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Acquisitions - Narrative (Details) - USD ($)
$ in Millions
3 Months Ended
Mar. 31, 2022
Dec. 31, 2021
Business Acquisition [Line Items]    
Net increase in goodwill $ 22  
Goodwill 14,897 $ 14,890
Teneobio    
Business Acquisition [Line Items]    
Net increase in goodwill 22  
Cash paid 993  
Maximum additional consideration due contingent on certain milestones 1,600  
Contingent consideration obligation for acquisition 299  
Deferred tax liability 244  
Goodwill 273  
Teneobio | R & D Technology rights    
Business Acquisition [Line Items]    
Value of intangible assets acquired $ 115  
Weighted average period of amortization 10 years  
Teneobio | Licensing rights    
Business Acquisition [Line Items]    
Value of intangible assets acquired $ 41  
Teneobio | In-process Research and Development    
Business Acquisition [Line Items]    
Acquired in-process research and development 991  
Teneobio | In-process Research and Development | AMG 340    
Business Acquisition [Line Items]    
Acquired in-process research and development $ 784