	16,757	18,340	16,285
Operating income	9,566	7,639	9,139
Interest expense, net	(1,406)	(1,197)	(1,262)
Other (expense) income, net	(814)	259	256
Income before income taxes	7,346	6,701	8,133
Provision for income taxes	794	808	869
Net income	$ 6,552	$ 5,893	$ 7,264
Earnings per share:
Basic (in usd per share)	$ 12.18	$ 10.34	$ 12.40
Diluted (in usd per share)	$ 12.11	$ 10.28	$ 12.31
Shares used in the calculation of earnings per share:
Basic (in shares)	538	570	586
Diluted (in shares)	541	573	590
Product sales
Revenues:
Total revenues	$ 24,801	$ 24,297	$ 24,240
Other revenues
Revenues:
Total revenues	$ 1,522	$ 1,682	$ 1,184